The overall goal of this procedure is to provide a novel head-fixation technique using dental acrylic which is widely available in laboratories performing implantation surgery in rodents. This method can answer key questions in the brain and behav
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Traditional head fixation techniques have used metallic frames attached on the skull as an interface for head fixation apparatus. This protocol demonstrates a frameless, acrylic resin molding based head fixation technique for behavioral tasks in rodents.