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JoVE Journal

Medicine

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Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique

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08:25 min

June 2nd, 2016

June 2nd, 2016

7,758 Views

0:05

Title

0:40

Identification of the Forelimb Area in the Internal Capsule Using AAV-GFP

3:09

Construction of the Optical Neural Interface

4:41

Photothrombotic Infarct of the Internal Capsule

6:44

Results: Microscopic Appearance of Capsular Infarct after Photothrombosis

7:38

Conclusion

Transcribir

The overall goal of this technique is to create a circumscribed capsular infarct model with a persistent motor impairment using photothrombotic technique. Before creating the capsular infarct, it is necessary to identify the forelimb area in the i

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This manuscript describes a modeling technique of capsular infarct. Here we utilized a modified photothrombotic technique with low intensity of light after pre-surgery target mapping. Using this technique, we created a circumscribed capsular infarct model with persistent motor impairment.

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