Results: Measurement of Conducticity Cganges Upon Antibiotic Hydrolysis by the Immobilization Chimeric β-Lactamase
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The overall goal of this Conductimetric Biosensor Assay is to detect biomolecular interactions, using the hybrid beta-lactamase technology. We describe a method to detect antibody antigen interactions, using a chimeric beta-lactamase protein. The
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In this work, we report a new method to study protein-protein interactions using a conductimetric biosensor based on the hybrid β-lactamase technology. This method relies on release of protons upon hydrolysis of β-lactams.