Results: Representative Active and Passive Tension Analyses
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Conclusion
Transcripción
Assessing the contractile properties of myofibrils isolated from striated muscle can be used to determine whether sarcomere dysfunction is a primary cause of muscle weakness due to mutations in sarcomeric proteins. This technique can be used to ac
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Presented here is a protocol to assess the contractile properties of striated muscle myofibrils with nano-Newton resolution. The protocol employs a setup with an interferometry-based, optical force probe. This setup generates data with a high signal-to-noise ratio and enables the assessment of the contractile kinetics of myofibrils.