Results: Assessment of Intervertebral Disc Degeneration Caused by Degenerative Loading, Limited Nutrition, and TNF-α Injection
4:59
Conclusion
Transcripción
The protocol aims to simulate in vivo conditions of intervertebral disc degeneration to investigate its pathophysiology without the need for animal models. Compared with in vitro cell culture, the bioreactor organ culture technique maintains the c
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This protocol presents a novel experimental model of proinflammatory, degenerative bovine organ culture to simulate early-stage intervertebral disc degeneration.