Department of Molecular Physiology and Biophysics
Wenbiao Chen has not added Biography.
If you are Wenbiao Chen and would like to personalize this page please email our Author Liaison for assistance.
A gain-of-function screen in zebrafish identifies a guanylate cyclase with a role in neuronal degeneration.
Molecular genetics and genomics : MGG May, 2009 | Pubmed ID: 19221799
FlEx-based transgenic reporter lines for visualization of Cre and Flp activity in live zebrafish.
Genesis (New York, N.Y. : 2000) Jul, 2009 | Pubmed ID: 19415631
Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish.
Molecular cancer , 2009 | Pubmed ID: 19555497
PhiC31 integrase induces efficient site-specific excision in zebrafish.
Transgenic research Feb, 2011 | Pubmed ID: 20556509
Pineal-specific agouti protein regulates teleost background adaptation.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2010 | Pubmed ID: 20980662
Generating conditional mutations in zebrafish using gene-trap mutagenesis.
Methods in cell biology , 2011 | Pubmed ID: 21924154
Nutrient excess stimulates β-cell neogenesis in zebrafish.
Diabetes Oct, 2012 | Pubmed ID: 22721970
Conditional control of gene function by an invertible gene trap in zebrafish.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2012 | Pubmed ID: 22908272
Targeted overexpression of CKI-insensitive cyclin-dependent kinase 4 increases functional β-cell number through enhanced self-replication in zebrafish.
Zebrafish Jun, 2013 | Pubmed ID: 23544990
Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2013 | Pubmed ID: 23918387
Conditional gene-trap mutagenesis in zebrafish.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24233792
Overnutrition induces β-cell differentiation through prolonged activation of β-cells in zebrafish larvae.
American journal of physiology. Endocrinology and metabolism Apr, 2014 | Pubmed ID: 24473439
Spatial regionalization and heterochrony in the formation of adult pallial neural stem cells.
Developmental cell Jul, 2014 | Pubmed ID: 25017692
Oncogenic KRAS promotes malignant brain tumors in zebrafish.
Molecular cancer Feb, 2015 | Pubmed ID: 25644510
Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner.
American journal of physiology. Endocrinology and metabolism Apr, 2015 | Pubmed ID: 25670827
Circadian modulation of dopamine levels and dopaminergic neuron development contributes to attention deficiency and hyperactive behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2015 | Pubmed ID: 25673850
Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs.
Genetics Jun, 2015 | Pubmed ID: 25855067
High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
Genome research Jul, 2015 | Pubmed ID: 26048245
Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation.
Neuro-oncology Jan, 2016 | Pubmed ID: 26136493
A conserved role of αA-crystallin in the development of the zebrafish embryonic lens.
Experimental eye research Sep, 2015 | Pubmed ID: 26149094
Generation of Targeted Mutations in Zebrafish Using the CRISPR/Cas System.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 26285757
FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation.
Diabetes Jan, 2016 | Pubmed ID: 26420862
Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish.
The Journal of endocrinology Nov, 2015 | Pubmed ID: 26446275
Active medulloblastoma enhancers reveal subgroup-specific cellular origins.
Nature Feb, 2016 | Pubmed ID: 26814967
Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2016 | Pubmed ID: 26903647
Zebrafish Genome Engineering Using the CRISPR-Cas9 System.
Trends in genetics : TIG Dec, 2016 | Pubmed ID: 27836208
Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase.
Autophagy Feb, 2017 | Pubmed ID: 27875093
Modeling Pancreatic Endocrine Cell Adaptation and Diabetes in the Zebrafish.
Frontiers in endocrinology , 2017 | Pubmed ID: 28184214
Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
Cell metabolism Jun, 2017 | Pubmed ID: 28591638
Ahmed Elaswad*,1,2,
Karim Khalil*,1,3,
David Cline1,
Patrick Page-McCaw4,
Wenbiao Chen4,
Maximilian Michel5,
Roger Cone5,
Rex Dunham1
1School of Fisheries, Aquaculture and Aquatic Sciences, Auburn University,
2Department of Animal Wealth Development, Faculty of Veterinary Medicine, Suez Canal University,
3Anatomy and Embryology Department, Faculty of Veterinary Medicine, Cairo University,
4Department of Molecular Physiology and Biophysics, Vanderbilt University,
5Life Science Institute, University of Michigan