McAllister Heart Institute
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A new gun in town: the U box is a ubiquitin ligase domain.
Science's STKE : signal transduction knowledge environment Jan, 2002 | Pubmed ID: 11805346
Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts.
Circulation Feb, 2002 | Pubmed ID: 11864929
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.
The EMBO journal May, 2002 | Pubmed ID: 12006493
Things have changed: cell cycle dysregulation and smooth muscle cell dysfunction in atherogenesis.
Ageing research reviews Apr, 2002 | Pubmed ID: 12039437
A noncoding RNA regulates human protease-activated receptor-1 gene during embryogenesis.
Biochimica et biophysica acta Jul, 2002 | Pubmed ID: 12084570
Tiny dancers: the integrin-growth factor nexus in angiogenic signaling.
The Journal of cell biology Jul, 2002 | Pubmed ID: 12105178
Protein quality control: U-box-containing E3 ubiquitin ligases join the fold.
Trends in biochemical sciences Jul, 2002 | Pubmed ID: 12114026
Mitochondrial integrity and function in atherogenesis.
Circulation Jul, 2002 | Pubmed ID: 12147534
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12239347
HIV therapies and atherosclerosis: answers or questions?
Arteriosclerosis, thrombosis, and vascular biology Nov, 2002 | Pubmed ID: 12426201
Welcome to the machine: a cardiologist's introduction to protein folding and degradation.
Circulation Nov, 2002 | Pubmed ID: 12438302
Evidence for association of coronary sinus levels of hepatocyte growth factor and collateralization in human coronary disease.
American journal of physiology. Heart and circulatory physiology May, 2003 | Pubmed ID: 12521946
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.
Molecular biology of the cell Jan, 2003 | Pubmed ID: 12529448
C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation.
Archives of biochemistry and biophysics Feb, 2003 | Pubmed ID: 12559985
Break the cycle: the role of cell-cycle modulation in the prevention of vasculoproliferative diseases.
Cell cycle (Georgetown, Tex.) May-Jun, 2003 | Pubmed ID: 12734427
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling.
The EMBO journal Jun, 2003 | Pubmed ID: 12773386
AtCHIP, a U-box-containing E3 ubiquitin ligase, plays a critical role in temperature stress tolerance in Arabidopsis.
Plant physiology Jun, 2003 | Pubmed ID: 12805616
Thrombin and vascular development: a sticky subject.
Arteriosclerosis, thrombosis, and vascular biology Jun, 2003 | Pubmed ID: 12807713
The Ponzo effect: endothelial progenitor cells appear on the horizon.
Circulation Jun, 2003 | Pubmed ID: 12821584
Overexpression of the cochaperone CHIP enhances Hsp70-dependent folding activity in mammalian cells.
Molecular and cellular biology Jul, 2003 | Pubmed ID: 12832480
BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.
Molecular and cellular biology Aug, 2003 | Pubmed ID: 12897139
HoxB5 is an upstream transcriptional switch for differentiation of the vascular endothelium from precursor cells.
Molecular and cellular biology Aug, 2003 | Pubmed ID: 12897140
Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14507928
CHIP activates HSF1 and confers protection against apoptosis and cellular stress.
The EMBO journal Oct, 2003 | Pubmed ID: 14532117
PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase.
Journal of cellular physiology Feb, 2004 | Pubmed ID: 14603533
Catecholamine-induced vascular wall growth is dependent on generation of reactive oxygen species.
Circulation research Jan, 2004 | Pubmed ID: 14656924
Age-related changes in matrix metalloproteinase-9 regulation in cultured mouse aortic smooth muscle cells.
Experimental gerontology Jan, 2004 | Pubmed ID: 14724072
p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14966113
Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein.
Journal of molecular biology Mar, 2004 | Pubmed ID: 15001357
Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation.
Brain research. Molecular brain research Apr, 2004 | Pubmed ID: 15046863
Younger than yesterday: is vascular senescence a two-way street?
Circulation research Apr, 2004 | Pubmed ID: 15059938
An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP).
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15107424
CHIP: a link between the chaperone and proteasome systems.
Cell stress & chaperones , 2003 | Pubmed ID: 15115282
LE-PAS, a novel Arnt-dependent HLH-PAS protein, is expressed in limbic tissues and transactivates the CNS midline enhancer element.
Brain research. Molecular brain research Sep, 2004 | Pubmed ID: 15363889
Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase.
The Journal of biological chemistry Dec, 2004 | Pubmed ID: 15466472
Universal mouse reference RNA derived from neonatal mice.
BioTechniques Sep, 2004 | Pubmed ID: 15470901
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex.
The Journal of clinical investigation Oct, 2004 | Pubmed ID: 15489953
Blood pressure control goes nuclear.
Circulation research Oct, 2004 | Pubmed ID: 15514165
A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters.
Molecular and cellular biology Dec, 2004 | Pubmed ID: 15572660
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy.
The Journal of cell biology Dec, 2004 | Pubmed ID: 15596539
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2004 | Pubmed ID: 15601779
A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase.
The Journal of cell biology Dec, 2004 | Pubmed ID: 15611333
CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice.
American journal of physiology. Heart and circulatory physiology Jun, 2005 | Pubmed ID: 15665051
Adenosine produces nitric oxide and prevents mitochondrial oxidant damage in rat cardiomyocytes.
Cardiovascular research Mar, 2005 | Pubmed ID: 15721860
Differential activation of mitogenic signaling pathways in aortic smooth muscle cells deficient in superoxide dismutase isoforms.
Arteriosclerosis, thrombosis, and vascular biology May, 2005 | Pubmed ID: 15746439
The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways.
The Journal of biological chemistry Jun, 2005 | Pubmed ID: 15845543
Cystic fibrosis transmembrane conductance regulator as a model substrate to study endoplasmic reticulum protein quality control in mammalian cells.
Methods in molecular biology (Clifton, N.J.) , 2005 | Pubmed ID: 15917641
C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis.
Cell stress & chaperones , 2005 | Pubmed ID: 16038411
Mechanisms of endothelial differentiation in embryonic vasculogenesis.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2005 | Pubmed ID: 16123328
Even flow: shear cues vascular development.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2005 | Pubmed ID: 16127024
Regulation of the cytoplasmic quality control protein degradation pathway by BAG2.
The Journal of biological chemistry Nov, 2005 | Pubmed ID: 16169850
Direct identification of ubiquitination sites on ubiquitin-conjugated CHIP using MALDI mass spectrometry.
Journal of proteome research Sep-Oct, 2005 | Pubmed ID: 16212406
Bone morphogenetic proteins and vascular differentiation: BMPing up vasculogenesis.
Thrombosis and haemostasis Oct, 2005 | Pubmed ID: 16270622
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP.
The Journal of cell biology Dec, 2005 | Pubmed ID: 16344307
ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway.
American journal of physiology. Heart and circulatory physiology May, 2006 | Pubmed ID: 16361361
A combined strategy to reduce restenosis for vascular tissue engineering applications.
Biotechnology progress Jan-Feb, 2006 | Pubmed ID: 16454490
The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2006 | Pubmed ID: 16469848
Abciximab-associated thrombocytopenia after previous tirofiban-related thrombocytopenia.
Pharmacotherapy Mar, 2006 | Pubmed ID: 16503724
A salty salute: progenitor cell therapies and no-option heart disease.
American heart journal Mar, 2006 | Pubmed ID: 16504614
Search and destroy: the role of protein quality control in maintaining cardiac function.
Journal of molecular and cellular cardiology Apr, 2006 | Pubmed ID: 16516914
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70.
Nature Mar, 2006 | Pubmed ID: 16554822
Gene expression profile signatures indicate a role for Wnt signaling in endothelial commitment from embryonic stem cells.
Circulation research May, 2006 | Pubmed ID: 16601226
Comparative effects of paclitaxel and rapamycin on smooth muscle migration and survival: role of AKT-dependent signaling.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2006 | Pubmed ID: 16645158
Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2006 | Pubmed ID: 16807328
CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.
The Journal of biological chemistry Sep, 2006 | Pubmed ID: 16831871
Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP.
The Biochemical journal Dec, 2006 | Pubmed ID: 16895519
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.
Cell Aug, 2006 | Pubmed ID: 16901789
Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.
The Journal of biological chemistry Oct, 2006 | Pubmed ID: 16931512
Into the heart: the emerging role of the ubiquitin-proteasome system.
Journal of molecular and cellular cardiology Oct, 2006 | Pubmed ID: 16949602
Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies.
The Journal of biological chemistry Jan, 2007 | Pubmed ID: 17098737
Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses.
Blood Apr, 2007 | Pubmed ID: 17119124
Brain CHIP: removing the culprits in neurodegenerative disease.
Trends in molecular medicine Jan, 2007 | Pubmed ID: 17127096
2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells.
Cancer research Jan, 2007 | Pubmed ID: 17234781
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo.
Circulation research Mar, 2007 | Pubmed ID: 17272810
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.
The Journal of clinical investigation Mar, 2007 | Pubmed ID: 17304350
CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.
Human molecular genetics Apr, 2007 | Pubmed ID: 17317785
The bitter end: the ubiquitin-proteasome system and cardiac dysfunction.
Circulation Mar, 2007 | Pubmed ID: 17372187
Diminished GATA4 protein levels contribute to hyperglycemia-induced cardiomyocyte injury.
The Journal of biological chemistry Jul, 2007 | Pubmed ID: 17525155
Chaperone functions of the E3 ubiquitin ligase CHIP.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17545168
Characterization of a model to independently study regression of ventricular hypertrophy.
The Journal of surgical research Oct, 2007 | Pubmed ID: 17574596
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish.
Journal of molecular and cellular cardiology Sep, 2007 | Pubmed ID: 17618647
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism.
Molecular and cellular biology Sep, 2007 | Pubmed ID: 17636018
Selection and initial characterization of novel peptide ligands that bind specifically to human blood outgrowth endothelial cells.
Biotechnology and bioengineering Sep, 2007 | Pubmed ID: 17657770
PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation.
Journal of molecular and cellular cardiology Jan, 2008 | Pubmed ID: 17662997
ERK signaling is a central regulator for BMP-4 dependent capillary sprouting.
Cardiovascular research Dec, 2007 | Pubmed ID: 17850776
Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.
American journal of physiology. Heart and circulatory physiology Nov, 2007 | Pubmed ID: 17873020
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.
The Journal of clinical investigation Nov, 2007 | Pubmed ID: 17965779
Twin layers of lightning: a new role for the chaperone Hsp90 in angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2008 | Pubmed ID: 17975116
The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle.
Cell metabolism Nov, 2007 | Pubmed ID: 17983583
CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2008 | Pubmed ID: 18079406
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors.
The Journal of cell biology Dec, 2007 | Pubmed ID: 18158328
Partners in crime: how two Sox proteins cooperate to specify arterial fate.
Circulation research Jan, 2008 | Pubmed ID: 18174468
You spin me round: MaFBx/Atrogin-1 feeds forward on FOXO transcription factors (like a record).
Cell cycle (Georgetown, Tex.) Feb, 2008 | Pubmed ID: 18235241
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18256189
Akt and CHIP coregulate tau degradation through coordinated interactions.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2008 | Pubmed ID: 18292230
Molecular characterization of human breast tumor vascular cells.
The American journal of pathology May, 2008 | Pubmed ID: 18403594
CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control.
Molecular and cellular biology Jun, 2008 | Pubmed ID: 18411298
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
The Journal of cell biology Jun, 2008 | Pubmed ID: 18504303
Selective endothelial cell attachment to peptide-modified terpolymers.
Biomaterials Sep, 2008 | Pubmed ID: 18556061
Therapeutic options for premature coronary artery disease.
Current treatment options in cardiovascular medicine Aug, 2008 | Pubmed ID: 18647585
Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males.
BMC medical genomics , 2008 | Pubmed ID: 18710571
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis.
Circulation research Oct, 2008 | Pubmed ID: 18787191
Zinc fingers in the pizza pie aorta.
Circulation research Sep, 2008 | Pubmed ID: 18818412
CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.
Molecular cell Sep, 2008 | Pubmed ID: 18922468
Brothers and sisters: molecular insights into arterial-venous heterogeneity.
Circulation research Oct, 2008 | Pubmed ID: 18948631
Build it up-Tear it down: protein quality control in the cardiac sarcomere.
Cardiovascular research Feb, 2009 | Pubmed ID: 18974044
The opening act: vasculogenesis and the origins of circulation.
Arteriosclerosis, thrombosis, and vascular biology May, 2009 | Pubmed ID: 19008532
Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2.
Nature structural & molecular biology Dec, 2008 | Pubmed ID: 19029896
CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases.
Archives of biochemistry and biophysics Mar, 2009 | Pubmed ID: 19103148
Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile.
The Journal of thoracic and cardiovascular surgery Jan, 2009 | Pubmed ID: 19154930
Muscle ring finger 1 mediates cardiac atrophy in vivo.
American journal of physiology. Heart and circulatory physiology Apr, 2009 | Pubmed ID: 19168726
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19196961
Torturing a blood vessel.
Nature medicine Feb, 2009 | Pubmed ID: 19197284
A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling.
The Journal of cell biology Feb, 2009 | Pubmed ID: 19221194
CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation.
Molecular and cellular biology May, 2009 | Pubmed ID: 19237536
Breast cancer quality control.
Nature cell biology Mar, 2009 | Pubmed ID: 19255569
SDF-1alpha stimulates JNK3 activity via eNOS-dependent nitrosylation of MKP7 to enhance endothelial migration.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2009 | Pubmed ID: 19307591
New insights into bone morphogenetic protein signaling: focus on angiogenesis.
Current opinion in hematology May, 2009 | Pubmed ID: 19346940
HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2.
Cardiovascular research Aug, 2009 | Pubmed ID: 19403561
Black and white: rapamycin as a regulator of cardiac mTOR signaling.
Cell cycle (Georgetown, Tex.) Jun, 2009 | Pubmed ID: 19454842
Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway.
Cancer research Jun, 2009 | Pubmed ID: 19458075
Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program.
The Journal of biological chemistry Jul, 2009 | Pubmed ID: 19465479
C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.
The Journal of biological chemistry Jul, 2009 | Pubmed ID: 19483080
Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo.
Circulation research Jul, 2009 | Pubmed ID: 19498199
Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease.
Future cardiology Jan, 2008 | Pubmed ID: 19543439
Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer.
The Journal of biological chemistry Sep, 2009 | Pubmed ID: 19648119
Krüppel-like factor 15 regulates BMPER in endothelial cells.
Cardiovascular research Feb, 2010 | Pubmed ID: 19767294
Seek and destroy: the ubiquitin----proteasome system in cardiac disease.
Current hypertension reports Dec, 2009 | Pubmed ID: 19895750
Minireview: Won't get fooled again: the nonmetabolic roles of peroxisome proliferator-activated receptors (PPARs) in the heart.
Molecular endocrinology (Baltimore, Md.) Jun, 2010 | Pubmed ID: 20016041
Stable patterns of gene expression regulating carbohydrate metabolism determined by geographic ancestry.
PloS one , 2009 | Pubmed ID: 20016837
BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2010 | Pubmed ID: 20042706
Hard luck stories: the reality of endothelial progenitor cells continues to fall short of the promise.
Circulation Feb, 2010 | Pubmed ID: 20142453
The FoxO family in cardiac function and dysfunction.
Annual review of physiology , 2010 | Pubmed ID: 20148668
Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.
Circulation research Feb, 2010 | Pubmed ID: 20167943
Gyrate: CCM3 dances with a different angiogenic partner.
Science signaling , 2010 | Pubmed ID: 20484115
Development of the endothelium: an emphasis on heterogeneity.
Seminars in thrombosis and hemostasis Apr, 2010 | Pubmed ID: 20490975
A good idea: a physician's perspective on genetic counseling for hypertrophic cardiomyopathy.
Journal of cardiovascular translational research Dec, 2009 | Pubmed ID: 20560009
mTORC1 links protein quality and quantity control by sensing chaperone availability.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20605781
Cardiac muscle ring finger-1--friend or foe?
Trends in cardiovascular medicine Jan, 2010 | Pubmed ID: 20685572
Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2010 | Pubmed ID: 20724525
Closer to fine: fewer steps to endothelial stemness.
Arteriosclerosis, thrombosis, and vascular biology Oct, 2010 | Pubmed ID: 20844268
C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.
American journal of respiratory cell and molecular biology Jul, 2011 | Pubmed ID: 20870896
CHIP-dependent p53 regulation occurs specifically during cellular senescence.
Free radical biology & medicine Jan, 2011 | Pubmed ID: 20974249
Hold me tight: Role of the heat shock protein family of chaperones in cardiac disease.
Circulation Oct, 2010 | Pubmed ID: 20975010
Recombinant human interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2011 | Pubmed ID: 21071685
Evaluating age-associated phenotypes in a mouse model of protein dyshomeostasis.
Methods (San Diego, Calif.) Mar, 2011 | Pubmed ID: 21167942
Regulation of AMPK by the ubiquitin proteasome system.
The American journal of pathology Jan, 2011 | Pubmed ID: 21224036
Tearin' up my heart: proteolysis in the cardiac sarcomere.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21257759
Efficient in vivo selection of a novel tumor-associated peptide from a phage display library.
Molecules (Basel, Switzerland) , 2011 | Pubmed ID: 21258297
The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun.
The American journal of pathology Mar, 2011 | Pubmed ID: 21356357
NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo.
The American journal of pathology Mar, 2011 | Pubmed ID: 21356358
Regulation of ankyrin repeat and suppressor of cytokine signalling box protein 4 expression in the immortalized murine endothelial cell lines MS1 and SVR: a role for tumour necrosis factor alpha and oxygen.
Cell biochemistry and function Jun, 2011 | Pubmed ID: 21506136
The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus.
PloS one , 2011 | Pubmed ID: 21673995
Rise above: muscle ring-finger-1 (MURF1) regulation of cardiomyocyte size and energy metabolism.
Transactions of the American Clinical and Climatological Association , 2011 | Pubmed ID: 21686210
Bone morphogenetic protein endothelial cell precursor-derived regulator regulates retinal angiogenesis in vivo in a mouse model of oxygen-induced retinopathy.
Arteriosclerosis, thrombosis, and vascular biology Oct, 2011 | Pubmed ID: 21737784
Tear me down: role of calpain in the development of cardiac ventricular hypertrophy.
Circulation research Aug, 2011 | Pubmed ID: 21817165
Regulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy.
Muscle & nerve Oct, 2011 | Pubmed ID: 21826685
Reconstitution of CHIP E3 ubiquitin ligase activity.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21898230
BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.
Blood Nov, 2011 | Pubmed ID: 21900199
Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation.
BMC neuroscience , 2011 | Pubmed ID: 21955513
Back to your heart: ubiquitin proteasome system-regulated signal transduction.
Journal of molecular and cellular cardiology Mar, 2012 | Pubmed ID: 22085703
BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice.
The Journal of biological chemistry Feb, 2012 | Pubmed ID: 22144676
Life is a pattern: vascular assembly within the embryo.
Frontiers in bioscience (Elite edition) , 2012 | Pubmed ID: 22202036
The expanding world of post-translational modifications.
Journal of molecular and cellular cardiology Mar, 2012 | Pubmed ID: 22265974
p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.
Circulation research Feb, 2012 | Pubmed ID: 22267842
A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting.
American journal of respiratory and critical care medicine Apr, 2012 | Pubmed ID: 22312013
Recovery from decompensated heart failure is associated with a distinct, phase-dependent gene expression profile.
The Journal of surgical research Nov, 2012 | Pubmed ID: 22480839
The ubiquitin-proteasome system and cardiovascular disease.
Progress in molecular biology and translational science , 2012 | Pubmed ID: 22727426
Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2012 | Pubmed ID: 22772758
LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis.
Circulation research Aug, 2012 | Pubmed ID: 22777006
PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.
The Journal of clinical investigation Aug, 2012 | Pubmed ID: 22797300
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy Apr, 2012 | Pubmed ID: 22966490
Lysine 48-linked polyubiquitination of organic anion transporter-1 is essential for its protein kinase C-regulated endocytosis.
Molecular pharmacology Jan, 2013 | Pubmed ID: 23087261
ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.
Molecular and cellular biology Jan, 2013 | Pubmed ID: 23129809
BMPER regulates cardiomyocyte size and vessel density in vivo.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology May-Jun, 2013 | Pubmed ID: 23200275
Proteotoxicity and cardiac dysfunction--Alzheimer's disease of the heart?
The New England journal of medicine Jan, 2013 | Pubmed ID: 23363499
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo.
Cell biochemistry and function Mar, 2013 | Pubmed ID: 23512667
Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise.
Cell biochemistry and function Apr, 2013 | Pubmed ID: 23553918
A novel monoclonal antibody to secreted frizzled-related protein 2 inhibits tumor growth.
Molecular cancer therapeutics May, 2013 | Pubmed ID: 23604067
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response.
The EMBO journal May, 2013 | Pubmed ID: 23612611
Proteotoxicity and cardiac dysfunction.
The New England journal of medicine May, 2013 | Pubmed ID: 23635068
Antagonism and synergy between extracellular BMP modulators Tsg and BMPER to balance blood vessel formation.
Journal of cell science May, 2013 | Pubmed ID: 23641068
Development of a new positron emission tomography tracer for targeting tumor angiogenesis: synthesis, small animal imaging, and radiation dosimetry.
Molecules (Basel, Switzerland) , 2013 | Pubmed ID: 23676470
Diggin' on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin Ligase Substrates.
Cell biochemistry and biophysics May, 2013 | Pubmed ID: 23695782
Inhibition of BMP activity protects epithelial barrier function in lung injury.
The Journal of pathology May, 2013 | Pubmed ID: 23716395