JoVE Logo
Centre de ressources universitaires

S'identifier

Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination

DOI :

10.3791/52934-v

July 29th, 2015

July 29th, 2015

11,819 Views

1Department of Ophthalmology, Australian School of Advanced Medicine, Macquarie University, 2Save Sight Institute, The University of Sydney

Focal demyelination is induced in the optic nerve using lysolecithin microinjection. Visual evoked potentials are recorded via skull electrodes implanted over the visual cortex to examine the signal conduction along the visual pathway in vivo. This protocol details the surgical procedures underlying electrode implantation and optic nerve microinjection.

Tags

Visual Evoked Potential

-- Vues

Vidéos Connexes

article

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

article

Methods for Experimental Manipulations after Optic Nerve Transection in the Mammalian CNS

article

An Optic Nerve Crush Injury Murine Model to Study Retinal Ganglion Cell Survival

article

Determination of Mitochondrial Membrane Potential and Reactive Oxygen Species in Live Rat Cortical Neurons

article

Minimally-invasive Technique for Injection into Rat Optic Nerve

article

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

article

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments

article

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

article

Visual Evoked Potential Recordings in Mice Using a Dry Non-invasive Multi-channel Scalp EEG Sensor

article

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines

JoVE Logo

Confidentialité

Conditions d'utilisation

Politiques

Recherche

Enseignement

À PROPOS DE JoVE

Copyright © 2024 MyJoVE Corporation. Tous droits réservés.