Les résultats décrits sont obtenus à partir du projet soutenu par le Centre national des sciences en Pologne dans le cadre de la subvention n° 2014/13/B/HS6/03155.

<ol>
	<li>Baddeley, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+memory:+Looking+back+and+looking+forward.">Working memory: Looking back and looking forward.</a> Nature Reviews Neuroscience. , (2003).</li><li>Au, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Improving+fluid+intelligence+with+training+on+working+memory:+a+meta-analysis.">Improving fluid intelligence with training on working memory: a meta-analysis.</a> Psychonomic Bulletin and Review. 22, 366-377 (2015).</li><li>Karbach, J., Verhaeghen, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Making+working+memory+work:+A+meta-analysis+of+executive+control+and+working+memory+training+in+younger+and+older+adults.">Making working memory work: A meta-analysis of executive control and working memory training in younger and older adults.</a> Psychological Science. 25, 11-2027 (2014).</li><li>Melby-Lerv&#229;g, M., Hulme, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Is+working+memory+training+effective?+A+meta-analytic+review.">Is working memory training effective? A meta-analytic review.</a> Developmental Psychology. , (2013).</li><li>Melby-Lerv&#229;g, M., Redick, T. S., Hulme, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+Memory+Training+Does+Not+Improve+Performance+on+Measures+of+Intelligence+or+Other+Measures+of+&amp;#34;Far+Transfer&amp;#34;:+Evidence+From+a+Meta-Analytic+Review.">Working Memory Training Does Not Improve Performance on Measures of Intelligence or Other Measures of &amp;#34;Far Transfer&amp;#34;: Evidence From a Meta-Analytic Review.</a> Perspectives on Psychological Science. , (2016).</li><li>Schwaighofer, M., Fischer, F., B&#252;hner, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Does+Working+Memory+Training+Transfer?+A+Meta-Analysis+Including+Training+Conditions+as+Moderators.">Does Working Memory Training Transfer? A Meta-Analysis Including Training Conditions as Moderators.</a> Educational Psychologist. , (2015).</li><li>Soveri, A., Antfolk, J., Karlsson, L., Salo, B., Laine, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+memory+training+revisited:+A+multi-level+meta-analysis+of+n-back+training+studies.">Working memory training revisited: A multi-level meta-analysis of n-back training studies.</a> Psychonomic Bulletin and Review. , (2017).</li><li>Au, J., Buschkuehl, M., Duncan, G. J., Jaeggi, S. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=There+is+no+convincing+evidence+that+working+memory+training+is+NOT+effective:+A+reply+to+Melby-Lerv&#229;g+and+Hulme+(2015).">There is no convincing evidence that working memory training is NOT effective: A reply to Melby-Lerv&#229;g and Hulme (2015).</a> Psychonomic Bulletin and Review. , (2016).</li><li>Dougherty, M. R., Hamovitz, T., Tidwell, J. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Reevaluating+the+effectiveness+of+n-back+training+on+transfer+through+the+Bayesian+lens:+Support+for+the+null.">Reevaluating the effectiveness of n-back training on transfer through the Bayesian lens: Support for the null.</a> Psychonomic Bulletin and Review. , (2016).</li><li>L&#246;vd&#233;n, M., B&#228;ckman, L., Lindenberger, U., Schaefer, S., Schmiedek, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> A Theoretical Framework for the Study of Adult Cognitive Plasticity. , (2010).</li><li>Shinaver, C. S., Entwistle, P. C., S&#246;derqvist, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cogmed+WM+Training:+Reviewing+the+Reviews.">Cogmed WM Training: Reviewing the Reviews.</a> Applied Neuropsychology: Child. , (2014).</li><li>Shipstead, Z., Redick, T. S., Engle, R. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Does+working+memory+training+generalize?.">Does working memory training generalize?.</a> Psychologica Belgica. , (2010).</li><li>Shipstead, Z., Redick, T. S., Engle, R. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Is+working+memory+training+effective?.">Is working memory training effective?.</a> Psychological Bulletin. 138 (4), 628-654 (2012).</li><li>Weicker, J., Villringer, A., Th&#246;ne-Otto, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Can+impaired+working+memory+functioning+be+improved+by+training?+A+meta-analysis+with+a+special+focus+on+brain+injured+patients.">Can impaired working memory functioning be improved by training? A meta-analysis with a special focus on brain injured patients.</a> Neuropsychology. , (2016).</li><li>Brehmer, Y., Westerberg, H., B&#228;ckman, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working-memory+training+in+younger+and+older+adults:+Training+gains,+transfer,+and+maintenance.">Working-memory training in younger and older adults: Training gains, transfer, and maintenance.</a> Frontiers in Human Neuroscience. , (2012).</li><li>Dahlin, E., Neely, A. S., Larsson, A., B&#228;ckman, L., Nyberg, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Transfer of learning after updating training mediated by the striatum. , (2008).</li><li>Dorbath, L., Hasselhorn, M., Titz, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Aging+and+executive+functioning:+A+training+study+on+focus-switching.">Aging and executive functioning: A training study on focus-switching.</a> Frontiers in Psychology. , (2011).</li><li>Heinzel, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+memory+training+improvements+and+gains+in+non-trained+cognitive+tasks+in+young+and+older+adults.">Working memory training improvements and gains in non-trained cognitive tasks in young and older adults.</a> Aging, Neuropsychology, and Cognition. , (2014).</li><li>Schmiedek, F., L&#246;vd&#233;n, M., Lindenberger, U. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Hundred+days+of+cognitive+training+enhance+broad+cognitive+abilities+in+adulthood:+Findings+from+the+COGITO+study.">Hundred days of cognitive training enhance broad cognitive abilities in adulthood: Findings from the COGITO study.</a> Frontiers in Aging Neuroscience. , (2010).</li><li>Zinke, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+memory+training+and+transfer+in+older+adults:+Effects+of+age,+baseline+performance,+and+training+gains.">Working memory training and transfer in older adults: Effects of age, baseline performance, and training gains.</a> Developmental Psychology. 50 (1), 304-315 (2014).</li><li>B&#252;rki, C. N., Ludwig, C., Chicherio, C., de Ribaupierre, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Individual+differences+in+cognitive+plasticity:+an+investigation+of+training+curves+in+younger+and+older+adults.">Individual differences in cognitive plasticity: an investigation of training curves in younger and older adults.</a> Psychological Research. , (2014).</li><li>Li, S. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+Memory+Plasticity+in+Old+Age:+Practice+Gain,+Transfer,+and+Maintenance+.">Working Memory Plasticity in Old Age: Practice Gain, Transfer, and Maintenance .</a> Psychology and Aging. , (2008).</li><li>Richmond, L. L., Morrison, A. B., Chein, J. M., Olson, I. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+memory+training+and+transfer+in+older+adults.">Working memory training and transfer in older adults.</a> Psychology and Aging. 26 (4), 813-822 (2011).</li><li>von Bastian, C. C., Oberauer, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+and+mechanisms+of+working+memory+training:+a+review.">Effects and mechanisms of working memory training: a review.</a> Psychological Research. 78 (6), 803-820 (2014).</li><li>Zaj&#261;c-Lamparska, L., Trempa&#322;a, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+working+memory+and+attentional+control+training+and+their+transfer+onto+fluid+intelligence+in+early+and+late+adulthood.">Effects of working memory and attentional control training and their transfer onto fluid intelligence in early and late adulthood.</a> Health Psychology Report. 4 (1), 41-53 (2016).</li><li>Verhaeghen, P., Marcoen, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=On+the+mechanisms+of+plasticity+in+young+and+older+adults+after+instruction+in+the+method+of+loci:+Evidence+for+an+amplification+model.">On the mechanisms of plasticity in young and older adults after instruction in the method of loci: Evidence for an amplification model.</a> Psychology and Aging. , (1996).</li><li>Borella, E., Carbone, E., Pastore, M., De Beni, R., Carretti, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Working+memory+training+for+healthy+older+adults:+The+role+of+individual+characteristics+in+explaining+short-+and+long-term+gains.">Working memory training for healthy older adults: The role of individual characteristics in explaining short- and long-term gains.</a> Frontiers in Human Neuroscience. , (2017).</li><li>Bakermans-Kranenburg, M. J., Van Uzendoorn, M. H., Bradley, R. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Those+who+have,+receive:+The+matthew+effect+in+early+childhood+intervention+in+the+home+environment.">Those who have, receive: The matthew effect in early childhood intervention in the home environment.</a> Review of Educational Research. , (2005).</li><li>Foster, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Do+the+effects+of+working+memory+training+depend+on+baseline+ability+level?.">Do the effects of working memory training depend on baseline ability level?.</a> Journal of Experimental Psychology: Learning Memory and Cognition. 43 (11), 1677-1689 (2017).</li><li>Kliegel, M., B&#252;rki, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Memory+training+interventions+require+a+tailor-made+approach:+Commentary+on+McDaniel+and+Bugg.">Memory training interventions require a tailor-made approach: Commentary on McDaniel and Bugg.</a> Journal of Applied Research in Memory and Cognition. , (2012).</li><li>Sternberg, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Memory-scanning:+mental+processes+revealed+by+reaction-time+experiments.">Memory-scanning: mental processes revealed by reaction-time experiments.</a> American Scientist. , (1969).</li><li>Folstein, M. F., Folstein, S. E., McHugh, P. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Mini-mental+status.+A+practical+method+for+grading+the+cognitive+state+of+patients+for+the+clinician.">Mini-mental status. A practical method for grading the cognitive state of patients for the clinician.</a> Journal of Psychiatric Research. 12 (3), 189-198 (1975).</li><li>Jaeggi, S. M., Buschkuehl, M., Jonides, J., Perrig, W. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Improving+fluid+intelligence+with+training+on+working+memory.">Improving fluid intelligence with training on working memory.</a> Proceedings of the National Academy of Sciences of the United States of America. , (2008).</li><li>Bolger, N., Laurenceau, J. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Methodology in the Social Sciences. , (2013).</li><li>Kwok, O. 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Les auteurs n’ont rien à divulguer.

Dans l’étude présentée ici, nous avons étudié si les personnes âgées pourraient bénéficier d’une formation sur la mémoire de travail et si elle est liée au niveau initial de leur cognition de base. Nous avons utilisé une tâche n-back comme une intervention expérimentale et la capacité de mémoire de travail (mesurée avec la tâche OSPAN) a été la méthode pour sonder le niveau initial des participants de fonctionnement intellectuel. Nous avions deux étapes cruciales dans le protocole. Le premier et...

Dans de nombreuses études sur les formations cognitives, la double tâche n-back est utilisée comme méthode de formation de la mémoire de travail (WM). WM est une cible commune des interventions cognitives en raison de son importance pour d’autres fonctions intellectuelles de niveau supérieur1. Toutefois, l’efficacité d’une telle formation et son potentiel de création d’une amélioration plus générale de la cognition, a fait l’objet de vifs débats (pour la méta-analyse,voir 2,3,4,5,6,7,14 et pour les revues, voir4,8,9,10,11,12,13). Alors que certains chercheurs affirment que « ... il n’y avait aucune preuve convaincante de la généralisation de la formation à la mémoire de travail à d’autres compétences''4, d’autres présentent des données méta-analytiques, qui montrent des effets très significatifs de la formation WM2,3,5,6,11. Le problème distinct est l’efficacité des AMM dans la population âgée. Plusieurs études de formation wm ont rapporté de plus grands avantages chez les jeunes adultes par rapportaux personnes âgées 15,16,17,18,19,20, tandis que d’autres montrent que des effets similaires peuvent être observés dans les deux groupes d’âge21,22,23,24,25.
Divers éléments sont censés prévoir les avantages de la formation à la mémoire26. Certains de ces facteurs semblent être des modérateurs potentiels de l’efficacité de la formation wm21. La capacité mentale, décrite comme la capacité cognitive de base ou la ressource cognitive générale, semble être l’un des choix les plus forts pour ce poste. Afin d’évaluer le rôle du niveau intellectuel initial, nous mettons un accent particulier (la méthode décrite ici) sur la mesure de la capacité cognitive avant d’appliquer un régime de formation. Il a été dicté par les données montrant que les participants, qui sont caractérisés par une capacité cognitive plus élevée au début de la formation, ont obtenu des résultats de formation sensiblement meilleurs par rapport à ceux ayant des niveaux inférieurs de fonction cognitive initiale27. Un phénomène similaire est observé dans la recherche éducative, où il est appelé l’effet Matthew28, une observation que les personnes ayant initialement de meilleures compétences s’améliorent encore plus par rapport à ceux avec un niveau préliminaire inférieur de capacité en question.
Il est stimulant, cependant, qu’il n’y ait pas eu autant de rapports publiés sur cesujet 21,29. En outre, même les différences individuelles substantielles, en particulier lorsqu’il s’agit de la population âgée, sont souvent laissées sans surveillance lors de l’analyse et de l’interprétationdes données 30. Dans la présente étude, nous examinons l’impact du niveau initial de capacité de mémoire de travail sur le succès de la formation wm dans le groupe des personnes âgées en bonne santé. Afin de maintenir tous les éléments des régimes de formation aussi semblables que possible entre les groupes expérimentaux et de contrôle, nous avons utilisé une conception active de groupe témoin. Par conséquent, le contenu de formation (WM versus mémoire sémantique) est resté le seul facteur crucial déterminant la différence attendue dans les résultats de formation. Les deux groupes ont effectué des formations informatisées à domicile. Les membres du groupe expérimental ont été affectés à un programme de formation adaptatif à deux dos et à un groupe témoin actif formé à une tâche basée sur un quiz de mémoire sémantique. Nouveau dans l’approche ici est l’accent mis sur l’évaluation initiale du niveau cognitif des participants en évaluant leur capacité de mémoire de travail (WMC). En outre, la méthode d’évaluation du niveau wmc initial que nous présentons dans cet article s’est avérée être un outil efficace pour distinguer les personnes qui réussiront et ne réussiront pas au cours de la formation ultérieure sur la mémoire de travail. Nous avons déjà décrit et publié les résultats de cette étude44. Par conséquent, dans cet article, nous nous concentrons sur une description détaillée du protocole que nous avons utilisé.

<table border="0" cellpadding="0" cellspacing="0" style="width:976px;" width="976">
	<tbody>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">GEx</td>
			<td style="width:121px;">n/a</td>
			<td style="width:289px;">authorial online platform: 
			used for N-back training, Quiz</td>
			<td style="width:349px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">IBM SPSS Statistics 26.0</td>
			<td style="width:121px;">IBM Corporation</td>
			<td style="width:289px;">SPSS software was used to compute statistical analysis.</td>
			<td style="width:349px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">Inquisit version 4.0.8.0</td>
			<td style="width:121px;">Millisecond Software</td>
			<td style="width:289px;">software: tool for designing and administering experiments 
			used for: The Sternberg Task, The Linear Syllogism Task and presenting the instructions for baseline EEG recording</td>
			<td style="width:349px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">MATLAB R2018b</td>
			<td style="width:121px;">The MathWorks, Inc</td>
			<td style="width:289px;">MATLAB software was used to compute statistics and to export databases and&#160; visualisation of the results</td>
			<td style="width:349px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">PsychoPy version 2 v.1.83.04</td>
			<td style="width:121px;">Jonathan Peirce; supported by University of Nottingham</td>
			<td style="width:289px;">open-source software 
			used for: Go/no Go Task, The Switching Task, Running Memory Span Taskckage based on Python</td>
			<td style="width:349px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">Sublime Text (version 2.0.2)</td>
			<td style="width:121px;">n/a</td>
			<td style="width:289px;">open-source software: HTML editor 
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working memory training for older participants: a control group training regimen and initial intellectual functioning assessment

L’efficacité des interventions de formation cognitive fait récemment l’objet de vifs débats. Il n’y a pas de consensus sur le type de régime de formation le plus efficace. De plus, les caractéristiques individuelles en tant que prédicteurs des résultats de la formation sont encore à l’étude. Dans cet article, nous montrons la tentative d’aborder cette question en examinant non seulement l’impact de la formation sur la mémoire de travail (WM) sur l’efficacité cognitive chez les personnes âgées, mais aussi l’influence de la capacité initiale des AMM (WMC) sur les résultats de la formation. Nous décrivons en détail comment effectuer 5 semaines d’une formation adaptative à double dos avec un groupe de contrôle actif (quiz mémoire). Nous nous concentrons ici sur les aspects techniques de la formation ainsi que sur l’évaluation initiale du WMC des participants. L’évaluation de la performance avant et après l’entraînement d’autres dimensions cognitives était basée sur les résultats des tests de mise à jour de la mémoire, d’inhibition, de déplacement de l’attention, de mémoire à court terme (STM) et de raisonnement. Nous avons constaté que le niveau initial de WMC prédit l’efficacité de l’intervention de formation n-back. Nous avons également remarqué l’amélioration post-formation dans presque tous les aspects du fonctionnement cognitif que nous avons mesurés, mais ces effets étaient pour la plupart indépendants de l’intervention.

Effets liés à la formation
85 sujets ont participé à l’étude (29 étaient des hommes) et ils avaient en moyenne 66,7 ans. En raison de problèmes techniques, les données d’un participant au groupe de formation n-back n’ont pas été enregistrées. Enfin, les données de 43 participants au groupe de formation n-back et de 42 membres du groupe de formation Quiz ont été analysées. L’analyse multiva...

Watch this Scientific Journal Video about Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment at JoVE.com

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Une intervention de formation cognitive dans la population âgée ainsi que l’évaluation des capacités cognitives de pré-formation est présentée. Nous montrons deux versions de la formation - le contrôle expérimental et actif - et démontrons leurs effets sur la gamme des tests cognitifs.

Formation sur la mémoire de travail pour les participants plus âgés : un régime de formation du groupe témoin et une évaluation initiale du fonctionnement intellectuel

The efficacy of cognitive training interventions is recently highly debated. There is no consensus on what kind of training regimen is the most effective. ...

working-memory-training-for-older-participants-control-group-training

Research

JoVE Journal

Behavior

4.5K vues.  SWPS University of Social Sciences and Humanities. Une intervention de formation cognitive dans la population âgée ainsi que l’évaluation des capacités cognitives de pré-formation est présentée. Nous montrons deux versions de la formation - le contrôle expérimental et actif - et démontrons leurs effets sur la gamme des tests cognitifs.

Vidéo: Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Training Synesthetic Letter-color Associations by Reading in Color

Synesthesia is a rare condition in which a stimulus from one modality automatically and consistently triggers unusual sensations in the same and/or other modalities. A relatively common and well-studied type is grapheme-color synesthesia, defined as the consistent experience of color when viewing, hearing and thinking about letters, words and numbers. We describe our method for investigating to what extent synesthetic associations between letters and colors can be learned by reading in color in nonsynesthetes. Reading in color is a special method for training associations in the sense that the associations are learned implicitly while the reader reads text as he or she normally would and it does not require explicit computer-directed training methods. In this protocol, participants are given specially prepared books to read in which four high-frequency letters are paired with four high-frequency colors. Participants receive unique sets of letter-color pairs based on their pre-existing preferences for colored letters. A modified Stroop task is administered before and after reading in order to test for learned letter-color associations and changes in brain activation. In addition to objective testing, a reading experience questionnaire is administered that is designed to probe for differences in subjective experience. A subset of questions may predict how well an individual learned the associations from reading in color. Importantly, we are not claiming that this method will cause each individual to develop grapheme-color synesthesia, only that it is possible for certain individuals to form letter-color associations by reading in color and these associations are similar in some aspects to those seen in developmental grapheme-color synesthetes. The method is quite flexible and can be used to investigate different aspects and outcomes of training synesthetic associations, including learning-induced changes in brain function and structure.

Reading in color is a new method for training letter-color associations that are typically found only in grapheme-color synesthetes. It involves an implicit form of training that has potential for long-term associative training methods&#160;because the training is a byproduct of reading and any text can be colored.

Formation Associations Synesthetic Lettre de couleur en lisant en couleur

Synesthesia is a rare condition in which a stimulus from one modality automatically and consistently triggers unusual sensations in the same and/or other ...

Recherche

Sciences du comportement

A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions

Goal-directed behavior is often impaired by interference from the external environment, either in the form of distraction by irrelevant information that one attempts to ignore, or by interrupting information that demands attention as part of another (secondary) task goal. Both forms of external interference have been shown to detrimentally impact the ability to maintain information in working memory (WM). Emerging evidence suggests that these different types of external interference exert different effects on behavior and may be mediated by distinct neural mechanisms. Better characterizing the distinct neuro-behavioral impact of irrelevant distractions versus attended interruptions is essential for advancing an understanding of top-down attention, resolution of external interference, and how these abilities become degraded in healthy aging and in neuropsychiatric conditions. This manuscript describes a novel cognitive paradigm developed the Gazzaley lab that has now been modified into several distinct versions used to elucidate behavioral and neural correlates of interference, by to-be-ignored distractors versus to-be-attended interruptors. Details are provided on variants of this paradigm for investigating interference in visual and auditory modalities, at multiple levels of stimulus complexity, and with experimental timing optimized for electroencephalography (EEG) or functional magnetic resonance imaging (fMRI) studies. In addition, data from younger and older adult participants obtained using this paradigm is reviewed and discussed in the context of its relationship with the broader literatures on external interference and age-related neuro-behavioral changes in resolving interference in working memory.

A novel cognitive paradigm is developed to elucidate behavioral and neural correlates of interference by to-be-ignored distractors versus interference by to-be-attended interruptors during a working memory task. In this manuscript, several variants of this paradigm are detailed, and data obtained with this paradigm in younger/older adult participants is reviewed.

Un paradigme cognitif chargé d&#39;enquêter sur l&#39;ingérence dans la mémoire de travail par des distractions et interruptions

Goal-directed behavior is often impaired by interference from the external environment, either in the form of distraction by irrelevant information that ...

Vision Training Methods for Sports Concussion Mitigation and Management

There is emerging evidence supporting the use vision training, including light board training tools, as a concussion baseline and neuro-diagnostic tool and potentially as a supportive component to concussion prevention strategies. This paper is focused on providing detailed methods for select vision training tools and reporting normative data for comparison when vision training is a part of a sports management program. The overall program includes standard vision training methods including tachistoscope, Brock&#8217;s string, and strobe glasses, as well as specialized light board training algorithms. Stereopsis is measured as a means to monitor vision training affects. In addition, quantitative results for vision training methods as well as baseline and post-testing *A and Reaction Test measures with progressive scores are reported. Collegiate athletes consistently improve after six weeks of training in their stereopsis, *A and Reaction Test scores. When vision training is initiated as a team wide exercise, the incidence of concussion decreases in players who participate in training compared to players who do not receive the vision training. Vision training produces functional and performance changes that, when monitored, can be used to assess the success of the vision training and can be initiated as part of a sports medical intervention for concussion prevention.

This paper describes a protocol to conduct, quantitatively monitor, and assess the success of vision training initiated as part of a sports medical management program including intervention for concussion prevention and performance enhancement.

Vision Méthodes de formation pour Sports commotion atténuation et la gestion

There is emerging evidence supporting the use vision training, including light board training tools, as a concussion baseline and neuro-diagnostic tool ...

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Shuttle-box avoidance learning is a well-established method in behavioral neuroscience and experimental setups were traditionally custom-made; the necessary equipment is now available by several commercial companies. This protocol provides a detailed description of a two-way shuttle-box avoidance learning paradigm in rodents (here Mongolian gerbils; Meriones unguiculatus) in combination with site-specific electrical intracortical microstimulation (ICMS) and simultaneous chronical electrophysiological in vivo recordings. The detailed protocol is applicable to study multiple aspects of learning behavior and perception in different rodent species.
Site-specific ICMS of auditory cortical circuits as conditioned stimuli here is used as a tool to test the perceptual relevance of specific afferent, efferent and intracortical connections. Distinct activation patterns can be evoked by using different stimulation electrode arrays for local, layer-dependent ICMS or distant ICMS sites. Utilizing behavioral signal detection analysis it can be determined which stimulation strategy is most effective for eliciting a behaviorally detectable and salient signal. Further, parallel multichannel-recordings using different electrode designs (surface electrodes, depth electrodes, etc.) allow for investigating neuronal observables over the time course of such learning processes. It will be discussed how changes of the behavioral design can increase the cognitive complexity (e.g. detection, discrimination, reversal learning).

Shuttle-box avoidance learning is well-established in behavioral neuroscience. This protocol describes how shuttle-box learning in rodents can be combined with site-specific electrical intracortical microstimulation (ICMS) and simultaneous chronical in vivo recordings as a tool to study multiple aspects of learning and perception.

Combiné navette-Box formation avec électrophysiologique Cortex enregistrement et la stimulation comme un outil pour étudier perception et l&#39;apprentissage

Shuttle-box avoidance learning is a well-established method in behavioral neuroscience and experimental setups were traditionally custom-made; the ...

Pavlovian Conditioned Approach Training in Rats

Cues that are contingently paired with unconditioned, rewarding stimuli can acquire rewarding properties themselves through a process known as the attribution of incentive salience, or the transformation of neutral stimuli into attractive, &#34;wanted&#39; stimuli capable of motivating behavior. Pavlovian conditioned approach (PCA) develops after the response-independent presentation of a conditioned stimulus (CS; e.g., a lever) that predicts the delivery of an unconditioned stimulus (US; e.g., a food pellet) and can be used to measure incentive salience. During training, three patterns of conditioned responses (CRs) can develop: sign-tracking behavior (CS-directed CR), goal-tracking behavior (US-directed CR), and an intermediate response (both CRs). Sign-trackers attribute incentive salience to reward-related cues and are more vulnerable to cue-induced reinstatement of drug-seeking as well as other addiction-related behaviors, making PCA a potentially valuable procedure for studying addiction vulnerability. Here, we describe materials and methods used to elicit PCA behavior from rats as well as analyze and interpret PCA behavior in individual experiments.

Here, we present a protocol to elicit Pavlovian conditioned approach behavior in rats. This procedure can be used to measure individual differences in the tendency to approach and attribute incentive salience to reward-related cues and investigate addiction vulnerability.

Pavlovien formation d&#39;approche conditionnée chez le rat

Cues that are contingently paired with unconditioned, rewarding stimuli can acquire rewarding properties themselves through a process known as the ...

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children &#8211; Working Memory (CABC-WM)

The Comprehensive Assessment Battery for Children - Working Memory (CABC-WM) is a computer-based battery designed to assess different components of working memory in young school-age children. Working memory deficits have been identified in children with language-based learning disabilities, including dyslexia1,2 and language impairment3,4, but it is not clear whether these children exhibit deficits in subcomponents of working memory, such as visuospatial or phonological working memory. The CABC-WM is administered on a desktop computer with a touchscreen interface and was specifically developed to be engaging and motivating for children. Although the long-term goal of the CABC-WM is to provide individualized working memory profiles in children, the present study focuses on the initial success and utility of the CABC-WM for measuring central executive, visuospatial, phonological loop, and binding constructs in children with typical development. Immediate next steps are to administer the CABC-WM to children with specific language impairment, dyslexia, and comorbid specific language impairment and dyslexia.

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children &amp;#8211; Working Memory (CABC-WM)

Working memory predicts a significant amount of variance for a variety of cognitive tasks, including speaking, reading, and writing. However, few tools are available to assess working memory in children. We present an innovative, computer-based battery that comprehensively assesses different components of working memory in school-age children.

Évaluation de la mémoire de travail chez les enfants: la batterie d&#39;évaluation complète pour les enfants - Mémoire de travail (CABC-WM)

The Comprehensive Assessment Battery for Children - Working Memory (CABC-WM) is a computer-based battery designed to assess different components of ...

Introducing Clicker Training as a Cognitive Enrichment for Laboratory Mice

Establishing new refinement strategies in laboratory animal science is a central goal in fulfilling the requirements of Directive 2010/63/EU. Previous research determined a profound impact of gentle handling protocols on the well-being of laboratory mice. By introducing clicker training to the keeping of mice, not only do we promote the amicable treatment of mice, but we also enable them to experience cognitive enrichment. Clicker training is a form of positive reinforcement training using a conditioned secondary reinforcer, the "click" sound of a clicker, which serves as a time bridge between the strengthened behavior and an upcoming reward. The effective implementation of the clicker training protocol with a cohort of 12 BALB/c inbred mice of each sex proved to be uncomplicated. The mice learned rather quickly when challenged with tasks of the clicker training protocol, and almost all trained mice overcame the challenges they were given (100% of female mice and 83% of male mice). This study has identified that clicker training for mice strongly correlates with reduced fear in the mice during human-mice interactions, as shown by reduced anxiety-related behaviors (e.g., defecation, vocalization, and urination) and fewer depression-like behaviors (e.g., floating). By developing a reliable protocol that can be easily integrated into the daily routine of the keeping of laboratory mice, the lifetime experience of welfare in the mice can be improved substantially.

The development of new refinement strategies for laboratory mice is a challenging task that contributes towards fulfilling the 3R principle. This protocol introduces clicker training as a cognitive enrichment program for laboratory mice.

Présentation de Clicker Training comme un enrichissement cognitif pour souris de laboratoire

Establishing new refinement strategies in laboratory animal science is a central goal in fulfilling the requirements of Directive 2010/63/EU. Previous ...

Reducing State Anxiety Using Working Memory Maintenance

The purpose of this protocol is to explain how to examine the relationship between working memory processes and anxiety by combining the Sternberg Working Memory (WM) and the threat of shock paradigms. In the Sternberg WM paradigm, subjects are required to maintain a series of letters in the WM for a brief interval and respond by identifying whether the position of a given letter in the series matches a numerical prompt. In the threat of shock paradigm, subjects are exposed to alternating blocks where they are either at risk of receiving unpredictable presentations of a mild electric shock or are safe from the shock. Anxiety is probed throughout the safe and threat blocks using the acoustic startle reflex, which is potentiated under threat (Anxiety-Potentiated Startle (APS)). By conducting the Sternberg WM paradigm during the threat of shock and probing the startle response during either the WM maintenance interval or the intertrial interval, it is possible to determine the effect of WM maintenance on APS.

This protocol demonstrates how to measure anxiety-potentiated startle during the Sternberg Working Memory paradigm.

Réduire l&#39;anxiété de l&#39;État à l&#39;aide de la mémoire de travail

The purpose of this protocol is to explain how to examine the relationship between working memory processes and anxiety by combining the Sternberg Working ...

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

Skeletal muscle atrophy, increased adiposity and reduced physical activity are key changes observed after spinal cord injury (SCI) and are associated with numerous cardiometabolic health consequences. These changes are likely to increase the risk of developing chronic secondary conditions and impact the quality of life in persons with SCI. Surface neuromuscular electrical stimulation evoked resistance training (NMES-RT) was developed as a strategy to attenuate the process of skeletal muscle atrophy, decrease ectopic adiposity, improve insulin sensitivity and enhance mitochondrial capacity. However, NMES-RT is limited to only a single muscle group. Involving multiple muscle groups of the lower extremities may maximize the health benefits of training. Functional electrical stimulation-lower extremity cycling (FES-LEC) allows for the activation of 6 muscle groups, which is likely to evoke greater metabolic and cardiovascular adaptation. Appropriate knowledge of the stimulation parameters is key to maximizing the outcomes of electrical stimulation training in persons with SCI. Adopting strategies for long-term use of NMES-RT and FES-LEC during rehabilitation may maintain the integrity of the musculoskeletal system, a pre-requisite for clinical trials aiming to restore walking after injury. The current manuscript presents a combined protocol using NMES-RT prior to FES-LEC. We hypothesize that muscles conditioned for 12 weeks prior to cycling will be capable of generating greater power, cycle against higher resistance and result in greater adaptation in persons with SCI.

Spinal cord injury is a traumatic medical condition that may result in elevated risks of chronic secondary metabolic disorders. Here, we presented a protocol using surface neuromuscular electrical stimulation-resistance training in conjunction with functional electrical stimulation-lower extremities cycling as a strategy to ameliorate several of these medical problems.

Paradigmes de la formation de Stimulation électrique extrémité inférieure après une lésion de la moelle épinière

Skeletal muscle atrophy, increased adiposity and reduced physical activity are key changes observed after spinal cord injury (SCI) and are associated with ...

A Vibrotactile Feedback Device for Seated Balance Assessment and Training

Postural perturbations, motion tracking, and sensory feedback are modern techniques used to challenge, assess, and train upright sitting, respectively. The goal of the developed protocol is to construct and operate a sitting platform that can be passively destabilized while an inertial measurement unit quantifies its motion and vibrating elements deliver tactile feedback to the user. Interchangeable seat attachments alter the stability level of the device to safely challenge sitting balance. A built-in microcontroller allows fine-tuning of the feedback parameters to augment sensory function. Posturographic measures, typical of balance assessment protocols, summarize the motion signals acquired during timed balance trials. No dynamic sitting protocol to date provides variable challenge, quantification, and sensory feedback free of laboratory constraints. Our results demonstrate that non-disabled users of the device exhibit significant changes in posturographic measures when balance difficulty is altered or vibrational feedback provided. The portable, versatile device has potential applications in rehabilitation (following skeletal, muscular, or neurological injury), training (for sports or spatial awareness), entertainment (via virtual or augmented reality), and research (of sitting-related disorders).

A sitting platform has been developed and assembled that passively destabilizes sitting posture in humans. During the user&#39;s stabilizing task, an inertial measurement unit records the device&#39;s motion, and vibrating elements deliver performance-based feedback to the seat. The portable, versatile device may be used in rehabilitation, assessment, and training paradigms.

Un appareil de rétroaction Vibrotactile pour l’évaluation de l’équilibre assis et formation

Postural perturbations, motion tracking, and sensory feedback are modern techniques used to challenge, assess, and train upright sitting, respectively. ...