This protocol can specifically detect calcium-containing nanocrystals in human urine. This technique could potentially be useful to predict early stages of kidney stone formation as well as other diseases associated with crystal urea. Demonstratin
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The objective of this study was to determine whether nanoparticle tracking analysis (NTA) could detect and quantify urinary calcium containing nanocrystals from healthy adults. The findings from the current study suggest NTA could be a potential tool to estimate urinary nanocrystals during kidney stone disease.