W. Harry Feinstone Department of Molecular Microbiology and Immunology
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Epstein-Barr virus BALF1 is a BCL-2-like antagonist of the herpesvirus antiapoptotic BCL-2 proteins.
Journal of virology Mar, 2002 | Pubmed ID: 11836425
Inhibitor specificity of recombinant and endogenous caspase-9.
The Biochemical journal Sep, 2002 | Pubmed ID: 12067274
BCL-2 and BAX protect adult mice from lethal Sindbis virus infection but do not protect spinal cord motor neurons or prevent paralysis.
Journal of virology Oct, 2002 | Pubmed ID: 12239316
Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12381734
Bax, along with lipid conspirators, allows cytochrome c to escape mitochondria.
Molecular cell Nov, 2002 | Pubmed ID: 12453403
BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development.
Developmental cell Apr, 2003 | Pubmed ID: 12689595
Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins.
The Journal of clinical investigation Jul, 2003 | Pubmed ID: 12840065
Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2003 | Pubmed ID: 12960321
Modulation of synaptic transmission by the BCL-2 family protein BCL-xL.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2003 | Pubmed ID: 12968005
Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper.
Molecular biology of the cell Oct, 2003 | Pubmed ID: 14517326
A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures.
Metabolic engineering Oct, 2003 | Pubmed ID: 14642351
Viral modulators of cell death provide new links to old pathways.
Current opinion in cell biology Dec, 2003 | Pubmed ID: 14644194
Regulation of cell death in the lymphoid system by Bcl-2 family proteins.
Acta haematologica , 2004 | Pubmed ID: 14646344
Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold.
Proteins Jan, 2004 | Pubmed ID: 14705031
Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions.
Biotechnology and bioengineering Mar, 2004 | Pubmed ID: 14966800
Viral Bcl-2 homologs and their role in virus replication and associated diseases.
Biochimica et biophysica acta Mar, 2004 | Pubmed ID: 14996505
Neuronal apoptosis pathways in Sindbis virus encephalitis.
Progress in molecular and subcellular biology , 2004 | Pubmed ID: 15171608
BAD is a pro-survival factor prior to activation of its pro-apoptotic function.
The Journal of biological chemistry Oct, 2004 | Pubmed ID: 15231831
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2004 | Pubmed ID: 15342906
Mitochondrial fission proteins regulate programmed cell death in yeast.
Genes & development Nov, 2004 | Pubmed ID: 15520274
Mitochondrial programmed cell death pathways in yeast.
Developmental cell Nov, 2004 | Pubmed ID: 15525523
Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15561723
Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15590628
Modification of professional antigen-presenting cells with small interfering RNA in vivo to enhance cancer vaccine potency.
Cancer research Jan, 2005 | Pubmed ID: 15665308
Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2005 | Pubmed ID: 15728827
Viruses activate a genetically conserved cell death pathway in a unicellular organism.
The Journal of cell biology Aug, 2005 | Pubmed ID: 16061692
Actions of BAX on mitochondrial channel activity and on synaptic transmission.
Antioxidants & redox signaling Sep-Oct, 2005 | Pubmed ID: 16115013
Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures.
Biotechnology and bioengineering Jun, 2006 | Pubmed ID: 16598795
Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2006 | Pubmed ID: 16793892
Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Biotechnology and bioengineering Jul, 2007 | Pubmed ID: 17099908
Upgrading the BCL-2 network.
Nature cell biology Dec, 2006 | Pubmed ID: 17139279
A Bcl-xL timer sets platelet life span.
Cell Mar, 2007 | Pubmed ID: 17382877
A quorum on bacterial programmed cell death.
Molecular cell Nov, 2007 | Pubmed ID: 18042446
Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission.
Journal of neurophysiology Mar, 2008 | Pubmed ID: 18160428
Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels.
The Journal of biological chemistry Mar, 2008 | Pubmed ID: 18171672
Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18250306
Mitochondrial death pathways in yeast and mammalian cells.
Biochimica et biophysica acta Jul, 2008 | Pubmed ID: 18477482
Unravelling the bcl-2 apoptosis code with a simple model system.
PLoS biology Jun, 2008 | Pubmed ID: 18563968
Aven-dependent activation of ATM following DNA damage.
Current biology : CB Jul, 2008 | Pubmed ID: 18571408
Bcl-2 turns deadly.
Nature chemical biology Dec, 2008 | Pubmed ID: 19008882
Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.
The Journal of cell biology Mar, 2009 | Pubmed ID: 19255249
Reliable method for detection of programmed cell death in yeast.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19609767
SnapShot: BCL-2 proteins.
Cell Jul, 2009 | Pubmed ID: 19632186
The apoptosome at high resolution.
Cell Apr, 2010 | Pubmed ID: 20434981
Seizure tests distinguish intermittent fasting from the ketogenic diet.
Epilepsia Aug, 2010 | Pubmed ID: 20477852
Mitochondrial involvement in cell death of non-mammalian eukaryotes.
Biochimica et biophysica acta Apr, 2011 | Pubmed ID: 20950655
Flying to a halt: Drosophila Aven arrests the cell cycle.
Cell cycle (Georgetown, Tex.) May, 2011 | Pubmed ID: 21487234
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.
Nature cell biology Oct, 2011 | Pubmed ID: 21926988
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.
The Journal of cell biology Oct, 2011 | Pubmed ID: 21987637
N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.
Nature neuroscience Apr, 2012 | Pubmed ID: 22366758
Multipolar functions of BCL-2 proteins link energetics to apoptosis.
Trends in cell biology Jun, 2012 | Pubmed ID: 22560661
The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice.
PloS one , 2012 | Pubmed ID: 22984623
A new view of the lethal apoptotic pore.
PLoS biology , 2012 | Pubmed ID: 23049484
Evolution of Bcl-2 homology motifs: homology versus homoplasy.
Trends in cell biology Mar, 2013 | Pubmed ID: 23199982
The N-terminal helix of Bcl-xL targets mitochondria.
Mitochondrion Mar, 2013 | Pubmed ID: 23333404
Unlatched BAX pairs for death.
Cell Jan, 2013 | Pubmed ID: 23374333
Multiple functions of BCL-2 family proteins.
Cold Spring Harbor perspectives in biology Feb, 2013 | Pubmed ID: 23378584
Quantification of genetically controlled cell death in budding yeast.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23733576
Genome-wide consequences of deleting any single gene.
Molecular cell Nov, 2013 | Pubmed ID: 24211263
Cell death in genome evolution.
Seminars in cell & developmental biology Mar, 2015 | Pubmed ID: 25725369
In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity.
Scientific reports Mar, 2015 | Pubmed ID: 25757939
Potent anti-seizure effects of D-leucine.
Neurobiology of disease Oct, 2015 | Pubmed ID: 26054437
Redefining the BH3 Death Domain as a 'Short Linear Motif'.
Trends in biochemical sciences Dec, 2015 | Pubmed ID: 26541461