Thomas Meier

The Role of Dystroglycan and Its Ligands in Physiology and Disease.

Molecular architecture of the undecameric rotor of a bacterial Na+-ATP synthase.

Glucocorticoid-mediated regulation of utrophin levels in human muscle fibers.

Intersubunit bridging by Na+ ions as a rationale for the unusual stability of the c-rings of Na+-translocating F1F0 ATP synthases.

A cellular model for Friedreich Ataxia reveals small-molecule glutathione peroxidase mimetics as novel treatment strategy.

Membrane embedded location of Na+ or H+ binding sites on the rotor ring of F1F0 ATP synthases.

Fourth generation human immunodeficiency virus (HIV) screening assays with an improved sensitivity for p24 antigen close the second diagnostic window in primary HIV infection.

Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140.

Evidence for structural integrity in the undecameric c-rings isolated from sodium ATP synthases.

Complete DNA sequence of the atp operon of the sodium-dependent F1Fo ATP synthase from Ilyobacter tartaricus and identification of the encoded subunits.

Time-resolved microspectrofluorometry and fluorescence lifetime imaging of photosensitizers using picosecond pulsed diode lasers in laser scanning microscopes.

Dissecting dyskeratosis.

Transcriptional activation of the utrophin promoter B by a constitutively active Ets-transcription factor.

Observing membrane protein diffusion at subnanometer resolution.

Genetic interaction between a chaperone of small nucleolar ribonucleoprotein particles and cytosolic serine hydroxymethyltransferase.

Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.

Detection of glucocorticoid-like activity in traditional Chinese medicine used for the treatment of Duchenne muscular dystrophy.

Electrical power fuels rotary ATP synthase.

In vivo kinetics of Cajal body components.

Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins.

Histological parameters for the quantitative assessment of muscular dystrophy in the mdx-mouse.

The many facets of H/ACA ribonucleoproteins.

Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus.

The c15 ring of the Spirulina platensis F-ATP synthase: F1/F0 symmetry mismatch is not obligatory.

Novel cell-penetrating alpha-keto-amide calpain inhibitors as potential treatment for muscular dystrophy.

Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase.

Catalytic and mechanical cycles in F-ATP synthases. Fourth in the Cycles Review Series.

Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.

How a single protein complex accommodates many different H/ACA RNAs.

Treatment with an oral small molecule inhibitor of P selectin (PSI-697) decreases vein wall injury in a rat stenosis model of venous thrombosis.

Structural investigations of the membrane-embedded rotor ring of the F-ATPase from Clostridium paradoxum.

Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrin.

Social structures and social relations--an archaeological and anthropological examination of three early Medieval separate burial sites in Bavaria.

Dynamic association and localization of human H/ACA RNP proteins.

Low-molecular-weight heparin for prevention of restenosis after femoropopliteal percutaneous transluminal angioplasty: a randomized controlled trial.

Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humans.

Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation.

The nucleolar channel system of human endometrium is related to endoplasmic reticulum and R-rings.

Protective effects of Fe-Aox29, a novel antioxidant derived from a molecular combination of Idebenone and vitamin E, in immortalized fibroblasts and fibroblasts from patients with Friedreich Ataxia.

The oligomeric state of c rings from cyanobacterial F-ATP synthases varies from 13 to 15.

Gangrenous Clostridium perfringens infection and subsequent wound management in a rhesus macaque (Macaca mulatta).

A tridecameric c ring of the adenosine triphosphate (ATP) synthase from the thermoalkaliphilic Bacillus sp. strain TA2.A1 facilitates ATP synthesis at low electrochemical proton potential.

Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation.

Quantification, distribution, and possible source of bacterial biofilm in mouse automated watering systems.

An intermediate step in the evolution of ATPases: a hybrid F(0)-V(0) rotor in a bacterial Na(+) F(1)F(0) ATP synthase.

Dose-dependent thrombus resolution due to oral plaminogen activator inhibitor (PAI)-1 inhibition with tiplaxtinin in a rat stenosis model of venous thrombosis.

Nuclear pore complex proteins mark the implantation window in human endometrium.

Probing the rotor subunit interface of the ATP synthase from Ilyobacter tartaricus.

Effect of calpain and proteasome inhibition on Ca2+-dependent proteolysis and muscle histopathology in the mdx mouse.

Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance.

The loss of the snoRNP chaperone Nopp140 from Cajal bodies of patient fibroblasts correlates with the severity of spinal muscular atrophy.

Mammalian animal models for Duchenne muscular dystrophy.

Idebenone: an emerging therapy for Friedreich ataxia.

The c13 ring from a thermoalkaliphilic ATP synthase reveals an extended diameter due to a special structural region.

Localization of Nopp140 within mammalian cells during interphase and mitosis.

SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs.

Nailfold capillaroscopy: Specific features in Fabry disease.

Complete ion-coordination structure in the rotor ring of Na+-dependent F-ATP synthases.

Aging is associated with impaired thrombus resolution in a mouse model of stasis induced thrombosis.

Implants in the esthetic zone.

Pathogenic NAP57 mutations decrease ribonucleoprotein assembly in dyskeratosis congenita.

Omigapil ameliorates the pathology of muscle dystrophy caused by laminin-alpha2 deficiency.

High-resolution structure of the rotor ring of a proton-dependent ATP synthase.

On the structure of the proton-binding site in the F(o) rotor of chloroplast ATP synthases.

Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates.

Structural and energetic basis for H+ versus Na+ binding selectivity in ATP synthase Fo rotors.

Percutaneous balloon fenestration of flow-limiting iatrogenic dissection of the common femoral artery: report of two cases.

Midterm outcome of endovascular repair of ruptured isolated iliac artery aneurysms.

Predictive value of duplex ultrasound for restenosis after renal artery stenting.

A new type of proton coordination in an F(1)F(o)-ATP synthase rotor ring.

A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia.

ATP synthases: cellular nanomotors characterized by LILBID mass spectrometry.

Microscopic rotary mechanism of ion translocation in the F(o) complex of ATP synthases.

The nucleolar channel system reliably marks the midluteal endometrium regardless of fertility status: a fresh look at an old organelle.

Pseudouridylation goes regulatory.

Distant positioning of proteasomal proteolysis relative to actively transcribed genes.

Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA).

Physicochemical and toxicological characterization of a new generic iron sucrose preparation.

Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: results from a 12 month, double-blind, randomized placebo-controlled trial.

Mutations in a helix-1 motif of the ATP synthase c-subunit of Bacillus pseudofirmus OF4 cause functional deficits and changes in the c-ring stability and mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

Swine model for translational research of invasive intracranial monitoring.

Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice.

Draft genome sequence of the thermoalkaliphilic Caldalkalibacillus thermarum strain TA2.A1.

Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study.

A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy.

The interaction of lipid modified pseudopeptides with lipid membranes.

Cell-free expression and assembly of ATP synthase.

Meta-analysis of the prevalence of Leber hereditary optic neuropathy mtDNA mutations in Europe.

A1Ao-ATP synthase of Methanobrevibacter ruminantium couples sodium ions for ATP synthesis under physiological conditions.

It's time to pay attention to the endometrium, including the nucleolar channel system.

Kin encounter rate and inbreeding avoidance in canids.

The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic.

Plasma Homocysteine is Not Related to the Severity of Microangiopathy in Secondary Raynaud Phenomenon.

Massive monoclonal expansion of CD4 T-cells specific for a Mycobacterium tuberculosis ESAT-6 peptide.

The heart in Friedreich ataxia: definition of cardiomyopathy, disease severity, and correlation with neurological symptoms.

Sclerotherapy of lymphatic cysts of the leg with OK-432.

Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation.

Engineering rotor ring stoichiometries in the ATP synthase.

Structural study on the architecture of the bacterial ATP synthase Fo motor.

Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs.

Effects of glucocorticoids and idebenone on respiratory function in patients with duchenne muscular dystrophy.

Quantification of nucleolar channel systems: uniform presence throughout the upper endometrial cavity.

Severity of peripheral arterial disease is associated with aortic pressure augmentation and subendocardial viability ratio.

Effects of idebenone on color vision in patients with leber hereditary optic neuropathy.

Rating disease progression of Friedreich's ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database.

The c-ring stoichiometry of ATP synthase is adapted to cell physiological requirements of alkaliphilic Bacillus pseudofirmus OF4.

A new type of Na(+)-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif.

Reengineered glucose oxidase for amperometric glucose determination in diabetes analytics.

The function of the Na+-driven flagellum of Vibrio cholerae is determined by osmolality and pH.

Increased permeability of cutaneous lymphatic capillaries and enhanced blood flow in psoriatic plaques.

Progesterone Threshold Determines Nucleolar Channel System Formation in Human Endometrium.

The c-ring ion binding site of the ATP synthase from Bacillus pseudofirmus OF4 is adapted to alkaliphilic lifestyle.

Moissanite anvil cell design for Giga-Pascal nuclear magnetic resonance.

Impacts of breeder loss on social structure, reproduction and population growth in a social canid.

Timing the window of implantation by nucleolar channel system prevalence matches the accuracy of the endometrial receptivity array.