Matthew W. Kelley

Knock-in mouse model for resistance to thyroid hormone (RTH): an RTH mutation in the thyroid hormone receptor beta gene disrupts cochlear morphogenesis.

Fibroblast growth factor signaling regulates pillar cell development in the organ of corti.

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.

Determination and commitment of mechanosensory hair cells.

Exposing the roots of hair cell regeneration in the ear.

Planar and vertical signals control cellular differentiation and patterning in the mammalian cochlea.

Analysis of nuclear receptor function in the mouse auditory system.

Cell adhesion molecules during inner ear and hair cell development, including notch and its ligands.

Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase.

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

Cellular growth and rearrangement during the development of the mammalian organ of Corti.

Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene.

From placode to polarization: new tunes in inner ear development.

Math1 regulates development of the sensory epithelium in the mammalian cochlea.

Planar cell polarity and a potential role for a Wnt morphogen gradient in stereociliary bundle orientation in the mammalian inner ear.

Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti.

Hair cell development: commitment through differentiation.

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.

Noncanonical Wnt signaling and neural polarity.

Regulation of cell fate in the sensory epithelia of the inner ear.

Myosin VI and VIIa distribution among inner ear epithelia in diverse fishes.

Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system.

Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairment.

Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea.

Cellular commitment and differentiation in the organ of Corti.

Has hair cell loss MET its match?

Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti.

Leading Wnt down a PCP path: Cthrc1 acts as a coreceptor in the Wnt-PCP pathway.

Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans.

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea.

Myosin II regulates extension, growth and patterning in the mammalian cochlear duct.

Building the world's best hearing aid; regulation of cell fate in the cochlea.

Regulation of cell fate and patterning in the developing mammalian cochlea.

Specification of cell fate in the mammalian cochlea.

Sox2 induces neuronal formation in the developing mammalian cochlea.

Transfection of mouse cochlear explants by electroporation.

CD44 is a marker for the outer pillar cells in the early postnatal mouse inner ear.

Development of tonotopy in the auditory periphery.

Rbpj regulates development of prosensory cells in the mammalian inner ear.

Response to a letter to the editor.

Loss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory function, protein localization, and axon targeting.

Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.

Examining planar cell polarity in the mammalian cochlea.

Otic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathway.

Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis.

Stem cell therapy for the inner ear: recent advances and future directions.

Cytoskeletal changes in actin and microtubules underlie the developing surface mechanical properties of sensory and supporting cells in the mouse cochlea.

Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papilla.

Molecular mechanisms of inner ear development.

Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear.

A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea.

Planar cell polarity in the inner ear.

Fibroblast growth factor receptor 3 regulates microtubule formation and cell surface mechanical properties in the developing organ of Corti.

The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.

Cilia, Wnt signaling, and the cytoskeleton.

Thyroid hormone increases fibroblast growth factor receptor expression and disrupts cell mechanics in the developing organ of corti.

Making sense with thyroid hormone--the role of T(3) in auditory development.

Making connections in the inner ear: recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cells.

Expression of insulin-like growth factor binding proteins during mouse cochlear development.

Expression and function of scleraxis in the developing auditory system.

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.

A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear.

Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea.

Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse.