Psychiatry,
Brudnick Neuropsychiatric Research Institute,
Psychiatry, Brudnick Neuropsychiatric Research Institute
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Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals.
Neurobiology of disease Feb, 2002 | Pubmed ID: 11848682
Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2002 | Pubmed ID: 12019333
Diseases of the mind and brain: Rett's syndrome.
The American journal of psychiatry Jul, 2002 | Pubmed ID: 12091185
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Archives of general psychiatry Aug, 2002 | Pubmed ID: 12150646
Diseases of the mind and brain: Rett's syndrome, part II.
The American journal of psychiatry Aug, 2002 | Pubmed ID: 12153818
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2002 | Pubmed ID: 12432090
The neurobiology of Rett syndrome.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Feb, 2003 | Pubmed ID: 12580340
Clinical experts on Rett disorder.
Pediatric rehabilitation Apr-Jun, 2002 | Pubmed ID: 12596822
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling.
Journal of neurochemistry Sep, 2004 | Pubmed ID: 15312167
Histone methylation at gene promoters is associated with developmental regulation and region-specific expression of ionotropic and metabotropic glutamate receptors in human brain.
Journal of neurochemistry Jul, 2005 | Pubmed ID: 15998284
Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia.
Archives of general psychiatry Aug, 2005 | Pubmed ID: 16061760
Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice.
Journal of neurobiology Mar, 2006 | Pubmed ID: 16408297
Chromatin immunoprecipitation in postmortem brain.
Journal of neuroscience methods Sep, 2006 | Pubmed ID: 16574239
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis.
Learning & memory (Cold Spring Harbor, N.Y.) May-Jun, 2006 | Pubmed ID: 16705139
Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders.
Brain research reviews Sep, 2006 | Pubmed ID: 16759710
Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse.
Biological psychiatry Jul, 2007 | Pubmed ID: 16945350
The molecular pathology of Rett syndrome: synopsis and update.
Neuromolecular medicine , 2006 | Pubmed ID: 17028371
GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia.
PloS one , 2007 | Pubmed ID: 17726539
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.
PloS one , 2007 | Pubmed ID: 17878930
Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2007 | Pubmed ID: 17942719
Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Nov, 2008 | Pubmed ID: 18288092
DNA methylation changes in schizophrenia and bipolar disorder.
Epigenetics : official journal of the DNA Methylation Society Mar-Apr, 2008 | Pubmed ID: 18398310
Isolation of neuronal chromatin from brain tissue.
BMC neuroscience , 2008 | Pubmed ID: 18442397
A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex.
Human molecular genetics Oct, 2008 | Pubmed ID: 18632683
Epigenetic regulation in human brain-focus on histone lysine methylation.
Biological psychiatry Feb, 2009 | Pubmed ID: 18814864
Approaching the molecular pathology of suicide.
Biological psychiatry Oct, 2008 | Pubmed ID: 18926170
Epigenetics in the nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2008 | Pubmed ID: 19005036
Restoring GABAergic signaling and neuronal synchrony in schizophrenia.
The American journal of psychiatry Dec, 2008 | Pubmed ID: 19047328
Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia.
Biological psychiatry Jun, 2009 | Pubmed ID: 19121517
Cingulate white matter neurons in schizophrenia and bipolar disorder.
Biological psychiatry Sep, 2009 | Pubmed ID: 19559403
Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate.
Neuroscience letters Nov, 2009 | Pubmed ID: 19638299
The molecular pathology of schizophrenia--focus on histone and DNA modifications.
Brain research bulletin Sep, 2010 | Pubmed ID: 19729053
rAAV9--a human-derived adeno-associated virus vector for efficient transgene expression in mouse cingulate cortex.
Cold Spring Harbor protocols Apr, 2010 | Pubmed ID: 20360371
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex.
Proceedings of the National Academy of Sciences of the United States of America May, 2010 | Pubmed ID: 20421462
A simple method for improving the specificity of anti-methyl histone antibodies.
Epigenetics : official journal of the DNA Methylation Society Jul, 2010 | Pubmed ID: 20458167
Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2010 | Pubmed ID: 20505083
Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.
The Journal of biological chemistry Sep, 2010 | Pubmed ID: 20592034
RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder.
Autism research : official journal of the International Society for Autism Research Aug, 2010 | Pubmed ID: 20632321
White matter neuron alterations in schizophrenia and related disorders.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience May, 2011 | Pubmed ID: 20691252
Gender-Specific Reduction of Estrogen-Sensitive Small RNA, miR-30b, in Subjects With Schizophrenia.
Schizophrenia bulletin Aug, 2010 | Pubmed ID: 20732949
Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice.
Neuropharmacology Jun, 2011 | Pubmed ID: 20869373
Keep the 'phospho' on MAPK, be happy.
Nature medicine Nov, 2010 | Pubmed ID: 21052065
The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.
PloS one , 2010 | Pubmed ID: 21209826
Epigenetics of schizophrenia.
Current topics in behavioral neurosciences , 2010 | Pubmed ID: 21312415
Balancing histone methylation activities in psychiatric disorders.
Trends in molecular medicine Jul, 2011 | Pubmed ID: 21429800
Advancing drug discovery for schizophrenia.
Annals of the New York Academy of Sciences Oct, 2011 | Pubmed ID: 22032400
Epigenetic Signatures of Autism: Trimethylated H3K4 Landscapes in Prefrontal Neurons.
Archives of general psychiatry Nov, 2011 | Pubmed ID: 22065254
Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease.
Neurobiology of disease Dec, 2011 | Pubmed ID: 22182689
The neuroepigenetics of suicide.
The American journal of psychiatry May, 2013 | Pubmed ID: 23632831
Chromatin-bound RNA and the neurobiology of psychiatric disease.
Neuroscience Apr, 2014 | Pubmed ID: 23831425
Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2013 | Pubmed ID: 23864674
The Genome in Three Dimensions: A New Frontier in Human Brain Research.
Biological psychiatry Aug, 2013 | Pubmed ID: 23958183
Epigenetics and sex differences in the brain: A genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice.
Experimental neurology Jun, 2015 | Pubmed ID: 25131640
Regulation of histone H3K4 methylation in brain development and disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Sep, 2014 | Pubmed ID: 25135975
Analytical tools and current challenges in the modern era of neuroepigenomics.
Nature neuroscience Nov, 2014 | Pubmed ID: 25349914
Epigenetic mechanisms in schizophrenia.
Dialogues in clinical neuroscience Sep, 2014 | Pubmed ID: 25364289
The future of neuroepigenetics in the human brain.
Progress in molecular biology and translational science , 2014 | Pubmed ID: 25410546
A role for noncoding variation in schizophrenia.
Cell reports Nov, 2014 | Pubmed ID: 25453756
Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia.
Schizophrenia research Sep, 2015 | Pubmed ID: 25458568
Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition.
Neuron Dec, 2014 | Pubmed ID: 25467983
Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2015 | Pubmed ID: 25834037
Interneuron epigenomes during the critical period of cortical plasticity: Implications for schizophrenia.
Neurobiology of learning and memory Oct, 2015 | Pubmed ID: 25849095
Cognition and mood-related behaviors in L3mbtl1 null mutant mice.
PloS one , 2015 | Pubmed ID: 25849281
miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement.
BMC medical genomics Mar, 2015 | Pubmed ID: 25889241
Quantifying polymorphism and divergence from epigenetic data: a framework for inferring the action of selection.
Frontiers in genetics , 2015 | Pubmed ID: 26074949
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Neuron Jul, 2015 | Pubmed ID: 26139371
Chemogenetic Inactivation of Dorsal Anterior Cingulate Cortex Neurons Disrupts Attentional Behavior in Mouse.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Mar, 2016 | Pubmed ID: 26224620
DNA methylation levels of α-synuclein intron 1 in the aging brain.
Neurobiology of aging Dec, 2015 | Pubmed ID: 26422361
Epigenetic Basis of Mental Illness.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 10, 2016 | Pubmed ID: 26450593
Pharmacological modulation of astrocytes and the role of cell type-specific histone modifications for the treatment of mood disorders.
Current opinion in pharmacology Feb, 2016 | Pubmed ID: 26515273
CHRNA7 and CHRFAM7A: psychosis and smoking? Blame the neighbors!
The American journal of psychiatry Nov, 2015 | Pubmed ID: 26575444
The PsychENCODE project.
Nature neuroscience Dec, 2015 | Pubmed ID: 26605881
Prefrontal Cortex and Social Cognition in Mouse and Man.
Frontiers in psychology , 2015 | Pubmed ID: 26635701
RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.
PloS one , 2015 | Pubmed ID: 26636579
Back to the past in schizophrenia genomics.
Nature neuroscience Jan, 2016 | Pubmed ID: 26713739
NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure.
Schizophrenia research Feb, 2016 | Pubmed ID: 26776227
Understanding the genetic liability to schizophrenia through the neuroepigenome.
Schizophrenia research 11, 2016 | Pubmed ID: 26827128
Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue.
Biological psychiatry 01, 2017 | Pubmed ID: 27113501
DNA Methylation Signatures of Early Childhood Malnutrition Associated With Impairments in Attention and Cognition.
Biological psychiatry 11, 2016 | Pubmed ID: 27184921
Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.
Biological psychiatry 07, 2016 | Pubmed ID: 27346079
Insulin-like Growth Factor 1 for Healthy Spines and Healthy Minds?
Biological psychiatry 08, 2016 | Pubmed ID: 27468627
Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 12, 2016 | Pubmed ID: 27485686
Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex.
Nature communications 09, 2016 | Pubmed ID: 27597321
Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism.
PLoS biology Sep, 2016 | Pubmed ID: 27685936
Spatial genome organization and cognition.
Nature reviews. Neuroscience 11, 2016 | Pubmed ID: 27708356
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Molecular psychiatry 01, 2018 | Pubmed ID: 28115742
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.
Science (New York, N.Y.) 04, 2017 | Pubmed ID: 28450582
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.
Nature communications 05, 2017 | Pubmed ID: 28485378
Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2.
Biological psychiatry Dec, 2017 | Pubmed ID: 28577753
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Nature genetics Aug, 2017 | Pubmed ID: 28671686
The epigenomics of schizophrenia, in the mouse.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics Sep, 2017 | Pubmed ID: 28699694
Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.
Stem cell reports 08, 2017 | Pubmed ID: 28757163
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects.
Nature neuroscience Sep, 2017 | Pubmed ID: 28783139
Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes.
Scientific reports 03, 2018 | Pubmed ID: 29523860
Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells.
Frontiers in pediatrics , 2018 | Pubmed ID: 29666786
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
American journal of human genetics 06, 2018 | Pubmed ID: 29805045
Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1.
Cell reports 06, 2018 | Pubmed ID: 29898393
Chromosomal Conformations and Epigenomic Regulation in Schizophrenia.
Progress in molecular biology and translational science , 2018 | Pubmed ID: 29933951
Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome.
Nature neuroscience 08, 2018 | Pubmed ID: 30038276
Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.
Nature communications 08, 2018 | Pubmed ID: 30087329
Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders.
Molecular psychiatry Aug, 2018 | Pubmed ID: 30089790
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.
Science (New York, N.Y.) 12, 2018 | Pubmed ID: 30545851
Comprehensive functional genomic resource and integrative model for the human brain.
Science (New York, N.Y.) 12, 2018 | Pubmed ID: 30545857
Epigenetic-genetic chromatin footprinting identifies novel and subject-specific genes active in prefrontal cortex neurons.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 07, 2019 | Pubmed ID: 30970224
Spatial genome exploration in the context of cognitive and neurological disease.
Current opinion in neurobiology 12, 2019 | Pubmed ID: 31255842
Metabolome signature of autism in the human prefrontal cortex.
Communications biology , 2019 | Pubmed ID: 31263778
CRISPR-based functional evaluation of schizophrenia risk variants.
Schizophrenia research 03, 2020 | Pubmed ID: 31277978
In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene.
Nature communications 09, 2019 | Pubmed ID: 31511512
CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.
Scientific data 09, 2019 | Pubmed ID: 31551426
Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia.
Translational psychiatry 10, 2019 | Pubmed ID: 31624234
Special volume: The genomics and epigenomics of schizophrenia.
Schizophrenia research 03, 2020 | Pubmed ID: 31813801
Use of the epigenetic toolbox to contextualize common variants associated with schizophrenia risk .
Dialogues in clinical neuroscience 12, 2019 | Pubmed ID: 31949408
A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons.
Genome medicine 02, 2020 | Pubmed ID: 32075678
Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior.
Nature communications 02, 2020 | Pubmed ID: 32081848
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles.
Nature neuroscience 04, 2020 | Pubmed ID: 32152537
Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells.
Advances in neurobiology , 2020 | Pubmed ID: 32578147
Epigenetic Clocks in Schizophrenia: Promising Biomarkers, Foggy Clockwork.
Biological psychiatry 08, 2020 | Pubmed ID: 32674842
Genotype-phenotype correlation at codon 1740 of SETD2.
American journal of medical genetics. Part A 09, 2020 | Pubmed ID: 32710489
A prefrontal-paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice.
Nature neuroscience 10, 2020 | Pubmed ID: 32868932
Common genetic variation in humans impacts susceptibility to SARS-CoV-2 infection.
bioRxiv : the preprint server for biology Sep, 2020 | Pubmed ID: 32995783
Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome.
Biological psychiatry Jan, 2021 | Pubmed ID: 33131715
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.
Stem cell reports 03, 2021 | Pubmed ID: 33636110
Comprehensive identification of somatic nucleotide variants in human brain tissue.
Genome biology Mar, 2021 | Pubmed ID: 33781308