Howard Hughes Medical Institute,
Department of Biochemistry and Molecular Pharmacology
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Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing.
Molecular cell Nov, 2007 | Pubmed ID: 18042460
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.
The Journal of biological chemistry Mar, 2009 | Pubmed ID: 19144645
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development.
Molecular and cellular biology Apr, 2009 | Pubmed ID: 19223465
Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo.
The Journal of biological chemistry Jun, 2009 | Pubmed ID: 19332550
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.
The Journal of biological chemistry Dec, 2009 | Pubmed ID: 19808676
Chromatin structure and the inheritance of epigenetic information.
Nature reviews. Genetics Apr, 2010 | Pubmed ID: 20300089
Highly compacted chromatin formed in vitro reflects the dynamics of transcription activation in vivo.
Molecular cell Apr, 2010 | Pubmed ID: 20385088
New chaps in the histone chaperone arena.
Genes & development Jul, 2010 | Pubmed ID: 20595228
Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator.
Science (New York, N.Y.) Aug, 2010 | Pubmed ID: 20798317
The program for processing newly synthesized histones H3.1 and H4.
Nature structural & molecular biology Nov, 2010 | Pubmed ID: 20953179
Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage.
Molecular cell Nov, 2010 | Pubmed ID: 21035370
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA.
Genes & development Dec, 2010 | Pubmed ID: 21123648
The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21196496
Histone tails: ideal motifs for probing epigenetics through chemical biology approaches.
Chembiochem : a European journal of chemical biology Jan, 2011 | Pubmed ID: 21243712
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes & development Jan, 2011 | Pubmed ID: 21245167
Epigenetic inheritance: uncontested?
Cell research Mar, 2011 | Pubmed ID: 21321606
Chromatin higher-order structures and gene regulation.
Current opinion in genetics & development Apr, 2011 | Pubmed ID: 21342762
The C-terminal domain of RNA polymerase II is modified by site-specific methylation.
Science (New York, N.Y.) Apr, 2011 | Pubmed ID: 21454787
BRD4 jump-starts transcription after mitotic silencing.
Genome biology Nov, 2011 | Pubmed ID: 22126464
PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes.
Molecular cell Feb, 2012 | Pubmed ID: 22325352
PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription.
Genes & development Feb, 2012 | Pubmed ID: 22345514
Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.
PloS one , 2012 | Pubmed ID: 22363433
EZH2 couples pancreatic regeneration to neoplastic progression.
Genes & development Mar, 2012 | Pubmed ID: 22391448
Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain is required for efficient transcription of heat shock genes.
Molecular and cellular biology Sep, 2012 | Pubmed ID: 22733996
Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator.
Current biology : CB Oct, 2012 | Pubmed ID: 22885060
Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding.
PLoS genetics , 2012 | Pubmed ID: 22952454
Asymmetrically modified nucleosomes.
Cell Sep, 2012 | Pubmed ID: 23021224
SIRT3 functions in the nucleus in the control of stress-related gene expression.
Molecular and cellular biology Dec, 2012 | Pubmed ID: 23045395
The role of PR-Set7 in replication licensing depends on Suv4-20h.
Genes & development Dec, 2012 | Pubmed ID: 23152447
A chromatin link to caste identity in the carpenter ant Camponotus floridanus.
Genome research Mar, 2013 | Pubmed ID: 23212948
SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors.
Genes & development Apr, 2013 | Pubmed ID: 23592795
Histone chaperone FACT action during transcription through chromatin by RNA polymerase II.
Proceedings of the National Academy of Sciences of the United States of America May, 2013 | Pubmed ID: 23610384
Putting a halt on PRC2 in pediatric glioblastoma.
Nature genetics Jun, 2013 | Pubmed ID: 23715325
A double take on bivalent promoters.
Genes & development Jun, 2013 | Pubmed ID: 23788621
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells.
Nature structural & molecular biology Nov, 2013 | Pubmed ID: 24141703
Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
Genes & development Dec, 2013 | Pubmed ID: 24352422
Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.
PLoS biology Dec, 2013 | Pubmed ID: 24358021
Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome.
eLife Dec, 2013 | Pubmed ID: 24368733
Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin.
Molecular cell Jan, 2014 | Pubmed ID: 24374312
Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.
Molecular cell Jan, 2014 | Pubmed ID: 24462204
Erk1/2 activity promotes chromatin features and RNAPII phosphorylation at developmental promoters in mouse ESCs.
Cell Feb, 2014 | Pubmed ID: 24529373
Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication.
Science (New York, N.Y.) Mar, 2014 | Pubmed ID: 24626927
CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.
Genes & development Apr, 2014 | Pubmed ID: 24696455
Chromatin features and the epigenetic regulation of pluripotency states in ESCs.
Development (Cambridge, England) Jun, 2014 | Pubmed ID: 24917497
Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes.
eLife Jul, 2014 | Pubmed ID: 24986859
Eusocial insects as emerging models for behavioural epigenetics.
Nature reviews. Genetics Oct, 2014 | Pubmed ID: 25200663
Epigenetic inheritance: histone bookmarks across generations.
Trends in cell biology Nov, 2014 | Pubmed ID: 25242115
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.
Nature structural & molecular biology Dec, 2014 | Pubmed ID: 25383670
Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers.
The EMBO journal Feb, 2015 | Pubmed ID: 25515659
USP7 cooperates with SCML2 to regulate the activity of PRC1.
Molecular and cellular biology Apr, 2015 | Pubmed ID: 25605328
CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation.
Science (New York, N.Y.) Feb, 2015 | Pubmed ID: 25722416
Cuticular Hydrocarbon Pheromones for Social Behavior and Their Coding in the Ant Antenna.
Cell reports Aug, 2015 | Pubmed ID: 26279569
Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.
Molecular cell Nov, 2015 | Pubmed ID: 26527279
Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus.
Science (New York, N.Y.) Jan, 2016 | Pubmed ID: 26722000
Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nature communications 04, 2016 | Pubmed ID: 27121947
Co-repressor CBFA2T2 regulates pluripotency and germline development.
Nature 06, 2016 | Pubmed ID: 27281218
Chromatin Starts to Come Clean.
Molecular cell 11, 2016 | Pubmed ID: 27814489
RNA Binding to CBP Stimulates Histone Acetylation and Transcription.
Cell Jan, 2017 | Pubmed ID: 28086087
CTCF-mediated topological boundaries during development foster appropriate gene regulation.
Genes & development 12, 2016 | Pubmed ID: 28087711
The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.
The Journal of clinical investigation 03, 2017 | Pubmed ID: 28165338
Chemosensory sensitivity reflects reproductive status in the ant Harpegnathos saltator.
Scientific reports 06, 2017 | Pubmed ID: 28623371
Functional characterization of odorant receptors in the ponerine ant, .
Proceedings of the National Academy of Sciences of the United States of America 08, 2017 | Pubmed ID: 28696298
Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis.
Molecular cell Aug, 2017 | Pubmed ID: 28781233
An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants.
Cell Aug, 2017 | Pubmed ID: 28802043
Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones.
Nature communications Aug, 2017 | Pubmed ID: 28819196
Correction for Lecona et al., "USP7 Cooperates with SCML2 To Regulate the Activity of PRC1".
Molecular and cellular biology 10, 2017 | Pubmed ID: 28900000
Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.
Molecular cell 05, 2018 | Pubmed ID: 29681498
Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.
Molecular cell 05, 2018 | Pubmed ID: 29681499
Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
Molecular cell 06, 2018 | Pubmed ID: 29932905
Chromatin domains rich in inheritance.
Science (New York, N.Y.) 07, 2018 | Pubmed ID: 29976815
Antennal Olfactory Physiology and Behavior of Males of the Ponerine Ant Harpegnathos saltator.
Journal of chemical ecology Nov, 2018 | Pubmed ID: 30191433
Recent Advances in Behavioral (Epi)Genetics in Eusocial Insects.
Annual review of genetics 11, 2018 | Pubmed ID: 30208294
PRC2 is high maintenance.
Genes & development Aug, 2019 | Pubmed ID: 31123062