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Drug Research Program,
Division of Pharmaceutical Chemistry and Technology,
Faculty of Pharmacy,
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy
Ainoleena Turku has not added Biography.
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Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.
BMC structural biology May, 2015 | Pubmed ID: 25957175
Pharmacophore Model To Discover OX1 and OX2 Orexin Receptor Ligands.
Journal of medicinal chemistry Sep, 2016 | Pubmed ID: 27546834
Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation.
Structural dynamics (Melville, N.Y.) May, 2017 | Pubmed ID: 28345008
Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.
PloS one , 2017 | Pubmed ID: 28575023
Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.
PloS one , 2018 | Pubmed ID: 29641588
Azulene-based compounds for targeting orexin receptors.
European journal of medicinal chemistry Sep, 2018 | Pubmed ID: 30077889
Defining Dynamics of Membrane-Bound Pyrophosphatases by Experimental and Computational Single-Molecule FRET.
Methods in enzymology , 2018 | Pubmed ID: 30149870
Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26.
European journal of pharmacology Oct, 2018 | Pubmed ID: 30194937
Structure-Activity Relationships of 1-Benzoylazulenes at the OX and OX Orexin Receptors.
ChemMedChem May, 2019 | Pubmed ID: 30892823
Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor.
Science advances May, 2019 | Pubmed ID: 31131322
University of Helsinki
Keni Vidilaseris*,1,
Niklas G. Johansson*,2,
Ainoleena Turku2,
Alexandros Kiriazis2,
Gustav Boije af Gennäs2,
Jari Yli-Kauhaluoma2,
Henri Xhaard2,
Adrian Goldman1,3
1Research Program in Molecular and Integrative Biosciences, University of Helsinki,
2Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki,
3School of Biomedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds
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