Department of Internal Medicine II,
Division of Cardiology,
Department of Internal Medicine II, Division of Cardiology
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Impact of clopidogrel loading dose on clinical outcome in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis.
Heart (British Cardiac Society) Jan, 2011 | Pubmed ID: 20736210
Interspecies differences in coagulation profile.
Thrombosis and haemostasis Sep, 2008 | Pubmed ID: 18766254
Reproducibility and standardized reporting of the vasodilator-stimulated phosphoprotein phosphorylation assay.
Platelets Nov, 2008 | Pubmed ID: 18979368
Calcium-channel blockers reduce the antiplatelet effect of clopidogrel.
Journal of the American College of Cardiology Nov, 2008 | Pubmed ID: 19007592
Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel.
American heart journal Jan, 2009 | Pubmed ID: 19081411
The effect of antiplatelet drugs clopidogrel and aspirin is less immediately after stent implantation.
Thrombosis research Apr, 2009 | Pubmed ID: 19135705
Cross validation of the Multiple Electrode Aggregometry. A prospective trial in healthy volunteers.
Thrombosis and haemostasis Aug, 2009 | Pubmed ID: 19652892
Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases.
British journal of pharmacology Feb, 2010 | Pubmed ID: 20050853
The aptamer ARC1779 blocks von Willebrand factor-dependent platelet function in patients with thrombotic thrombocytopenic purpura ex vivo.
Transfusion May, 2010 | Pubmed ID: 20070617
An experimental model to study isolated effects of thrombin in vivo.
Thrombosis research Nov, 2010 | Pubmed ID: 20869757
Targeting von Willebrand factor and platelet glycoprotein Ib receptor.
Expert review of cardiovascular therapy Dec, 2010 | Pubmed ID: 21108551
Ticagrelor: from discovery to Phase III clinical trial.
Future cardiology Nov, 2010 | Pubmed ID: 21142630
Addition of omeprazole to dual antiplatelet therapy with clopidogrel plus aspirin lowers the risk of upper gastrointestinal bleeding.
Evidence-based medicine Oct, 2011 | Pubmed ID: 21558563
Thrombin as a multi-functional enzyme. Focus on in vitro and in vivo effects.
Thrombosis and haemostasis Dec, 2011 | Pubmed ID: 21979864
The effect of erythropoietin on platelet and endothelial activation markers: a prospective trial in healthy volunteers.
Platelets , 2012 | Pubmed ID: 22098110
ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2012 | Pubmed ID: 22282355
Continuous thrombin infusion leads to a bleeding phenotype in sheep.
Thrombosis research Jan, 2012 | Pubmed ID: 22289207
Dual non-responsiveness to antiplatelet treatment is a stronger predictor of cardiac adverse events than isolated non-responsiveness to clopidogrel or aspirin.
International journal of cardiology Jul, 2013 | Pubmed ID: 22305813
Effects of prasugrel on platelet inhibition during systemic endotoxaemia: a randomized controlled trial.
Clinical science (London, England : 1979) Nov, 2012 | Pubmed ID: 22646240
Personalized antiplatelet treatment after percutaneous coronary intervention: the MADONNA study.
International journal of cardiology Sep, 2013 | Pubmed ID: 22656044
Why have studies of tailored anti-platelet therapy failed so far?
Thrombosis and haemostasis Oct, 2013 | Pubmed ID: 23884166
Response variability to P2Y12 receptor inhibitors: expectations and reality.
JACC. Cardiovascular interventions Nov, 2013 | Pubmed ID: 24262612
Association between the rs342293 polymorphism and adverse cardiac events in patients undergoing percutaneous coronary intervention.
Thrombosis and haemostasis Jun, 2014 | Pubmed ID: 24652536
[Dual platelet inhibitors in intensive care units].
Medizinische Klinik, Intensivmedizin und Notfallmedizin Sep, 2014 | Pubmed ID: 24986549
Interplay between genetic and clinical variables affecting platelet reactivity and cardiac adverse events in patients undergoing percutaneous coronary intervention.
PloS one , 2014 | Pubmed ID: 25051347
The net clinical benefit of personalized antiplatelet therapy in patients undergoing percutaneous coronary intervention.
Clinical science (London, England : 1979) Jan, 2015 | Pubmed ID: 25124236
How to improve the concept of individualised antiplatelet therapy with P2Y12 receptor inhibitors--is an algorithm the answer?
Thrombosis and haemostasis Jan, 2015 | Pubmed ID: 25231675
Individualising dual antiplatelet therapy after percutaneous coronary intervention: the IDEAL-PCI registry.
BMJ open Oct, 2014 | Pubmed ID: 25361837
Evaluation of clinical risk factors to predict high on-treatment platelet reactivity and outcome in patients with stable coronary artery disease (PREDICT-STABLE).
PloS one , 2015 | Pubmed ID: 25799149
Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention.
European heart journal Jul, 2015 | Pubmed ID: 25896078
Impact of preoperative use of P2Y12 receptor inhibitors on clinical outcomes in cardiac and non-cardiac surgery: A systematic review and meta-analysis.
European heart journal. Acute cardiovascular care Dec, 2017 | Pubmed ID: 25943554
Inter-patient variability of platelet reactivity in patients treated with prasugrel and ticagrelor.
Platelets Jun, 2016 | Pubmed ID: 26555925
Personalized antiplatelet therapy with P2Y12 receptor inhibitors: benefits and pitfalls.
Postepy w kardiologii interwencyjnej = Advances in interventional cardiology , 2015 | Pubmed ID: 26677375
Distribution of clinical events across platelet aggregation values in all-comers treated with prasugrel and ticagrelor.
Vascular pharmacology Apr, 2016 | Pubmed ID: 26804766
Abciximab as a bridging strategy to overcome morphine-prasugrel interaction in STEMI patients.
British journal of clinical pharmacology 11, 2016 | Pubmed ID: 27366874
Association of PCSK9 with platelet reactivity in patients with acute coronary syndrome treated with prasugrel or ticagrelor: The PCSK9-REACT study.
International journal of cardiology Jan, 2017 | Pubmed ID: 27810295
Advocating cardiovascular precision medicine with P2Y12 receptor inhibitors.
European heart journal. Cardiovascular pharmacotherapy 10, 2017 | Pubmed ID: 28204303
Platelets redox balance assessment: Current evidence and methodological considerations.
Vascular pharmacology 08, 2017 | Pubmed ID: 28684282
Interdependence between osteoprotegerin and active von Willebrand factor in long-term cardiovascular mortality prediction in patients undergoing percutaneous coronary intervention.
Thrombosis and haemostasis 08, 2017 | Pubmed ID: 28726980
Thromboembolic Risk, Bleeding Outcomes and Effect of Different Antithrombotic Strategies in Very Elderly Patients With Atrial Fibrillation: A Sub-Analysis From the PREFER in AF (vention o Thromboembolic Events-uropean egistry in trial ibrillation).
Journal of the American Heart Association Jul, 2017 | Pubmed ID: 28736385
Clopidogrel in Critically Ill Patients.
Clinical pharmacology and therapeutics 02, 2018 | Pubmed ID: 28913918
Ticagrelor - toward more efficient platelet inhibition and beyond.
Therapeutics and clinical risk management , 2018 | Pubmed ID: 29398917
Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).
American heart journal 04, 2018 | Pubmed ID: 29653637
Heart failure subtypes and thromboembolic risk in patients with atrial fibrillation: The PREFER in AF - HF substudy.
International journal of cardiology Aug, 2018 | Pubmed ID: 29706429
Assessment of adherence to medication in patients after myocardial infarction treated with percutaneous coronary intervention. Is there a place for newself-reported questionnaires?
Current medical research and opinion 02, 2019 | Pubmed ID: 30091642
Coming Closer to Personalized Medicine in Transcatheter Aortic Valve Replacement.
JACC. Cardiovascular interventions 09, 2018 | Pubmed ID: 30190062
Cangrelor Induces More Potent Platelet Inhibition without Increasing Bleeding in Resuscitated Patients.
Journal of clinical medicine Nov, 2018 | Pubmed ID: 30445678
Switching between P2Y antagonists - From bench to bedside.
Vascular pharmacology 04, 2019 | Pubmed ID: 30685502
Thrombotic and hemorrhagic burden in women: Gender-related issues in the response to antithrombotic therapies.
International journal of cardiology 07, 2019 | Pubmed ID: 30777407
Platelet reactivity patterns in patients treated with dual antiplatelet therapy.
European journal of clinical investigation Mar, 2019 | Pubmed ID: 30882911
Optimal Timing of P2Y12 Inhibitor Loading in Patients Undergoing PCI: A Meta-Analysis.
Thrombosis and haemostasis Jun, 2019 | Pubmed ID: 30919382
Risk factors for thromboembolic and bleeding events in anticoagulated patients with atrial fibrillation: the prospective, multicentre observational PREvention oF thromboembolic events - European Registry in Atrial Fibrillation (PREFER in AF).
BMJ open 03, 2019 | Pubmed ID: 30928922
[Aortic valve disease].
MMW Fortschritte der Medizin 04, 2019 | Pubmed ID: 30937769
Effectiveness of Antiplatelet Drugs Under Therapeutic Hypothermia: A Comprehensive Review.
Clinical pharmacology and therapeutics 11, 2019 | Pubmed ID: 31055838
Incidence, predictors, and prognosis of premature discontinuation or switch of prasugrel or ticagrelor: the ATLANTIS - SWITCH study.
Scientific reports 06, 2019 | Pubmed ID: 31160687
Shedding Light on Long-Term Effects of Early Antiplatelet Strategies After Fibrinolytic Treatment in STEMI.
Journal of the American College of Cardiology 06, 2019 | Pubmed ID: 31171088
Differential Effects of Ticagrelor With or Without Aspirin on Platelet Reactivity and Coagulation Activation: A Randomized Trial in Healthy Volunteers.
Clinical pharmacology and therapeutics 02, 2020 | Pubmed ID: 31442298
Significance of circulating microRNAs in diabetes mellitus type 2 and platelet reactivity: bioinformatic analysis and review.
Cardiovascular diabetology 08, 2019 | Pubmed ID: 31470851
Transcatheter Aortic Valve Replacement Is Associated with Less Oxidative Stress and Faster Recovery of Antioxidant Capacity than Surgical Aortic Valve Replacement.
Journal of clinical medicine Sep, 2019 | Pubmed ID: 31480644
Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.
European heart journal. Cardiovascular pharmacotherapy Jul, 2020 | Pubmed ID: 31504375
Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups.
BMC medicine 11, 2019 | Pubmed ID: 31679516
Bioresorbable Vascular Scaffolds-Dead End or Still a Rough Diamond?
Journal of clinical medicine Dec, 2019 | Pubmed ID: 31817876
Ticagrelor attenuates the increase of extracellular vesicle concentrations in plasma after acute myocardial infarction compared to clopidogrel.
Journal of thrombosis and haemostasis : JTH 03, 2020 | Pubmed ID: 31833175
Stratified Approaches to Antiplatelet Therapies Based on Platelet Reactivity Testing.
Frontiers in cardiovascular medicine , 2019 | Pubmed ID: 31850373
Transcatheter versus surgical aortic valve replacement in low-risk patients: a meta-analysis of randomized trials.
Clinical research in cardiology : official journal of the German Cardiac Society Jun, 2020 | Pubmed ID: 31863174
Sex and gender in cardiovascular medicine: presentation and outcomes of acute coronary syndrome.
European heart journal Apr, 2020 | Pubmed ID: 31876924
Impact of Preadmission Morphine on Reinfarction in Patients With ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention: A Meta-Analysis.
Clinical pharmacology and therapeutics Jul, 2020 | Pubmed ID: 31990051
Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a Joint Position Paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI).
European heart journal. Cardiovascular pharmacotherapy 02, 2020 | Pubmed ID: 32049278
Antithrombotic agents for primary and secondary prevention of cardiovascular events in patients with end-stage renal disease on chronic hemodialysis.
Atherosclerosis 04, 2020 | Pubmed ID: 32126388
Non-Vitamin K Oral Anticoagulants (NOAC) Versus Vitamin K Antagonists (VKA) for Atrial Fibrillation with Elective or Urgent Percutaneous Coronary Intervention: A Meta-Analysis with a Particular Focus on Combination Type.
Journal of clinical medicine Apr, 2020 | Pubmed ID: 32295160
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
Clinical pharmacology and therapeutics May, 2020 | Pubmed ID: 32472697
Inflammatory state does not affect the antiplatelet efficacy of potent P2Y12 inhibitors in ACS.
Platelets Jun, 2020 | Pubmed ID: 32501749
Prediction for Contrast Volume in Transcatheter Aortic Valve Replacement - Important but Modifiable?
Cardiology , 2020 | Pubmed ID: 32506061
Ticagrelor and prasugrel are independent predictors of improved long-term survival in ACS patients.
European journal of clinical investigation Nov, 2020 | Pubmed ID: 32506444
Adaptive development of concomitant secondary mitral and tricuspid regurgitation after transcatheter aortic valve replacement.
European heart journal cardiovascular Imaging Jun, 2020 | Pubmed ID: 32561917
Updated overview of evidence on optimal antithrombotic therapy in patients with atrial fibrillation undergoing percutanous coronary intervention.
Postepy w kardiologii interwencyjnej = Advances in interventional cardiology Jun, 2020 | Pubmed ID: 32636896
von Willebrand Factor Predicts Mortality in ACS Patients Treated with Potent P2Y12 Antagonists and is Inhibited by Aptamer BT200 Ex Vivo.
Thrombosis and haemostasis Sep, 2020 | Pubmed ID: 32679592
Medication adherence and its determinants in patients after myocardial infarction.
Scientific reports 07, 2020 | Pubmed ID: 32694522
Antithrombotic management and outcomes of patients with atrial fibrillation treated with NOACs early at the time of market introduction: Main results from the PREFER in AF Prolongation Registry.
Internal and emergency medicine Sep, 2020 | Pubmed ID: 32955677
Interleukin-6 level is a powerful predictor of long-term cardiovascular mortality in patients with acute coronary syndrome.
Vascular pharmacology Dec, 2020 | Pubmed ID: 33035661
MicroRNAs and Long Noncoding RNAs in Coronary Artery Disease: New and Potential Therapeutic Targets.
Cardiology clinics Nov, 2020 | Pubmed ID: 33036721
MicroRNAs as Biomarkers of Systemic Changes in Response to Endurance Exercise-A Comprehensive Review.
Diagnostics (Basel, Switzerland) Oct, 2020 | Pubmed ID: 33066215
Prolonged antithrombotic therapy in patients after acute coronary syndrome: A critical appraisal of current European Society of Cardiology guidelines.
Cardiology journal , 2020 | Pubmed ID: 33073857
Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample.
Resuscitation Dec, 2020 | Pubmed ID: 33086085
ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors.
Journal of clinical medicine Nov, 2020 | Pubmed ID: 33233425
Editorial: Antithrombotic Treatment in Transcatheter Structural Cardiac Interventions and After Cardiac Device Implantation.
Frontiers in cardiovascular medicine , 2020 | Pubmed ID: 33282921
Right ventricular function and outcome in patients undergoing transcatheter aortic valve replacement.
European heart journal cardiovascular Imaging Dec, 2020 | Pubmed ID: 33377480
Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and the Risk of SARS-CoV-2 Infection or Hospitalization With COVID-19 Disease: A Systematic Review and Meta-Analysis.
American journal of therapeutics Dec, 2020 | Pubmed ID: 33395057
Sex Differences in Treatment and Outcomes in Non-ST-Elevation Acute Coronary Syndrome: A Persistent Disparity.
Circulation. Cardiovascular interventions Jan, 2021 | Pubmed ID: 33430605
Ganesh Gajanan1,
Emmanouil S. Brilakis2,
Jolanta M. Siller-Matula3,4,5,
Ronald L. Zolty1,
Poonam Velagapudi1
1Division of Cardiovascular Medicine, University of Nebraska Medical Center,
2, Minneapolis Heart Institute,
3Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna,
4Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT,
5Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna