Department of Veterinary Clinical Sciences,
College of Veterinary Medicine,
Department of Veterinary Clinical Sciences, College of Veterinary Medicine
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Maximizing the diagnostic utility of endoscopic biopsy in dogs and cats with gastrointestinal disease.
Veterinary journal (London, England : 1997) , | Pubmed ID: 27387727
Hypovitaminosis D is associated with negative outcome in dogs with protein losing enteropathy: a retrospective study of 43 cases.
BMC veterinary research Apr, 2017 | Pubmed ID: 28390394
Randomized, controlled trial evaluating the effect of multi-strain probiotic on the mucosal microbiota in canine idiopathic inflammatory bowel disease.
Gut microbes , | Pubmed ID: 28678609
Pattern-recognition receptors: signaling pathways and dysregulation in canine chronic enteropathies-brief review.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc , | Pubmed ID: 28906208
Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative.
CPT: pharmacometrics & systems pharmacology , | Pubmed ID: 29178333
Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research.
The AAPS journal , | Pubmed ID: 29234895
Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy.
Journal of veterinary internal medicine , | Pubmed ID: 29604114
Interleukin-1β expression is increased in the duodenum of dogs with idiopathic inflammatory bowel disease.
The Veterinary record , | Pubmed ID: 29743297
Genome-wide association studies of inflammatory bowel disease in German shepherd dogs.
PloS one , | Pubmed ID: 30028859
Relationship of the mucosal microbiota to gastrointestinal inflammation and small cell intestinal lymphoma in cats.
Journal of veterinary internal medicine , | Pubmed ID: 30084202
Changes in duodenal CD163-positive cells in dogs with chronic enteropathy after successful treatment.
Innate immunity , | Pubmed ID: 30223681
Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of gastrointestinal stromal tumors of dogs.
Journal of veterinary internal medicine , | Pubmed ID: 30307656
Correlating Gastrointestinal Histopathologic Changes to Clinical Disease Activity in Dogs With Idiopathic Inflammatory Bowel Disease.
Veterinary pathology , | Pubmed ID: 30563436
CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies.
The AAPS journal Apr, 2019 | Pubmed ID: 30963322
Derivation of adult canine intestinal organoids for translational research in gastroenterology.
BMC biology , | Pubmed ID: 30975131
Interleukin-13 and interleukin-33 mRNA are underexpressed in the duodenal mucosa of German Shepherd dogs with chronic enteropathy.
Journal of veterinary internal medicine , | Pubmed ID: 31169944
Indoleamine-pyrrole 2,3-dioxygenase-1 (IDO-1) mRNA is over-expressed in the duodenal mucosa and is negatively correlated with serum tryptophan concentrations in dogs with protein-losing enteropathy.
PloS one , | Pubmed ID: 31181125
The Gut-Brain Axis in Neurodegenerative Diseases and Relevance of the Canine Model: A Review.
Frontiers in aging neuroscience , | Pubmed ID: 31275138
Microbiota-Related Changes in Unconjugated Fecal Bile Acids Are Associated With Naturally Occurring, Insulin-Dependent Diabetes Mellitus in Dogs.
Frontiers in veterinary science , | Pubmed ID: 31316997
Enterocolic increase of cannabinoid receptor type 1 and type 2 and clinical improvement after probiotic administration in dogs with chronic signs of colonic dysmotility without mucosal inflammatory changes.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society , | Pubmed ID: 31495983
Administration of a Synbiotic Containing Does Not Significantly Alter Fecal Microbiota Richness or Diversity in Dogs With and Without Food-Responsive Chronic Enteropathy.
Frontiers in veterinary science , | Pubmed ID: 31552278
Ki-67/CD3 ratio in the diagnosis of chronic inflammatory enteropathy in dogs.
Journal of veterinary internal medicine , | Pubmed ID: 31825538
Glucocorticoid and dietary effects on mucosal microbiota in canine inflammatory bowel disease.
PloS one , | Pubmed ID: 31887117
Apparent total tract digestibility, fecal characteristics, and blood parameters of healthy adult dogs fed high-fat diets.
Journal of animal science , | Pubmed ID: 32047902
Colonic mucosal and serum expression of microRNAs in canine large intestinal inflammatory bowel disease.
BMC veterinary research , | Pubmed ID: 32087719
Recapitulation of the accessible interface of biopsy-derived canine intestinal organoids to study epithelial-luminal interactions.
PloS one , | Pubmed ID: 32302323
Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study.
Obesity (Silver Spring, Md.) , | Pubmed ID: 32573118
Treatment With Hydrolyzed Diet Supplemented With Prebiotics and Glycosaminoglycans Alters Lipid Metabolism in Canine Inflammatory Bowel Disease.
Frontiers in veterinary science , | Pubmed ID: 32851029
Canine Protein Losing Enteropathies and Systemic Complications.
The Veterinary clinics of North America. Small animal practice , | Pubmed ID: 33131913
Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study.
Journal of Alzheimer's disease : JAD , | Pubmed ID: 33252089
An initial genome-wide investigation of protein-losing enteropathy in Gordon setters: Exploratory observations.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire , | Pubmed ID: 33390653
Colonic mucosal and cytobrush sample cytokine mRNA expression in canine inflammatory bowel disease and their correlation with disease activity, endoscopic and histopathologic score.
PloS one , | Pubmed ID: 33471872
Emerging Roles of Urine-Derived Components for the Management of Bladder Cancer: One Man's Trash Is Another Man's Treasure.
Cancers , | Pubmed ID: 33498666
Inflammation, negative affect, and amyloid burden in Alzheimer's disease: Insights from the kynurenine pathway.
Brain, behavior, and immunity , | Pubmed ID: 33775832
Upregulation of signal transducer and activator of transcription 3 in dogs with chronic inflammatory enteropathies.
Journal of veterinary internal medicine , | Pubmed ID: 33955083
Multiomic analysis defines the first microRNA atlas across all small intestinal epithelial lineages and reveals novel markers of almost all major cell types.
American journal of physiology. Gastrointestinal and liver physiology , | Pubmed ID: 34643097
Clinical efficacy of prebiotics and glycosaminoglycans versus placebo In dogs with food responsive enteropathy receiving a hydrolyzed diet: A pilot study.
PloS one , | Pubmed ID: 34673776
Current diagnostics for chronic enteropathies in dogs.
Veterinary clinical pathology , | Pubmed ID: 34699081
Vojtech Gabriel1,
Christopher Zdyrski1,
Dipak K. Sahoo2,
Kimberly Dao3,
Agnes Bourgois-Mochel2,
Todd Atherly3,
Marilyn N. Martinez4,
Donna A. Volpe5,
Jamie Kopper2,
Karin Allenspach2,3,
Jonathan P. Mochel1,3
1Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University,
2Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University,
3, 3D Health Solutions Inc.,
4Office of New Animal Drug Evaluation, Center for Veterinary Medicine, Food and Drug Administration,
5Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration