Christopher K. Glass

Transcriptional activation by NF-kappaB requires multiple coactivators.

Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray.

An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation.

Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway.

Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression.

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

Nuclear receptors versus inflammation: mechanisms of transrepression.

Evidence mandating earlier and more aggressive treatment of hypercholesterolemia.

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.

Deconstructing repression: evolving models of co-repressor action.

Macrophages, inflammation, and insulin resistance.

Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.

Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy.

A global clustering algorithm to identify long intergenic non-coding RNA--with applications in mouse macrophages.

PPARs and lipid ligands in inflammation and metabolism.

Microglial cell origin and phenotypes in health and disease.

Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β.

Regulation of microglia activation and deactivation by nuclear receptors.

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate.

Signaling by nuclear receptors.

A combined omics study on activated macrophages--enhanced role of STATs in apoptosis, immunity and lipid metabolism.

Vespucci: a system for building annotated databases of nascent transcripts.

Epigenomics of macrophages.

The choreography of neuroinflammation in Huntington's disease.

Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.

Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity.

Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies.

Nature and nurture of tissue-specific macrophage phenotypes.

Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages.

SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer.

Transcriptional and epigenetic regulation of macrophages in atherosclerosis.

Brain cell type-specific enhancer-promoter interactome maps and diseaserisk association.

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.

deficient microglia exhibit a premature aging transcriptome.

Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung.

Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression.

Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.

ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis.

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.

Monocyte Regulation in Homeostasis and Malignancy.

Nuclei isolation of multiple brain cell types for omics interrogation.

Heterogeneity of HSCs in a Mouse Model of NASH.

PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.

A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition.

Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease.

Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs.

Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response.

The Lung Microenvironment Instructs Gene Transcription in Neonatal and Adult Alveolar Macrophages.

DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages.

Shared Mechanisms between Cardiovascular Disease and NAFLD.

Human microglia phenotypes in the brain associated with HIV infection.

Microglia states and nomenclature: A field at its crossroads.

CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy.

A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice.

Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis.

Deep learning predicts the impact of regulatory variants on cell-type-specific enhancers in the brain.

Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages.

Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity.

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation.

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.

A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation.

Gene expression and chromatin conformation of microglia in virally suppressed people with HIV.

Interpretation of Neurodegenerative GWAS Risk Alleles in Microglia and their Interplay with Other Cell Types.

Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain.

Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2.