Monash Institute of Pharmaceutical Sciences,
Drug Discovery Biology Theme,
Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences
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Caveolin-1 inhibits breast cancer growth and metastasis.
Oncogene Oct, 2004 | Pubmed ID: 15334058
Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.
Molecular cancer research : MCR Jan, 2005 | Pubmed ID: 15671244
Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone.
Breast cancer research : BCR , 2006 | Pubmed ID: 16608535
Enhanced replication of simian immunodeficiency virus adjacent to catecholaminergic varicosities in primate lymph nodes.
Journal of virology May, 2006 | Pubmed ID: 16611891
Stress-induced remodeling of lymphoid innervation.
Brain, behavior, and immunity Jan, 2008 | Pubmed ID: 17697764
Social stress enhances sympathetic innervation of primate lymph nodes: mechanisms and implications for viral pathogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2007 | Pubmed ID: 17699667
SIV infection decreases sympathetic innervation of primate lymph nodes: the role of neurotrophins.
Brain, behavior, and immunity Feb, 2008 | Pubmed ID: 17870298
Social temperament and lymph node innervation.
Brain, behavior, and immunity Jul, 2008 | Pubmed ID: 18068331
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers.
Brain, behavior, and immunity Oct, 2009 | Pubmed ID: 19389469
Stromal cell expression of caveolin-1 predicts outcome in breast cancer.
The American journal of pathology Jun, 2009 | Pubmed ID: 19411449
Computational identification of gene-social environment interaction at the human IL6 locus.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20176930
The sympathetic nervous system induces a metastatic switch in primary breast cancer.
Cancer research Sep, 2010 | Pubmed ID: 20823155
Modulation of protein tyrosine phosphorylation in gastric mucosa during re-epithelization processes.
World journal of biological chemistry Nov, 2010 | Pubmed ID: 21537468
Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling.
Brain, behavior, and immunity May, 2012 | Pubmed ID: 22306453
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium.
Cancer cell Feb, 2012 | Pubmed ID: 22340592
Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.
Cancer research Aug, 2012 | Pubmed ID: 22751463
PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases.
Journal of controlled release : official journal of the Controlled Release Society Jun, 2013 | Pubmed ID: 23499718
Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches.
Best practice & research. Clinical anaesthesiology Dec, 2013 | Pubmed ID: 24267548
Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment.
Brain, behavior, and immunity Aug, 2014 | Pubmed ID: 24650449
α2-Adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression.
Psychoneuroendocrinology Jan, 2015 | Pubmed ID: 25462899
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumour-burdened lymph nodes after intravenous and subcutaneous administration in rats.
Molecular pharmaceutics Dec, 2014 | Pubmed ID: 25485615
Neural Regulation of Pancreatic Cancer: A Novel Target for Intervention.
Cancers Jul, 2015 | Pubmed ID: 26193320
The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2016 | Pubmed ID: 26578688
β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion.
Breast cancer research : BCR Nov, 2015 | Pubmed ID: 26607426
Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination.
Nature communications , 2016 | Pubmed ID: 26925549
β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer.
Brain, behavior, and immunity Oct, 2016 | Pubmed ID: 27321906
Neural regulation of cancer: from mechanobiology to inflammation.
Clinical & translational immunology May, 2016 | Pubmed ID: 27350878
β-Adrenergic-stimulated macrophages: Comprehensive localization in the M1-M2 spectrum.
Brain, behavior, and immunity Oct, 2016 | Pubmed ID: 27485040
Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature.
Molecular & cellular oncology Jul, 2016 | Pubmed ID: 27652324
Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer Cells.
Metabolites Sep, 2016 | Pubmed ID: 27669323
Cancer cells become less deformable and more invasive with activation of β-adrenergic signaling.
Journal of cell science 12, 2016 | Pubmed ID: 27875276
Implicating anaesthesia and the perioperative period in cancer recurrence and metastasis.
Clinical & experimental metastasis 04, 2018 | Pubmed ID: 28894976
β-Adrenergic Signaling Impairs Antitumor CD8 T-cell Responses to B-cell Lymphoma Immunotherapy.
Cancer immunology research 01, 2018 | Pubmed ID: 29146881
Perioperative events influence cancer recurrence risk after surgery.
Nature reviews. Clinical oncology 04, 2018 | Pubmed ID: 29283170
Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.
Cancer research 06, 2018 | Pubmed ID: 29510994
Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation.
BMC cancer May, 2018 | Pubmed ID: 29793446
Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET.
iScience Aug, 2018 | Pubmed ID: 30240618
Circulating epinephrine is not required for chronic stress to enhance metastasis.
Psychoneuroendocrinology 01, 2019 | Pubmed ID: 30253326
Stress hormone signaling through β-adrenergic receptors regulates macrophage mechanotype and function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 03, 2019 | Pubmed ID: 30509116
Low dose aspirin blocks breast cancer-induced cognitive impairment in mice.
PloS one , 2018 | Pubmed ID: 30532184
Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases.
Theranostics , 2019 | Pubmed ID: 30867822
Complex Formation between VEGFR2 and the β-Adrenoceptor.
Cell chemical biology 06, 2019 | Pubmed ID: 30956148
Interaction of neurotransmitters and neurochemicals with lymphocytes.
Journal of neuroimmunology 07, 2019 | Pubmed ID: 30999218
C/EBPβ regulates the M2 transcriptome in β-adrenergic-stimulated macrophages.
Brain, behavior, and immunity 08, 2019 | Pubmed ID: 31132458
β-Adrenergic receptor expression is associated with biomarkers of tumor immunity and predicts poor prognosis in estrogen receptor-negative breast cancer.
Breast cancer research and treatment Oct, 2019 | Pubmed ID: 31290053
Preoperative β-Blockade with Propranolol Reduces Biomarkers of Metastasis in Breast Cancer: A Phase II Randomized Trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 04, 2020 | Pubmed ID: 31754048
Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis.
Cancer research 03, 2020 | Pubmed ID: 31941699
Application of a Sulfoxonium Ylide Electrophile to Generate Cathepsin X-Selective Activity-Based Probes.
ACS chemical biology 03, 2020 | Pubmed ID: 32022538
Roadmap for the Emerging Field of Cancer Neuroscience.
Cell 04, 2020 | Pubmed ID: 32302564
Smoking and Colorectal Cancer Risk, Overall and by Molecular Subtypes: A Meta-Analysis.
The American journal of gastroenterology 12, 2020 | Pubmed ID: 32773458
Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study.
BMC medicine 09, 2020 | Pubmed ID: 32900363
Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome.
BMC biology 11, 2020 | Pubmed ID: 33158447
Trisulfide-Bearing PEG Brush Polymers Donate Hydrogen Sulfide and Ameliorate Cellular Oxidative Stress.
Biomacromolecules 12, 2020 | Pubmed ID: 33210534
Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model.
Biomaterials science Feb, 2021 | Pubmed ID: 33231231
Publisher Correction: Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome.
BMC biology Dec, 2020 | Pubmed ID: 33327952
The Anti-Inflammatory Drug Aspirin Does Not Protect Against Chemotherapy-Induced Memory Impairment by Paclitaxel in Mice.
Frontiers in oncology , 2020 | Pubmed ID: 33381448
Beta-adrenergic blockade blunts inflammatory and antiviral/antibody gene expression responses to acute psychosocial stress.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 03, 2021 | Pubmed ID: 33452438
Physical activity modulates mononuclear phagocytes in mammary tissue and inhibits tumor growth in mice.
PeerJ , 2021 | Pubmed ID: 33552733
Carvedilol blocks neural regulation of breast cancer progression in vivo and is associated with reduced breast cancer mortality in patients.
European journal of cancer (Oxford, England : 1990) Apr, 2021 | Pubmed ID: 33639323
Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses.
Immunity Apr, 2021 | Pubmed ID: 33915109
Julia A. Dubowitz1,2,3,
Fabian Jost-Brinkmann1,4,5,
Alexandra I. Ziegler1,
Ryan D. Gillis1,
Bernhard Riedel1,2,3,6,
Erica K. Sloan1,2
1Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University,
2Department of Anaesthesia, Division of Cancer Surgery, Peter MacCallum Cancer Centre,
3Department of Critical Care, Melbourne Medical School, University of Melbourne,
4Medical Department, Division of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin,
5, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health,
6Sir Peter MacCallum Department of Oncology, University of Melbourne