Results: Differentiation of IMOP Cells into Inner Ear Sensory Epithelia and Spiral Ganglion Neurons
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Conclusion
Trascrizione
The overall goal of this procedure is to differentiate immortalized multipotent otic progenitor cells into inner ear cell types. So this method can help us address key questions in auditory regeneration, such as how otic progenitors can become coc
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The current protocols to maintain immortalized multipotent otic progenitor (iMOP) cells and otic differentiation are described. Culture conditions and molecular markers that indicate differentiation into sensory epithelia and spiral ganglion neurons (SGN) are highlighted.