Results: High-throughput, Multiplex CSF Assay for Quantification of Neurodegeneration Markers and Detection of ApoE Isoforms
6:17
Conclusion
Trascrizione
The overall goal of this method is to quickly and affordably quantitate multiple biomarkers in cerebrospinal fluid, or CSF, to assess their use towards diagnosis and treatment monitoring. This is a new assay that allows us to measure biomarkers th
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We describe a high-throughput, multiplex, and targeted proteomic cerebrospinal fluid (CSF) assay developed with potential for clinical translation. The test can quantitate potential markers and risk factors for neurodegeneration, such as the apolipoprotein E variants (E2, E3 and E4), and measure their allelic expression.