JoVE Journal

Neuroscience

This content is Open Access.

In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation

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05:40 min

September 8th, 2016

September 8th, 2016

8,646 Views

0:05

Title

0:45

Animal Surgery, DNA Injection, and Electroporation

3:18

Post-electroporation

3:55

Results: Representative Results on Transfected Sciatic Nerves

5:17

Conclusion

Trascrizione

Here, we present an in vivo technique for gene transfer to Schwann cells (SCs) in the rodent sciatic nerve. This simple technique is useful for investigating signaling mechanisms involved in the development and maintenance of myelinating SCs.

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