低酸素性ヒト胎盤由来の小細胞外小胞によるマウス血液脳関門の破壊

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05:31 min

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January 26th, 2024

DOI :

10.3791/65867-v

January 26th, 2024

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Hermes Sandoval*¹, José León*¹^,², Felipe Troncoso¹, Valeria de la Hoz³, Aaron Cisterna³^,⁴, Moisés Contreras¹, Fidel O. Castro⁵, Belén Ibañez¹, Jesenia Acurio¹, Carlos Escudero¹^,⁶

¹Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, Chillan, ²Nursery School, Health Faculty, Universidad Santo Tomás, Los Angeles, ³Obstetrics and Gynecology Department, Herminda Martin Clinical Hospital, Chillan, ⁴Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepcion, ⁵Laboratory of Animal Biotechnology, Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepción, Chillan, ⁶Group of Research and Innovation in Vascular Health (GRIVAS Health), Chillan

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JoVE 203

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Introduction

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Isolation of Normoxic and Hypoxic Human Placenta‐Derived Small Extracellular Vesicles for Injection into Mice