Department of Immunology
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Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies.
Journal of neuroimmunology May, 2003 | Pubmed ID: 12742663
The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis.
Journal of neuroimmunology Jul, 2003 | Pubmed ID: 12864987
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis.
The Journal of clinical investigation Aug, 2003 | Pubmed ID: 12925692
Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo.
Glia Dec, 2003 | Pubmed ID: 14603470
Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus.
Journal of neuroimmunology Apr, 2004 | Pubmed ID: 15020075
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) May, 2004 | Pubmed ID: 15100291
Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2005 | Pubmed ID: 16237087
Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules.
Journal of cell science Apr, 2006 | Pubmed ID: 16537647
Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro.
Immunology May, 2007 | Pubmed ID: 17302735
HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation.
Blood Jul, 2007 | Pubmed ID: 17371944
Human CD4+ T cells displaying viral epitopes elicit a functional virus-specific memory CD8+ T cell response.
Journal of immunology (Baltimore, Md. : 1950) May, 2007 | Pubmed ID: 17442927
Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration.
Journal of neuroimmunology Aug, 2007 | Pubmed ID: 17582512
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.
Human immunology Sep, 2007 | Pubmed ID: 17869649
Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels.
The Journal of general virology Oct, 2008 | Pubmed ID: 18796710
Cathepsin G is differentially expressed in primary human antigen-presenting cells.
Cellular immunology , 2009 | Pubmed ID: 19036358
Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs.
Experimental hematology Feb, 2009 | Pubmed ID: 19100676
Detection of aberrant transcription of major histocompatibility complex class II antigen presentation genes in chronic lymphocytic leukaemia identifies HLA-DOA mRNA as a prognostic factor for survival.
British journal of haematology May, 2009 | Pubmed ID: 19245431
Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.
Stroke; a journal of cerebral circulation May, 2009 | Pubmed ID: 19265055
Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R.
Stem cells (Dayton, Ohio) Apr, 2009 | Pubmed ID: 19353519
United Europeans for development of pharmacogenomics in multiple sclerosis network.
Pharmacogenomics May, 2009 | Pubmed ID: 19450134
Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2009 | Pubmed ID: 19542375
Antigen processing and presentation in multiple sclerosis.
Results and problems in cell differentiation , 2010 | Pubmed ID: 19582405
Yersinia enterocolitica targets cells of the innate and adaptive immune system by injection of Yops in a mouse infection model.
PLoS pathogens Aug, 2009 | Pubmed ID: 19680448
Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2009 | Pubmed ID: 19843935
Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis.
Brain : a journal of neurology Dec, 2009 | Pubmed ID: 19933767
Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice.
Biochimie Nov, 2010 | Pubmed ID: 20347002
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May, 2012 | Pubmed ID: 22234339
Cathepsin S dominates autoantigen processing in human thymic dendritic cells.
Journal of autoimmunity Jun, 2012 | Pubmed ID: 22424724
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Blood Nov, 2012 | Pubmed ID: 22976954
Relapsing cerebral aspergilloma associated with pregnancy.
Clinical neurology and neurosurgery Jul, 2013 | Pubmed ID: 23058744
Fine mapping and functional analysis of the multiple sclerosis risk gene CD6.
PloS one , 2013 | Pubmed ID: 23638056
Exploring the MHC-peptide matrix of central tolerance in the human thymus.
Nature communications Jun, 2013 | Pubmed ID: 23783831
Effect of prenatal steroid treatment on the developing immune system.
Journal of molecular medicine (Berlin, Germany) Jul, 2013 | Pubmed ID: 23851605
Christina Stoeckle1,2,
Ioanna A. Rota1,
Eva Tolosa3,
Christoph Haller4,
Arthur Melms5,
Eleni Adamopoulou1
1Department of General Neurology, Hertie Institute for Clinical Brain Research,
2Institute of Pharmacology, University of Bern,
3Department of Immunology, University Medical Center Hamburg-Eppendorf,
4Department of Thoracic and Cardiovascular Surgery, University Clinic Tuebingen,
5Department of Neurology, University Hospital Erlangen
Fynn Gerlach*,1,
Franziska Möckl*,1,
Dejan Kovacevic1,2,3,
Valerie J. Brock1,
Riekje Winzer4,
Lina Meyer2,3,
David Lohr2,3,
Lena-Marie Woelk2,3,
Eva Tolosa4,
René Werner2,3,
Björn-Philipp Diercks1
1The Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Centre Hamburg-Eppendorf,
2Department of Applied Medical Informatics, University Medical Centre Hamburg-Eppendorf,
3Department of Computational Neuroscience, University Medical Centre Hamburg-Eppendorf,
4Department of Immunology, University Medical Centre Hamburg-Eppendorf
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