Skaggs School of Pharmacy and Pharmaceutical Sciences
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Thymosin beta 4 is dispensable for murine cardiac development and function.
Circulation research Feb, 2012 | Pubmed ID: 22158707
Development of the cardiac conduction system as delineated by minK-lacZ.
Journal of cardiovascular electrophysiology Apr, 2003 | Pubmed ID: 12741710
Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart development.
Gene expression patterns : GEP Dec, 2003 | Pubmed ID: 14643687
Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block.
Cell Apr, 2004 | Pubmed ID: 15109497
T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.
Development (Cambridge, England) Dec, 2006 | Pubmed ID: 17119020
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification.
Cell Dec, 2006 | Pubmed ID: 17123592
Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells.
Developmental biology Apr, 2007 | Pubmed ID: 17258700
Progenitor cells for cardiac repair.
Seminars in cell & developmental biology Feb, 2007 | Pubmed ID: 17321172
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis.
Proceedings of the National Academy of Sciences of the United States of America May, 2007 | Pubmed ID: 17519333
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.
Nature genetics Oct, 2007 | Pubmed ID: 17767158
The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development.
Development (Cambridge, England) Feb, 2008 | Pubmed ID: 18184728
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway.
Cell stem cell Aug, 2007 | Pubmed ID: 18371348
A myocardial lineage derives from Tbx18 epicardial cells.
Nature Jul, 2008 | Pubmed ID: 18480752
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.
The Journal of clinical investigation Aug, 2008 | Pubmed ID: 18636119
A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs.
Nature neuroscience Nov, 2008 | Pubmed ID: 18849985
Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.
Diabetes Sep, 2009 | Pubmed ID: 19502415
Distinct origins and genetic programs of head muscle satellite cells.
Developmental cell Jun, 2009 | Pubmed ID: 19531353
Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.
Circulation Aug, 2009 | Pubmed ID: 19652092
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity.
Development (Cambridge, England) Sep, 2009 | Pubmed ID: 19666821
Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.
Development (Cambridge, England) Dec, 2009 | Pubmed ID: 19906864
Loss of enigma homolog protein results in dilated cardiomyopathy.
Circulation research Aug, 2010 | Pubmed ID: 20538684
Distinction between two populations of islet-1-positive cells in hearts of different murine strains.
Stem cells and development Jun, 2011 | Pubmed ID: 20942609
MicroRNAs in a cardiac loop: progenitor or myocyte?
Developmental cell Dec, 2010 | Pubmed ID: 21145492
Myocardial lineage development.
Circulation research Dec, 2010 | Pubmed ID: 21148449
Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.
Human molecular genetics May, 2011 | Pubmed ID: 21303826
Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis.
Cardiovascular research Jul, 2011 | Pubmed ID: 21498416
Isl1 is required for multiple aspects of motor neuron development.
Molecular and cellular neurosciences Jul, 2011 | Pubmed ID: 21569850
Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.
Development (Cambridge, England) Oct, 2011 | Pubmed ID: 21937598
Early postmyocardial infarction survival in Murphy Roths Large mice is mediated by attenuated apoptosis and inflammation but depends on genetic background.
Experimental physiology Jan, 2012 | Pubmed ID: 21967898
Homotypic regulation of neuronal morphology and connectivity in the mouse retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2011 | Pubmed ID: 21976497
The heart endocardium is derived from vascular endothelial progenitors.
Development (Cambridge, England) Nov, 2011 | Pubmed ID: 21989917
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.
The Journal of clinical investigation Dec, 2011 | Pubmed ID: 22080862
Retinoic acid signaling regulates sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development.
Birth defects research. Part B, Developmental and reproductive toxicology Feb, 2012 | Pubmed ID: 22127979
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function.
Human molecular genetics May, 2012 | Pubmed ID: 22328084
Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc.
Developmental dynamics : an official publication of the American Association of Anatomists Apr, 2012 | Pubmed ID: 22354863
Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart.
Circulation research Mar, 2012 | Pubmed ID: 22427341
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos.
Development (Cambridge, England) May, 2012 | Pubmed ID: 22438573
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2012 | Pubmed ID: 22566629
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium.
Cell Aug, 2012 | Pubmed ID: 22863011
Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.
PloS one , 2012 | Pubmed ID: 23028455
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis.
Biology open Mar, 2012 | Pubmed ID: 23213408
Thymosin β4 is not required for embryonic viability or vascular development.
Circulation research Feb, 2013 | Pubmed ID: 23371905
To activate or not to activate: the existential dilemma of an enhancer.
Circulation research Mar, 2013 | Pubmed ID: 23538274
Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity.
Immunity Apr, 2013 | Pubmed ID: 23601687
Antagonism between retinoic acid and fibroblast growth factor signaling during limb development.
Cell reports May, 2013 | Pubmed ID: 23623500
Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT.
Journal of the American Society of Nephrology : JASN Jul, 2013 | Pubmed ID: 23641053
The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.
Developmental biology Aug, 2013 | Pubmed ID: 23648511
HCN4 dynamically marks the first heart field and conduction system precursors.
Circulation research Aug, 2013 | Pubmed ID: 23743334
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries.
Cell research Sep, 2013 | Pubmed ID: 23797856
Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor.
Nature Aug, 2013 | Pubmed ID: 23873040
Expression of Isl1 during mouse development.
Gene expression patterns : GEP Dec, 2013 | Pubmed ID: 23906961
Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model.
Human molecular genetics Mar, 2014 | Pubmed ID: 24108106
Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis.
BMC biology , 2013 | Pubmed ID: 24131868
Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2014 | Pubmed ID: 24351932
Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway.
Developmental biology Mar, 2014 | Pubmed ID: 24424161
Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.
PLoS genetics Feb, 2014 | Pubmed ID: 24586179
LIM homeodomain transcription factor Isl1 directs normal pyloric development via targeting Gata3.
BMC biology Mar, 2014 | Pubmed ID: 24674670
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