Sylvia M. Evans

Thymosin beta 4 is dispensable for murine cardiac development and function.

Development of the cardiac conduction system as delineated by minK-lacZ.

Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart development.

Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block.

T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.

Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification.

Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells.

Progenitor cells for cardiac repair.

Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis.

Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.

The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development.

The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway.

A myocardial lineage derives from Tbx18 epicardial cells.

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs.

Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.

Distinct origins and genetic programs of head muscle satellite cells.

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.

Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity.

Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.

Loss of enigma homolog protein results in dilated cardiomyopathy.

Distinction between two populations of islet-1-positive cells in hearts of different murine strains.

MicroRNAs in a cardiac loop: progenitor or myocyte?

Myocardial lineage development.

Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.

Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis.

Isl1 is required for multiple aspects of motor neuron development.

Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.

Early postmyocardial infarction survival in Murphy Roths Large mice is mediated by attenuated apoptosis and inflammation but depends on genetic background.

Homotypic regulation of neuronal morphology and connectivity in the mouse retina.

The heart endocardium is derived from vascular endothelial progenitors.

Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.

Retinoic acid signaling regulates sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development.

Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function.

Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc.

Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart.

Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos.

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.

Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium.

Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.

Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis.

Thymosin β4 is not required for embryonic viability or vascular development.

To activate or not to activate: the existential dilemma of an enhancer.

Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity.

Antagonism between retinoic acid and fibroblast growth factor signaling during limb development.

Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT.

The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.

HCN4 dynamically marks the first heart field and conduction system precursors.

Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries.

Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor.

Expression of Isl1 during mouse development.

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model.

Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis.

Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity.

Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway.

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

LIM homeodomain transcription factor Isl1 directs normal pyloric development via targeting Gata3.