MRC Protein Phosphorylation and Ubiquitylation Unit,
College of Life Sciences,
Centre for Gene Regulation and Expression,
MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences,
Centre for Gene Regulation and Expression, College of Life Sciences
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Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17360386
SUMO modification regulates MafB-driven macrophage differentiation by enabling Myb-dependent transcriptional repression.
Molecular and cellular biology Aug, 2007 | Pubmed ID: 17548468
In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy.
Molecular & cellular proteomics : MCP Jan, 2008 | Pubmed ID: 17938407
Ribosomal proteins are targets for the NEDD8 pathway.
EMBO reports Mar, 2008 | Pubmed ID: 18274552
NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts.
Journal of hepatology Apr, 2008 | Pubmed ID: 18279996
Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathway.
Protein science : a publication of the Protein Society Apr, 2008 | Pubmed ID: 18359863
Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity.
Cancer research Apr, 2008 | Pubmed ID: 18381449
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.
Nature cell biology May, 2008 | Pubmed ID: 18408734
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.
Nature May, 2008 | Pubmed ID: 18449195
Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo.
Genes & development Sep, 2008 | Pubmed ID: 18794353
FRET-based in vitro assays for the analysis of SUMO protease activities.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19107423
Characterization of SENP7, a SUMO-2/3-specific isopeptidase.
The Biochemical journal Jul, 2009 | Pubmed ID: 19392659
System-wide changes to SUMO modifications in response to heat shock.
Science signaling , 2009 | Pubmed ID: 19471022
An additional role for SUMO in ubiquitin-mediated proteolysis.
Nature reviews. Molecular cell biology Aug, 2009 | Pubmed ID: 19474794
Detection of protein SUMOylation in vivo.
Nature protocols , 2009 | Pubmed ID: 19730420
Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation.
The international journal of biochemistry & cell biology May, 2010 | Pubmed ID: 20080206
High-stringency tandem affinity purification of proteins conjugated to ubiquitin-like moieties.
Nature protocols May, 2010 | Pubmed ID: 20431533
Post-translational modification by SUMO.
Toxicology Dec, 2010 | Pubmed ID: 20674646
SUMOylation of the GTPase Rac1 is required for optimal cell migration.
Nature cell biology Nov, 2010 | Pubmed ID: 20935639
Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies.
Molecular biology of the cell Dec, 2010 | Pubmed ID: 20943951
Functional interactions between ubiquitin E2 enzymes and TRIM proteins.
The Biochemical journal Mar, 2011 | Pubmed ID: 21143188
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies.
Molecular biology of the cell Jan, 2011 | Pubmed ID: 21148299
Purification and identification of endogenous polySUMO conjugates.
EMBO reports Feb, 2011 | Pubmed ID: 21252943
Comparative proteomic analysis identifies a role for SUMO in protein quality control.
Science signaling , 2011 | Pubmed ID: 21693764
Absolute SILAC-compatible expression strain allows Sumo-2 copy number determination in clinical samples.
Journal of proteome research Oct, 2011 | Pubmed ID: 21830832
Mechanism of ubiquitylation by dimeric RING ligase RNF4.
Nature structural & molecular biology Sep, 2011 | Pubmed ID: 21857666
Stable-isotope labeling with amino acids in nematodes.
Nature methods , 2011 | Pubmed ID: 21874007
Detection and quantitation of SUMO chains by mass spectrometry.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22350890
SUMOylation of HNF4α regulates protein stability and hepatocyte function.
Journal of cell science Aug, 2012 | Pubmed ID: 22505616
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage.
Genes & development Jun, 2012 | Pubmed ID: 22661230
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis.
Nature Sep, 2012 | Pubmed ID: 22842904
Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites.
Nature methods Aug, 2012 | Pubmed ID: 22847107
The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.
The Biochemical journal Apr, 2013 | Pubmed ID: 23398456
Decoding the SUMO signal.
Biochemical Society transactions Apr, 2013 | Pubmed ID: 23514139
Ube2W conjugates ubiquitin to α-amino groups of protein N-termini.
The Biochemical journal Jul, 2013 | Pubmed ID: 23560854
Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation.
European journal of organic chemistry Nov, 2009 | Pubmed ID: 23606807
A role for paralog-specific sumoylation in histone deacetylase 1 stability.
Journal of molecular cell biology Dec, 2013 | Pubmed ID: 24068740
BC-box protein domain-related mechanism for VHL protein degradation.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2013 | Pubmed ID: 24145437
PML isoforms in response to arsenic: high resolution analysis of PML body structure and degradation characteristics.
Journal of cell science Nov, 2013 | Pubmed ID: 24190887
SUMO chain-induced dimerization activates RNF4.
Molecular cell Mar, 2014 | Pubmed ID: 24656128
E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin.
Cancer research Apr, 2014 | Pubmed ID: 24686174
Proteome-Wide Identification of SUMO2 Modification Sites.
Science signaling , 2014 | Pubmed ID: 24782567
Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.
Molecular oncology Apr, 2014 | Pubmed ID: 24816189
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