Environmental Health Science and Research Bureau,
Health Canada,
Environmental Health Science and Research Bureau, Health Canada
George R. Douglas has not added Biography.
If you are George R. Douglas and would like to personalize this page please email our Author Liaison for assistance.
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mutagenesis in cultured Big Blue rat mammary epithelial and fibroblast cells.
Environmental and molecular mutagenesis , 2002 | Pubmed ID: 11921195
Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue rat tongue epithelial cells and fibroblasts.
Mutation research Jan, 2003 | Pubmed ID: 12517416
Treatment and sampling protocols for transgenic mutation assays.
Environmental and molecular mutagenesis , 2003 | Pubmed ID: 12552586
In vivo transgenic mutation assays.
Mutation research Oct, 2003 | Pubmed ID: 14550498
Development and characterization of a stable epithelial cell line from Muta Mouse lung.
Environmental and molecular mutagenesis , 2003 | Pubmed ID: 14556224
Comprehensive comparison of six microarray technologies.
Nucleic acids research , 2004 | Pubmed ID: 15333675
Molecular insight into the effects of hypothyroidism on the developing cerebellum.
Biochemical and biophysical research communications May, 2005 | Pubmed ID: 15823568
Automation of cDNA microarray hybridization and washing yields improved data quality.
Journal of biochemical and biophysical methods Jul, 2005 | Pubmed ID: 16005076
A lacZ transgenic mouse assay for the detection of mutations in follicular granulosa cells.
Mutation research Oct, 2005 | Pubmed ID: 16039675
Detailed review of transgenic rodent mutation assays.
Mutation research Sep, 2005 | Pubmed ID: 16081315
Assessment of 3-nitrobenzanthrone reductase activity in mammalian tissues by normal-phase HPLC with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Sep, 2005 | Pubmed ID: 16095987
Meeting report: Validation of toxicogenomics-based test systems: ECVAM-ICCVAM/NICEATM considerations for regulatory use.
Environmental health perspectives Mar, 2006 | Pubmed ID: 16507466
Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo(a)pyrene, etoposide and okadaic acid.
Mutation research Jun, 2006 | Pubmed ID: 16516931
Detection of induced male germline mutation: correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays.
Mutation research Jun, 2006 | Pubmed ID: 16542687
Novel design and controls for focused DNA microarrays: applications in quality assurance/control and normalization for the Health Canada ToxArray.
BMC genomics , 2006 | Pubmed ID: 17052352
Hepatic gene expression changes in hypothyroid juvenile mice: characterization of a novel negative thyroid-responsive element.
Endocrinology Aug, 2007 | Pubmed ID: 17463053
Mainstream tobacco smoke causes paternal germ-line DNA mutation.
Cancer research Jun, 2007 | Pubmed ID: 17545587
Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells.
Environmental and molecular mutagenesis Jul, 2007 | Pubmed ID: 17584883
Analysis of gene expression in two human-derived cell lines exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field.
Proteomics Nov, 2007 | Pubmed ID: 17902192
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2008 | Pubmed ID: 18195365
Mutagenic and carcinogenic hazards of settled house dust. I: Polycyclic aromatic hydrocarbon content and excess lifetime cancer risk from preschool exposure.
Environmental science & technology Mar, 2008 | Pubmed ID: 18441830
Mutagenic and carcinogenic hazards of settled house dust. II: Salmonella mutagenicity.
Environmental science & technology Mar, 2008 | Pubmed ID: 18441831
Tissue-specific metabolic activation and mutagenicity of 3-nitrobenzanthrone in MutaMouse.
Environmental and molecular mutagenesis Oct, 2008 | Pubmed ID: 18613036
Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in MutaMouse and lung epithelial cells derived from MutaMouse.
Mutagenesis Nov, 2008 | Pubmed ID: 18635558
Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart.
Inhalation toxicology Jan, 2009 | Pubmed ID: 18925475
Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme.
Mutagenesis Jul, 2009 | Pubmed ID: 19535363
The genotoxicity of mainstream and sidestream marijuana and tobacco smoke condensates.
Chemical research in toxicology Aug, 2009 | Pubmed ID: 19947653
Induction of lacZ mutations in MutaMouse primary hepatocytes.
Environmental and molecular mutagenesis May, 2010 | Pubmed ID: 19953605
Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements.
Mutagenesis Nov, 2010 | Pubmed ID: 20724577
New and emerging technologies for genetic toxicity testing.
Environmental and molecular mutagenesis Apr, 2011 | Pubmed ID: 20740635
Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black.
Environmental and molecular mutagenesis May, 2011 | Pubmed ID: 20963790
Assessment of subclinical, toxicant-induced hepatic gene expression profiles after low-dose, short-term exposures in mice.
Regulatory toxicology and pharmacology : RTP Jun, 2011 | Pubmed ID: 21335049
Suitable top concentration for tests with mammalian cells: mouse lymphoma assay workgroup.
Mutation research Aug, 2011 | Pubmed ID: 21514400
Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse.
Environmental and molecular mutagenesis Dec, 2011 | Pubmed ID: 21976233
Harnessing genomics to identify environmental determinants of heritable disease.
Mutation research Aug, 2012 | Pubmed ID: 22935230
The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development.
Environmental and molecular mutagenesis Mar, 2013 | Pubmed ID: 23355186
No evidence for transgenerational genomic instability in the F1 or F2 descendants of Muta™Mouse males exposed to N-ethyl-N-nitrosourea.
Mutation research Jan-Feb, 2013 | Pubmed ID: 23499255
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유