Division of Allergy and Immunology,
Department of Pediatrics,
Division of Allergy and Immunology, Department of Pediatrics
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The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.
Nature medicine Feb, 2013 | Pubmed ID: 23334847
Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes.
The Journal of allergy and clinical immunology Jan, 2004 | Pubmed ID: 14699394
Eosinophilic gastrointestinal disorders (EGID).
The Journal of allergy and clinical immunology Jan, 2004 | Pubmed ID: 14713902
Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2004 | Pubmed ID: 14734765
Foxa2 regulates alveolarization and goblet cell hyperplasia.
Development (Cambridge, England) Feb, 2004 | Pubmed ID: 14757645
Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9).
Proceedings of the National Academy of Sciences of the United States of America Feb, 2004 | Pubmed ID: 14769916
Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma.
American journal of respiratory cell and molecular biology Sep, 2004 | Pubmed ID: 15087305
Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jul, 2004 | Pubmed ID: 15224281
T helper-2 immunity regulates bronchial hyperresponsiveness in eosinophil-associated gastrointestinal disease in mice.
Gastroenterology Jul, 2004 | Pubmed ID: 15236177
Eosinophilic esophagitis.
The New England journal of medicine Aug, 2004 | Pubmed ID: 15329438
VEGF obstructs the lungs.
Nature medicine Oct, 2004 | Pubmed ID: 15459700
Arginine in asthma and lung inflammation.
The Journal of nutrition Oct, 2004 | Pubmed ID: 15465795
Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2004 | Pubmed ID: 15585884
Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection.
European journal of immunology Jan, 2005 | Pubmed ID: 15593125
Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15647285
Expression and regulation of small proline-rich protein 2 in allergic inflammation.
American journal of respiratory cell and molecular biology May, 2005 | Pubmed ID: 15731505
Molecular mechanisms of anaphylaxis: lessons from studies with murine models.
The Journal of allergy and clinical immunology Mar, 2005 | Pubmed ID: 15753886
CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism.
Blood Jul, 2005 | Pubmed ID: 15802529
Analysis of the CCR3 promoter reveals a regulatory region in exon 1 that binds GATA-1.
BMC immunology , 2005 | Pubmed ID: 15807893
Suppressive effect of IL-4 on IL-13-induced genes in mouse lung.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2005 | Pubmed ID: 15814686
Anti-IL-5 and hypereosinophilic syndromes.
Clinical immunology (Orlando, Fla.) Apr, 2005 | Pubmed ID: 15870021
Eliminating eosinophilic esophagitis.
Clinical immunology (Orlando, Fla.) May, 2005 | Pubmed ID: 15885634
Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study.
Journal of pediatric gastroenterology and nutrition Jul, 2005 | Pubmed ID: 15990624
Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice.
Gastroenterology Sep, 2005 | Pubmed ID: 16143136
The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2005 | Pubmed ID: 16210640
Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity.
Journal of agricultural and food chemistry Nov, 2005 | Pubmed ID: 16277398
Eosinophilic esophagitis.
Current opinion in pediatrics Dec, 2005 | Pubmed ID: 16282772
The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.
Blood May, 2006 | Pubmed ID: 16418325
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.
The Journal of clinical investigation Feb, 2006 | Pubmed ID: 16453027
The arginine-arginase balance in asthma and lung inflammation.
European journal of pharmacology Mar, 2006 | Pubmed ID: 16458291
Eosinophil Function in Eosinophil-associated Gastrointestinal Disorders.
Current allergy and asthma reports Feb, 2006 | Pubmed ID: 16476198
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
The Journal of allergy and clinical immunology Mar, 2006 | Pubmed ID: 16522458
The eosinophil.
Annual review of immunology , 2006 | Pubmed ID: 16551246
Persistent effects induced by IL-13 in the lung.
American journal of respiratory cell and molecular biology Sep, 2006 | Pubmed ID: 16645178
Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.
Proceedings of the National Academy of Sciences of the United States of America May, 2006 | Pubmed ID: 16648267
ICAM-1-dependent pathways regulate colonic eosinophilic inflammation.
Journal of leukocyte biology Aug, 2006 | Pubmed ID: 16731772
Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report.
The Journal of allergy and clinical immunology Jun, 2006 | Pubmed ID: 16750989
The role of Th2 cytokines, chemokines and parasite products in eosinophil recruitment to the gastrointestinal mucosa during helminth infection.
European journal of immunology Jul, 2006 | Pubmed ID: 16783848
CD48 is an allergen and IL-3-induced activation molecule on eosinophils.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2006 | Pubmed ID: 16785501
Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses.
The Journal of allergy and clinical immunology Jul, 2006 | Pubmed ID: 16815139
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility.
The Journal of allergy and clinical immunology Jul, 2006 | Pubmed ID: 16815164
Experimental gastrointestinal allergy enhances pulmonary responses to specific and unrelated allergens.
The Journal of allergy and clinical immunology Aug, 2006 | Pubmed ID: 16890767
Quantity and distribution of eosinophils in the gastrointestinal tract of children.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society May-Jun, 2006 | Pubmed ID: 16944979
Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17003120
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2006 | Pubmed ID: 17015747
Potential of blood eosinophils, eosinophil-derived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Nov, 2006 | Pubmed ID: 17059896
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17060636
Eosinophilic esophagitis: pathogenesis, genetics, and therapy.
The Journal of allergy and clinical immunology Nov, 2006 | Pubmed ID: 17088129
A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis.
Gastroenterology Nov, 2006 | Pubmed ID: 17101314
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling.
The American journal of pathology Dec, 2006 | Pubmed ID: 17148674
Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis.
The Journal of allergy and clinical immunology Dec, 2006 | Pubmed ID: 17157662
Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung.
Experimental lung research Nov-Dec, 2006 | Pubmed ID: 17169855
Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice.
Journal of leukocyte biology Apr, 2007 | Pubmed ID: 17194734
Pediatric patients with eosinophilic esophagitis: an 8-year follow-up.
The Journal of allergy and clinical immunology Mar, 2007 | Pubmed ID: 17258309
CD48 is critically involved in allergic eosinophilic airway inflammation.
American journal of respiratory and critical care medicine May, 2007 | Pubmed ID: 17290046
Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I.
The Journal of allergy and clinical immunology Feb, 2007 | Pubmed ID: 17291856
Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2007 | Pubmed ID: 17371978
Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation.
The Journal of clinical investigation May, 2007 | Pubmed ID: 17415415
Eosinophils in the new millennium.
The Journal of allergy and clinical immunology Jun, 2007 | Pubmed ID: 17451795
Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung.
American journal of physiology. Lung cellular and molecular physiology Aug, 2007 | Pubmed ID: 17545488
Interplay of adaptive th2 immunity with eotaxin-3/c-C chemokine receptor 3 in eosinophilic esophagitis.
Journal of pediatric gastroenterology and nutrition Jul, 2007 | Pubmed ID: 17592361
Gastrointestinal eosinophilia.
Immunology and allergy clinics of North America Aug, 2007 | Pubmed ID: 17868858
Summary of the First International Gastrointestinal Eosinophil Research Symposium.
Journal of pediatric gastroenterology and nutrition Sep, 2007 | Pubmed ID: 17873754
An eosinophil hypothesis for functional dyspepsia.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Oct, 2007 | Pubmed ID: 17916543
Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment.
Gastroenterology Oct, 2007 | Pubmed ID: 17919504
Basic pathogenesis of eosinophilic esophagitis.
Gastrointestinal endoscopy clinics of North America Jan, 2008 | Pubmed ID: 18061107
IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids.
The Journal of allergy and clinical immunology Dec, 2007 | Pubmed ID: 18073124
Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia.
Gastroenterology Jan, 2008 | Pubmed ID: 18166354
A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils.
Blood Jun, 2008 | Pubmed ID: 18316626
Treatment of patients with the hypereosinophilic syndrome with mepolizumab.
The New England journal of medicine Mar, 2008 | Pubmed ID: 18344568
IL-4R alpha expression by bone marrow-derived cells is necessary and sufficient for host protection against acute schistosomiasis.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2008 | Pubmed ID: 18354220
Surfactant protein D alters allergic lung responses in mice and human subjects.
The Journal of allergy and clinical immunology May, 2008 | Pubmed ID: 18355911
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.
The Journal of experimental medicine Apr, 2008 | Pubmed ID: 18378796
Eosinophils: biological properties and role in health and disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology May, 2008 | Pubmed ID: 18384431
Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels.
The Journal of allergy and clinical immunology Jun, 2008 | Pubmed ID: 18410960
2007 E. Mead Johnson award: scientific pursuit of the allergy problem.
Pediatric research Jul, 2008 | Pubmed ID: 18414146
Clinical, pathologic, and molecular characterization of familial eosinophilic esophagitis compared with sporadic cases.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jun, 2008 | Pubmed ID: 18434257
Origin, regulation and physiological function of intestinal oeosinophils.
Best practice & research. Clinical gastroenterology , 2008 | Pubmed ID: 18492563
Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein.
Journal of leukocyte biology Sep, 2008 | Pubmed ID: 18519743
FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome.
Blood Sep, 2008 | Pubmed ID: 18539901
Allergy and eosinophil-associated gastrointestinal disorders (EGID).
Current opinion in immunology Dec, 2008 | Pubmed ID: 18721876
Mitochondrial missile defense.
Nature medicine Sep, 2008 | Pubmed ID: 18776879
Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2008 | Pubmed ID: 18981162
Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea.
The Journal of allergy and clinical immunology Jan, 2009 | Pubmed ID: 18996576
Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis.
The Journal of allergy and clinical immunology Dec, 2008 | Pubmed ID: 19084112
Chemotactic factors associated with eosinophilic gastrointestinal diseases.
Immunology and allergy clinics of North America Feb, 2009 | Pubmed ID: 19141349
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade.
International immunology Feb, 2009 | Pubmed ID: 19147836
Dissociation between symptoms and histological severity in pediatric eosinophilic esophagitis.
Journal of pediatric gastroenterology and nutrition Feb, 2009 | Pubmed ID: 19179876
Resistin-like molecule alpha decreases glucose tolerance during intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2009 | Pubmed ID: 19201890
Biology of the eosinophil.
Advances in immunology , 2009 | Pubmed ID: 19231593
Molecular diagnostics and treatment of patients with the hypereosinophilic syndrome.
Clinical advances in hematology & oncology : H&O Jan, 2009 | Pubmed ID: 19274040
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2009 | Pubmed ID: 19342679
Eosinophilic esophagitis: concepts, controversies, and evidence.
Current gastroenterology reports Jun, 2009 | Pubmed ID: 19463222
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice.
BMC immunology , 2009 | Pubmed ID: 19486531
Murine model of hypereosinophilic syndromes/chronic eosinophilic leukemia.
International archives of allergy and immunology , 2009 | Pubmed ID: 19494514
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Nature Jul, 2009 | Pubmed ID: 19525930
Biology and treatment of eosinophilic esophagitis.
Gastroenterology Oct, 2009 | Pubmed ID: 19596009
Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner.
Blood Sep, 2009 | Pubmed ID: 19641187
Hypersensitivity and allergy: from mice to men.
Current opinion in immunology Dec, 2009 | Pubmed ID: 19879743
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
The Journal of allergy and clinical immunology Dec, 2009 | Pubmed ID: 19910029
Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection.
The Journal of experimental medicine Dec, 2009 | Pubmed ID: 19995957
Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma.
European journal of human genetics : EJHG Jun, 2010 | Pubmed ID: 20087405
Persistent rotavirus vaccine shedding in a new case of severe combined immunodeficiency: A reason to screen.
The Journal of allergy and clinical immunology Jan, 2010 | Pubmed ID: 20109754
Health-related quality of life across pediatric chronic conditions.
The Journal of pediatrics Apr, 2010 | Pubmed ID: 20117793
Importance of cytokines in murine allergic airway disease and human asthma.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2010 | Pubmed ID: 20130218
Key advances in mechanisms of asthma, allergy, and immunology in 2009.
The Journal of allergy and clinical immunology Feb, 2010 | Pubmed ID: 20159240
Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1.
Psychoneuroendocrinology Sep, 2010 | Pubmed ID: 20171785
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2010 | Pubmed ID: 20208004
Common variants at 5q22 associate with pediatric eosinophilic esophagitis.
Nature genetics Apr, 2010 | Pubmed ID: 20208534
Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51.
The Journal of allergy and clinical immunology Apr, 2010 | Pubmed ID: 20371398
Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice.
Gastroenterology Jul, 2010 | Pubmed ID: 20381491
Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract.
The Journal of allergy and clinical immunology Jul, 2010 | Pubmed ID: 20392477
Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis.
Gastroenterology Aug, 2010 | Pubmed ID: 20398663
Indoor insect allergens are potent inducers of experimental eosinophilic esophagitis in mice.
Journal of leukocyte biology Aug, 2010 | Pubmed ID: 20413729
Hypereosinophilic syndromes and new therapeutic approaches including anti-IL-5.
Expert review of clinical immunology Nov, 2005 | Pubmed ID: 20477604
Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2010 | Pubmed ID: 20483789
IL-5 pathway inhibition in the treatment of asthma and Churg-Strauss syndrome.
The Journal of allergy and clinical immunology Jun, 2010 | Pubmed ID: 20513522
Involvement of mast cells in eosinophilic esophagitis.
The Journal of allergy and clinical immunology Jul, 2010 | Pubmed ID: 20538331
IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2010 | Pubmed ID: 20543112
The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis.
Respiratory research , 2010 | Pubmed ID: 20576117
Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999.
The Journal of allergy and clinical immunology Jul, 2010 | Pubmed ID: 20620567
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis.
The Journal of allergy and clinical immunology Jul, 2010 | Pubmed ID: 20620568
Refining the definition of hypereosinophilic syndrome.
The Journal of allergy and clinical immunology Jul, 2010 | Pubmed ID: 20639008
Innate sensing of nickel.
Nature immunology Sep, 2010 | Pubmed ID: 20720584
Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies.
Mitochondrion Jan, 2011 | Pubmed ID: 20817046
IL-13Rα2 has a protective role in a mouse model of cutaneous inflammation.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2010 | Pubmed ID: 20971924
TGF-β1: Mediator of a feedback loop in eosinophilic esophagitis--or should we really say mastocytic esophagitis?
The Journal of allergy and clinical immunology Dec, 2010 | Pubmed ID: 21134572
The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice.
Peptides Apr, 2011 | Pubmed ID: 21167892
A striking local esophageal cytokine expression profile in eosinophilic esophagitis.
The Journal of allergy and clinical immunology Jan, 2011 | Pubmed ID: 21211656
Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21303908
Epigenetic regulation of the IL-13-induced human eotaxin-3 gene by CREB-binding protein-mediated histone 3 acetylation.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21325281
Advances in mechanisms of asthma, allergy, and immunology in 2010.
The Journal of allergy and clinical immunology Mar, 2011 | Pubmed ID: 21377038
Differences in candidate gene association between European ancestry and African American asthmatic children.
PloS one , 2011 | Pubmed ID: 21387019
Eosinophilic esophagitis: updated consensus recommendations for children and adults.
The Journal of allergy and clinical immunology Jul, 2011 | Pubmed ID: 21477849
Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11.
Journal of immunology (Baltimore, Md. : 1950) May, 2011 | Pubmed ID: 21498668
Psychological Functioning of Children and Adolescents With Eosinophil-Associated Gastrointestinal Disorders.
Children's health care : journal of the Association for the Care of Children's Health Oct, 2010 | Pubmed ID: 21532963
Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies.
The Journal of allergy and clinical immunology Jul, 2011 | Pubmed ID: 21570716
Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2.
International archives of allergy and immunology , 2011 | Pubmed ID: 21576984
Long-term outcomes in pediatric-onset esophageal eosinophilia.
The Journal of allergy and clinical immunology Jul, 2011 | Pubmed ID: 21636117
MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2011 | Pubmed ID: 21849676
IL-13 receptor α1 differentially regulates aeroallergen-induced lung responses.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2011 | Pubmed ID: 21957151
Eosinophilic esophagitis: rapidly advancing insights.
Annual review of medicine , 2012 | Pubmed ID: 22034864
Treatment adherence in pediatric eosinophilic gastrointestinal disorders.
Journal of pediatric psychology Jun, 2012 | Pubmed ID: 22080457
Development of a validated patient-reported symptom metric for pediatric eosinophilic esophagitis: qualitative methods.
BMC gastroenterology , 2011 | Pubmed ID: 22099448
The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophilia.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2012 | Pubmed ID: 22190185
Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial.
The Journal of allergy and clinical immunology Feb, 2012 | Pubmed ID: 22206777
Resistin-like molecule-α regulates IL-13-induced chemokine production but not allergen-induced airway responses.
American journal of respiratory cell and molecular biology May, 2012 | Pubmed ID: 22246861
Advances in mechanisms of asthma, allergy, and immunology in 2011.
The Journal of allergy and clinical immunology Feb, 2012 | Pubmed ID: 22284930
MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers.
The Journal of allergy and clinical immunology Apr, 2012 | Pubmed ID: 22391115
Behavioral functioning and treatment adherence in pediatric eosinophilic gastrointestinal disorders.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Aug, 2012 | Pubmed ID: 22435992
Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis.
The Journal of allergy and clinical immunology Jun, 2012 | Pubmed ID: 22541246
The Greater Cincinnati Pediatric Clinic Repository: A Novel Framework for Childhood Asthma and Allergy Research.
Pediatric allergy, immunology, and pulmonology Jun, 2012 | Pubmed ID: 22768387
Behavioral feeding problems and parenting stress in eosinophilic gastrointestinal disorders in children.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Dec, 2012 | Pubmed ID: 22882380
Novel targeted therapies for eosinophilic disorders.
The Journal of allergy and clinical immunology Sep, 2012 | Pubmed ID: 22935585
Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD).
The Journal of allergy and clinical immunology Sep, 2012 | Pubmed ID: 22935587
Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis.
The Journal of allergy and clinical immunology Sep, 2012 | Pubmed ID: 22935588
Development of the Pediatric Quality of Life Inventory™ Eosinophilic Esophagitis module items: qualitative methods.
BMC gastroenterology , 2012 | Pubmed ID: 23009120
Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes.
The Journal of allergy and clinical immunology Feb, 2013 | Pubmed ID: 23040887
Reply: To PMID 22541246.
The Journal of allergy and clinical immunology Jan, 2013 | Pubmed ID: 23127828
Commentary on "Markers of Antigen Presentation And Activation On Eosinophils And T-Cells in the Esophageal Tissue of Patients With Eosinophilic Esophagitis"
Journal of pediatric gastroenterology and nutrition Nov, 2012 | Pubmed ID: 23132165
The Child Health Research Centers: twenty-one years of promoting the development of pediatrician scientists from 1990-2011.
The Journal of pediatrics Dec, 2012 | Pubmed ID: 23171484
ICON: Eosinophil Disorders.
The World Allergy Organization journal Dec, 2012 | Pubmed ID: 23282419
MiR-223 deficiency increases eosinophil progenitor proliferation.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2013 | Pubmed ID: 23325891
Targeting eosinophils in allergy, inflammation and beyond.
Nature reviews. Drug discovery Feb, 2013 | Pubmed ID: 23334207
Advances in mechanisms of allergy and clinical immunology in 2012.
The Journal of allergy and clinical immunology Mar, 2013 | Pubmed ID: 23352632
PedsQL eosinophilic esophagitis module: feasibility, reliability, and validity.
Journal of pediatric gastroenterology and nutrition Jul, 2013 | Pubmed ID: 23478422
Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth.
PloS one , 2013 | Pubmed ID: 23533623
Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23536294
Emerging concepts of dietary therapy for pediatric and adult eosinophilic esophagitis.
Expert review of clinical immunology Apr, 2013 | Pubmed ID: 23557262
High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders.
The Journal of allergy and clinical immunology Aug, 2013 | Pubmed ID: 23608731
Current concepts on the pathogenesis of the hypereosinophilic syndrome/chronic eosinophilic leukemia.
Translational oncogenomics , 2006 | Pubmed ID: 23662039
Expanding the paradigm of eosinophilic esophagitis: mast cells and IL-9.
The Journal of allergy and clinical immunology Jun, 2013 | Pubmed ID: 23726533
Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases.
The Journal of allergy and clinical immunology Jul, 2013 | Pubmed ID: 23735656
Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.
Human genomics , 2013 | Pubmed ID: 23829686
Molecular diagnosis of eosinophilic esophagitis by gene expression profiling.
Gastroenterology Dec, 2013 | Pubmed ID: 23978633
IL-33 markedly activates murine eosinophils by an NF-κB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2013 | Pubmed ID: 24043894
Eosinophilic asthma: insights into the effects of reducing IL-5 receptor-positive cell levels.
The Journal of allergy and clinical immunology Nov, 2013 | Pubmed ID: 24094543
Paired immunoglobulin-like receptor A is an intrinsic, self-limiting suppressor of IL-5-induced eosinophil development.
Nature immunology Jan, 2014 | Pubmed ID: 24212998
Correlation of increased PARP14 and CCL26 expression in biopsies from children with eosinophilic esophagitis.
The Journal of allergy and clinical immunology Feb, 2014 | Pubmed ID: 24238647
Demethylation of the human eotaxin-3 gene promoter leads to the elevated expression of eotaxin-3.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2014 | Pubmed ID: 24323578
Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes.
Journal of pediatric gastroenterology and nutrition May, 2014 | Pubmed ID: 24345843
Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities.
The Journal of allergy and clinical immunology May, 2014 | Pubmed ID: 24472624
The management of eosinophilic esophagitis.
The journal of allergy and clinical immunology. In practice Jul-Aug, 2013 | Pubmed ID: 24565538
Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis.
Journal of immunology (Baltimore, Md. : 1950) May, 2014 | Pubmed ID: 24696234
Efficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitis.
Gastroenterology Aug, 2014 | Pubmed ID: 24768678
Eosinophils and cancer.
Cancer immunology research Jan, 2014 | Pubmed ID: 24778159
Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease.
Inflammatory bowel diseases Jun, 2014 | Pubmed ID: 24788216
Carbonic anhydrase IV is expressed on IL-5-activated murine eosinophils.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2014 | Pubmed ID: 24808371
Genetic and epigenetic underpinnings of eosinophilic esophagitis.
Gastroenterology clinics of North America Jun, 2014 | Pubmed ID: 24813515
Murine models of eosinophilic leukemia: a model of FIP1L1-PDGFRα initiated chronic eosinophilic leukemia/systemic mastocytosis.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24986627
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.
Nature genetics Aug, 2014 | Pubmed ID: 25017104
Roles and regulation of gastrointestinal eosinophils in immunity and disease.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2014 | Pubmed ID: 25049430
Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis.
The Journal of allergy and clinical immunology Sep, 2014 | Pubmed ID: 25226850
IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2014 | Pubmed ID: 25230753
Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome.
The Journal of allergy and clinical immunology Nov, 2014 | Pubmed ID: 25234644
Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis.
The Journal of allergy and clinical immunology Nov, 2014 | Pubmed ID: 25258143
Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation.
The Journal of allergy and clinical immunology Jan, 2015 | Pubmed ID: 25441638
Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis.
Frontiers in genetics , 2014 | Pubmed ID: 25477900
Making it big in allergy.
The Journal of allergy and clinical immunology Jan, 2015 | Pubmed ID: 25567041
Resistin-like Molecule Alpha in Allergen-induced Pulmonary Vascular Remodeling.
American journal of respiratory cell and molecular biology Jan, 2015 | Pubmed ID: 25569618
1Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University,
2Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine,
3Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University
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