Hanry Yu

Polyphosphoester microspheres for sustained release of biologically active nerve growth factor.

Microcapsules with improved mechanical stability for hepatocyte culture.

Antisense telomerase induced cell growth inhibition, cell cycle arrest and telomerase activity down-regulation in gastric and colon cancer cells.

Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits.

Kinectin anchors the translation elongation factor-1 delta to the endoplasmic reticulum.

Cloning of rat telomerase catalytic subunit functional domains, reconstitution of telomerase activity and enzymatic profile of pig and chicken tissues.

Use of ultrathin shell microcapsules of hepatocytes in bioartificial liver-assist device.

Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance.

Strategies for the cryopreservation of microencapsulated cells.

Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation.

Evaluation of collagen and methylated collagen as gene carriers.

Distribution and functions of kinectin isoforms.

Quantitative measurement of collagen methylation by capillary electrophoresis.

Optimization of 3-D hepatocyte culture by controlling the physical and chemical properties of the extra-cellular matrices.

Application of a polyelectrolyte complex coacervation method to improve seeding efficiency of bone marrow stromal cells in a 3D culture system.

TGF-beta1 regulation in hepatocyte-NIH3T3 co-culture is important for the enhanced hepatocyte function in 3D microenvironment.

Scalable encapsulation of hepatocytes by electrostatic spraying.

A configurable three-dimensional microenvironment in a microfluidic channel for primary hepatocyte culture.

Characterization of amphoteric multilayered thin films by means of zeta potential measurements.

Encapsulating live cells with water-soluble chitosan in physiological conditions.

Factors influencing stem cell differentiation into the hepatic lineage in vitro.

Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells.

An engineered microenvironment for multidimensional microscopy of live cells.

Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture.

Detection of telomerase activity in gastric lavage fluid: a novel method to detect gastric cancer.

3D hepatocyte monolayer on hybrid RGD/galactose substratum.

Kinectin-dependent assembly of translation elongation factor-1 complex on endoplasmic reticulum regulates protein synthesis.

Improved hepatocyte excretory function by immediate presentation of polarity cues.

[Encapsulating hepatocytes with chitosan in physiological conditions].

A novel 3D mammalian cell perfusion-culture system in microfluidic channels.

Characterization of flow direction in microchannels and zebrafish blood vessels by scanning fluorescence correlation spectroscopy.

Vitreous cryopreservation of cell-biomaterial constructs involving encapsulated hepatocytes.

Transient inter-cellular polymeric linker.

Perfusion culture improves the maintenance of cultured liver tissue slices.

Identification and characterization of a novel prespheroid 3-dimensional hepatocyte monolayer on galactosylated substratum.

A practical guide to microfluidic perfusion culture of adherent mammalian cells.

Multifunctional fluorescence correlation microscope for intracellular and microfluidic measurements.

Novel intra-tissue perfusion system for culturing thick liver tissue.

Synthetic sandwich culture of 3D hepatocyte monolayer.

In vivo activity of ABT-869, a multi-target kinase inhibitor, against acute myeloid leukemia with wild-type FLT3 receptor.

Integrating sensitive quantification of hepatic metabolic functions by capillary electrophoresis with laser-induced fluorescence detection.

A gel-free 3D microfluidic cell culture system.

Dendrimer hydrazides as multivalent transient inter-cellular linkers.

Microfabricated silicon nitride membranes for hepatocyte sandwich culture.

Spreading of an anchorage-dependent cell on a selectively ligand-coated substrate mediated by receptor-ligand binding.

Nonlinear optical microscopy: use of second harmonic generation and two-photon microscopy for automated quantitative liver fibrosis studies.

Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.

Stem cells in microfluidics.

The controlled presentation of TGF-beta1 to hepatocytes in a 3D-microfluidic cell culture system.

Line scan fluorescence correlation spectroscopy for three-dimensional microfluidic flow velocity measurements.

The use of vitrification to preserve primary rat hepatocyte monolayer on collagen-coated poly(ethylene-terephthalate) surfaces for a hybrid liver support system.

A microfluidic 3D hepatocyte chip for drug toxicity testing.

Laminar-flow immediate-overlay hepatocyte sandwich perfusion system for drug hepatotoxicity testing.

Fibro-C-Index: comprehensive, morphology-based quantification of liver fibrosis using second harmonic generation and two-photon microscopy.

Towards a human-on-chip: culturing multiple cell types on a chip with compartmentalized microenvironments.

Engineering a scaffold-free 3D tumor model for in vitro drug penetration studies.

The steady states and dynamics of urokinase-mediated plasmin activation.

Cell culture on MEMS platforms: a review.

Cell-delivery therapeutics for liver regeneration.

Rapid construction of mechanically- confined multi- cellular structures using dendrimeric intercellular linker.

Preparation of three-dimensional interconnected macroporous cellulosic hydrogels for soft tissue engineering.

A robust high-throughput sandwich cell-based drug screening platform.

Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella.

Toward surface quantification of liver fibrosis progression.

Pulse-modulated second harmonic imaging microscope quantitatively demonstrates marked increase of collagen in tumor after chemotherapy.

Purpose-driven biomaterials research in liver-tissue engineering.

Current development of bioreactors for extracorporeal bioartificial liver (Review).

PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapy.

Galactosylated cellulosic sponge for multi-well drug safety testing.

Exploitation of physical and chemical constraints for three-dimensional microtissue construction in microfluidics.

Steady states and dynamics of urokinase-mediated plasmin activation in silico and in vitro.

Spatially organized in vitro models instruct asymmetric stem cell differentiation.

Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis.

Influence of cell culture configuration on the post-cryopreservation viability of primary rat hepatocytes.

Assessment of liver steatosis and fibrosis in rats using integrated coherent anti-Stokes Raman scattering and multiphoton imaging technique.

Fish and Chips: a microfluidic perfusion platform for monitoring zebrafish development.

Tethered spheroids as an in vitro hepatocyte model for drug safety screening.

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin.

Automated scoring of liver fibrosis through combined features from different collagen groups.

Hepatitis C virus network based classification of hepatocellular cirrhosis and carcinoma.

FUSE: a profit maximization approach for functional summarization of biological networks.

HGF regulates the activation of TGF-β1 in rat hepatocytes and hepatic stellate cells.

Hepatocyte function within a stacked double sandwich culture plate cylindrical bioreactor for bioartificial liver system.

Development of a modified vitrification strategy suitable for subsequent scale-up for hepatocyte preservation.

Plasmin triggers a switch-like decrease in thrombospondin-dependent activation of TGF-β1.

Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza.

Mechanical compaction directly modulates the dynamics of bile canaliculi formation.

Direct detection of collagenous proteins by fluorescently labeled collagen mimetic peptides.

Hepatic stellate cell-targeted delivery of hepatocyte growth factor transgene via bile duct infusion enhances its expression at fibrotic foci to regress dimethylnitrosamine-induced liver fibrosis.

Spatiotemporal quantification of cell dynamics in the lung following influenza virus infection.

Scalable cell alignment on optical media substrates.

In vitro testicular toxicity models: opportunities for advancement via biomedical engineering techniques.

A cellular pathway involved in Clara cell to alveolar type II cell differentiation after severe lung injury.

Scalable alignment of three-dimensional cellular constructs in a microfluidic chip.

Correlation of MR elastography with morphometric quantification of liver fibrosis (Fibro-C-Index) in chronic hepatitis B.

Label-free virus identification and characterization using electrochemical impedance spectroscopy.

qFibrosis: a fully-quantitative innovative method incorporating histological features to facilitate accurate fibrosis scoring in animal model and chronic hepatitis B patients.

Experimenting liver fibrosis diagnostic by two photon excitation microscopy and Bag-of-Features image classification.

Scalable spheroid model of human hepatocytes for hepatitis C infection and replication.

Reassignment of scattered emission photons in multifocal multiphoton microscopy.

The self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.

Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia.

On-chip controlled surfactant-DNA coil-globule transition by rapid solvent exchange using hydrodynamic flow focusing.

In vivo label-free quantification of liver microcirculation using dual-modality microscopy.

HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening.

Differential remodeling of extracellular matrices by breast cancer initiating cells.

Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation.

A method for human teratogen detection by geometrically confined cell differentiation and migration.

Quantification of liver fibrosis via second harmonic imaging of the Glisson's capsule from liver surface.

Multiple C2 domains transmembrane protein 1 is expressed in CNS neurons and possibly regulates cellular vesicle retrieval and oxidative stress.

Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model.

Second harmonic generation microscopy is a novel technique for differential diagnosis of breast fibroepithelial lesions.

Corrigendum: A method for human teratogen detection by geometrically confined cell differentiation and migration.

Cost-effective differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules.

Constrained spheroids for prolonged hepatocyte culture.

Extracellular matrix scaffolding guides lumen elongation by inducing anisotropic intercellular mechanical tension.

Functionally Enhanced Human Stem Cell Derived Hepatocytes in Galactosylated Cellulosic Sponges for Hepatotoxicity Testing.

Fluorescent probes for nanoscopy: four categories and multiple possibilities.

Kinectin-dependent ER transport supports the focal complex maturation required for chemotaxis in shallow gradients.

Aggregation and protein corona formation on gold nanoparticles affect viability and liver functions of primary rat hepatocytes.

Heralding a new paradigm in 3D tumor modeling.

Butein and Its Role in Chronic Diseases.

A vertical-flow bioreactor array compacts hepatocytes for enhanced polarity and functions.

Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity.

Actomyosin contractility drives bile regurgitation as an early response during obstructive cholestasis.

25-Hydroxyvitamin D induces osteogenic differentiation of human mesenchymal stem cells.

3D Culture as a Clinically Relevant Model for Personalized Medicine.

Human Stem Cell-Derived Endothelial-Hepatic Platform for Efficacy Testing of Vascular-Protective Metabolites from Nutraceuticals.

A pump-free microfluidic 3D perfusion platform for the efficient differentiation of human hepatocyte-like cells.

Development of a classification model for non-alcoholic steatohepatitis (NASH) using confocal Raman micro-spectroscopy.

Mechanosensing in liver regeneration.

In Vitro Micropatterned Human Pluripotent Stem Cell Test (µP-hPST) for Morphometric-Based Teratogen Screening.

A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing.

Computational analysis reveals the coupling between bistability and the sign of a feedback loop in a TGF-β1 activation model.

Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer.

TGFβ1-mediated suppression of cytochrome P450(CYP) induction responses in rat hepatocyte-fibroblast co-cultures.

Directed Differentiation of Adult Liver Derived Mesenchymal Like Stem Cells into Functional Hepatocytes.

A 3D Microfluidic Model to Recapitulate Cancer Cell Migration and Invasion.

Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3σ.

Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel.

PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Constrained spheroids/organoids in perfusion culture.

Author Correction: PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Metabolic Remodeling during Liver Regeneration.

Deep learning enables automated scoring of liver fibrosis stages.

Cleavable cellulosic sponge for functional hepatic cell culture and retrieval.

Self-assembling amyloid-like peptides as exogenous second harmonic probes for bioimaging applications.

Hepatic spheroids used as an in vitro model to study malaria relapse.

Studying nucleic envelope and plasma membrane mechanics of eukaryotic cells using confocal reflectance interferometric microscopy.

Sequential drug delivery for liver diseases.

IL-13-driven alterations in hepatic cholesterol handling contributes to hypercholesterolemia in a rat model of minimal change disease.

Decellularized liver as a translucent ex vivo model for vascular embolization evaluation.

Tethered primary hepatocyte spheroids on polystyrene multi-well plates for high-throughput drug safety testing.

Biomimetic niches reveal the minimal cues to trigger apical lumen formation in single hepatocytes.

Functional Stem Cell Sorting via Integrative Droplet Synchronization.

Bile canaliculi contract autonomously by releasing calcium into hepatocytes via mechanosensitive calcium channel.

Hydrogel-based colorectal cancer organoid co-culture models.

Substrate Stiffness Modulates the Maturation of Human Pluripotent Stem-Cell-Derived Hepatocytes.

Three-Dimensional Macroporous Sponge for the Culture of Hepatocellular Carcinoma Patient-Derived Xenograft Organoids.