Peter A. Calabresi

Unmasking of autoimmune hepatitis in a patient with MS following interferon beta therapy.

Considerations in the treatment of relapsing-remitting multiple sclerosis.

Chemokine receptor expression on MBP-reactive T cells: CXCR6 is a marker of IFNgamma-producing effector cells.

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS.

Kinetics of CCR7 expression differ between primary activation and effector memory states of T(H)1 and T(H)2 cells.

Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.

Diagnosis and management of multiple sclerosis.

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases.

2004 Pathogenesis of rare neuroimmunologic disorders, Hyatt Regency Inner Harbor, Baltimore, MD, August 19th 2004-August 20th 2004.

Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale.

Bystander modulation of chemokine receptor expression on peripheral blood T lymphocytes mediated by glatiramer therapy.

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis.

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease.

Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis.

Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis.

Natalizumab plus interferon beta-1a for relapsing multiple sclerosis.

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor.

Potassium channels Kv1.3 and Kv1.5 are expressed on blood-derived dendritic cells in the central nervous system.

Memory lineage relationships in HTLV-1-specific CD8+ cytotoxic T cells.

Pulsed magnetization transfer imaging with body coil transmission at 3 Tesla: feasibility and application.

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.

Agar-gelatin for embedding tissues prior to paraffin processing.

High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord.

Dendritic cells are abundant in non-lesional gray matter in multiple sclerosis.

Health-related quality of life in multiple sclerosis: effects of natalizumab.

Investigating glatiramer acetate for relapsing-remitting multiple sclerosis at the double dose--is more better?

Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis.

Characterization of the functional properties of the voltage-gated potassium channel Kv1.3 in human CD4+ T lymphocytes.

Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification.

Cleavage of myelin associated glycoprotein by matrix metalloproteinases.

Future research directions in multiple sclerosis therapies.

The diagnosis of MS: white spots and red flags.

Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial.

Interleukin-17 in transverse myelitis and multiple sclerosis.

High b-value q-space diffusion-weighted MRI of the human cervical spinal cord in vivo: feasibility and application to multiple sclerosis.

Reduction of disease activity and disability with high-dose cyclophosphamide in patients with aggressive multiple sclerosis.

Retinal imaging by laser polarimetry and optical coherence tomography evidence of axonal degeneration in multiple sclerosis.

A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis.

Reproducibility of optical coherence tomography in multiple sclerosis.

FLT3 inhibitors for the treatment of autoimmune disease.

Optical coherence tomography: a window into the mechanisms of multiple sclerosis.

Axonal protective effects of the myelin-associated glycoprotein.

Natalizumab: bound to rebound?

Diffusion tensor magnetic resonance imaging of Wallerian degeneration in rat spinal cord after dorsal root axotomy.

Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord.

Signal transduction inhibition of APCs diminishes th17 and Th1 responses in experimental autoimmune encephalomyelitis.

The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL.

Imaging outcomes for neuroprotection and repair in multiple sclerosis trials.

Damage to the optic radiation in multiple sclerosis is associated with retinal injury and visual disability.

Complex geometric models of diffusion and relaxation in healthy and damaged white matter.

A topology-preserving approach to the segmentation of brain images with multiple sclerosis lesions.

Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.

Macular volume determined by optical coherence tomography as a measure of neuronal loss in multiple sclerosis.

Reproducibility of tract-specific magnetization transfer and diffusion tensor imaging in the cervical spinal cord at 3 tesla.

Automated vs. conventional tractography in multiple sclerosis: variability and correlation with disability.

Promising treatments of tomorrow for multiple sclerosis.

Multiple sclerosis: can retinal imaging accurately detect optic neuritis?

Natalizumab plus interferon beta-1a reduces lesion formation in relapsing multiple sclerosis.

Diffusion tensor imaging of the optic tracts in multiple sclerosis: association with retinal thinning and visual disability.

Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers.

q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy.

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

Retinal pathology in multiple sclerosis: insight into the mechanisms of neuronal pathology.

Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis.

Reproducibility of high-resolution optical coherence tomography in multiple sclerosis.

FLT-3 expression and function on microglia in multiple sclerosis.

Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis.

Cutting edge: The transcription factor Kruppel-like factor 4 regulates the differentiation of Th17 cells independently of RORγt.

Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography.

Optical coherence tomography (OCT): imaging the visual pathway as a model for neurodegeneration.

Quantitative measures detect sensory and motor impairments in multiple sclerosis.

Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients.

One eye or two: a comparison of binocular and monocular low-contrast acuity testing in multiple sclerosis.

The expanding spectrum of aetiologies causing retinal microcystic macular change.

Probing mouse brain microstructure using oscillating gradient diffusion MRI.

Retinal ganglion cell layer volumetric assessment by spectral-domain optical coherence tomography in multiple sclerosis: application of a high-precision manual estimation technique.

In vivo and ex vivo diffusion tensor imaging of cuprizone-induced demyelination in the mouse corpus callosum.

The impact of utilizing different optical coherence tomography devices for clinical purposes and in multiple sclerosis trials.

Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness.

NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination.

Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis.

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial.

Functional blockade of the voltage-gated potassium channel Kv1.3 mediates reversion of T effector to central memory lymphocytes through SMAD3/p21cip1 signaling.

Inflammation in multiple sclerosis--sorting out the gray matter.

Decreased microglial activation in MS patients treated with glatiramer acetate.

PEGylation of interferon-β-1a: a promising strategy in multiple sclerosis.

Detection of clinical and subclinical retinal abnormalities in neurosarcoidosis with optical coherence tomography.

New and emerging disease modifying therapies for multiple sclerosis.

Visual pathway axonal loss in benign multiple sclerosis: a longitudinal study.

Ganglion cell loss in relation to visual disability in multiple sclerosis.

In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques.

Low-contrast acuity measures visual improvement in phase 3 trial of natalizumab in relapsing MS.

Kv1.3 deletion biases T cells toward an immunoregulatory phenotype and renders mice resistant to autoimmune encephalomyelitis.

Revisiting brain atrophy and its relationship to disability in multiple sclerosis.

Expression of CCR7 and CD45RA in CD4+ and CD8+ subsets in cerebrospinal fluid of 134 patients with inflammatory and non-inflammatory neurological diseases.

Can PET imaging tell us what's the matter with the gray matter in multiple sclerosis?

Multifocal visual evoked potentials are influenced by variable contrast stimulation in MS.

Development of protein biomarkers in cerebrospinal fluid for secondary progressive multiple sclerosis using selected reaction monitoring mass spectrometry (SRM-MS).

Tract-specific quantitative MRI better correlates with disability than conventional MRI in multiple sclerosis.

Multiparametric MRI correlates of sensorimotor function in the spinal cord in multiple sclerosis.

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

Comparison of point estimates and average thicknesses of retinal layers measured using manual optical coherence tomography segmentation for quantification of retinal neurodegeneration in multiple sclerosis.

Objective characterization of the relative afferent pupillary defect in MS.

Varicella-zoster virus encephalitis and vasculopathy in a patient treated with fingolimod.

Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study.

PML-IRIS in a patient treated with brentuximab.

Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.

Axial 3D gradient-echo imaging for improved multiple sclerosis lesion detection in the cervical spinal cord at 3T.

Active MS is associated with accelerated retinal ganglion cell/inner plexiform layer thinning.

In vivo demonstration of homonymous hemimacular loss of retinal ganglion cells due to a thalamic lesion using optical coherence tomography.

Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis.

Spinal cord quantitative MRI discriminates between disability levels in multiple sclerosis.

Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.

Clay-shoveler's fracture during indoor rock climbing.

Quantitative MRI demonstrates abnormality of the fornix and cingulum in multiple sclerosis.

In vivo identification of morphologic retinal abnormalities in neuromyelitis optica.

Interferon beta use and disability prevention in relapsing-remitting multiple sclerosis.

Anti-interleukin-2 receptor alpha for multiple sclerosis?

Impaired toll-like receptor 8 signaling in multiple sclerosis.

Optic nerve head component responses of the multifocal electroretinogram in MS.

Optical coherence tomography in x-linked adrenoleukodystrophy.

KLF4 modulates expression of IL-6 in dendritic cells via both promoter activation and epigenetic modification.

Retinal layer segmentation of macular OCT images using boundary classification.

Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis.

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein.

Accelerated axon loss in MOG35-55 experimental autoimmune encephalomyelitis (EAE) in myelin-associated glycoprotein-deficient (MAGKO) mice.

Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells.

Varicella-zoster virus encephalitis and vasculopathy in a patient treated with fingolimod.

Baseline retinal nerve fiber layer thickness and macular volume quantified by OCT in the North American phase 3 fingolimod trial for relapsing-remitting multiple sclerosis.

Emerging injectable therapies for multiple sclerosis.

OASIS is Automated Statistical Inference for Segmentation, with applications to multiple sclerosis lesion segmentation in MRI.

Voxel-Wise Displacement as Independent Features in Classification of Multiple Sclerosis.

1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization.

Reconstruction of the human cerebral cortex robust to white matter lesions: method and validation.

DEFORMABLE REGISTRATION OF MACULAR OCT USING A-MODE SCAN SIMILARITY.

Daclizumab-induced adverse events in multiple organ systems in multiple sclerosis.

Author response.

Spinal cord normalization in multiple sclerosis.

FTY720 impairs CD8 T-cell function independently of the sphingosine-1-phosphate pathway.

Monocular and binocular low-contrast visual acuity and optical coherence tomography in pediatric multiple sclerosis.

Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial.

Multiple-object geometric deformable model for segmentation of macular OCT.

A comparison of supervised machine learning algorithms and feature vectors for MS lesion segmentation using multimodal structural MRI.

Photoreceptor layer thinning in idiopathic Parkinson's disease.

Retinal architecture and mfERG: Optic nerve head component response characteristics in MS.

Pegylated interferon β-1a for relapsing-remitting multiple sclerosis (ADVANCE): a randomised, phase 3, double-blind study.

The impact of dynamic balance measures on walking performance in multiple sclerosis.

A selective thyroid hormone β receptor agonist enhances human and rodent oligodendrocyte differentiation.

Defining the clinical course of multiple sclerosis: The 2013 revisions.

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics.

Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis.

Reply: photoreceptor layer thinning is not specific for Parkinson's disease.

Analysis of macular OCT images using deformable registration.

Single-use autoinjector for peginterferon-β1a treatment of relapsing-remitting multiple sclerosis: safety, tolerability and patient evaluation data from the Phase IIIb ATTAIN study.

Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: yes.

Health effects of lesion localization in multiple sclerosis: spatial registration and confounding adjustment.

Statistical normalization techniques for magnetic resonance imaging.

Complex antibody profiling to predict clinical outcome in childhood ADS.

Retinal damage and vision loss in African American multiple sclerosis patients.

Peginterferon beta-1a in multiple sclerosis: 2-year results from ADVANCE.

Effect of peginterferon beta-1a on MRI measures and achieving no evidence of disease activity: results from a randomized controlled trial in relapsing-remitting multiple sclerosis.

Thalamic lesions in multiple sclerosis by 7T MRI: Clinical implications and relationship to cortical pathology.

Relationships between quantitative spinal cord MRI and retinal layers in multiple sclerosis.

Automatic segmentation of microcystic macular edema in OCT.

1,25-Dihydroxyvitamin D3 impairs the differentiation of effector memory T cells in vitro in multiple sclerosis patients and healthy controls.

Quantitative sensory and motor measures detect change overtime and correlate with walking speed in individuals with multiple sclerosis.

Targeting repulsive guidance molecule A to promote regeneration and neuroprotection in multiple sclerosis.

Longitudinal relationships among posturography and gait measures in multiple sclerosis.

Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis.

Pathogenic aquaporin-4 reactive T cells are sufficient to induce mouse model of neuromyelitis optica.

Longitudinal graph-based segmentation of macular OCT using fundus alignment.

Segmentation of microcystic macular edema in Cirrus OCT scans with an exploratory longitudinal study.

Longitudinally extensive optic neuritis as an MRI biomarker distinguishes neuromyelitis optica from multiple sclerosis.

Transfer of myelin-reactive th17 cells impairs endogenous remyelination in the central nervous system of cuprizone-fed mice.

Magnetic susceptibility contrast variations in multiple sclerosis lesions.

Corrigendum to "Statistical normalization techniques for magnetic resonance imaging" [NeuroImage: Clinical 6 (2014) 9-19].

Applying an Open-Source Segmentation Algorithm to Different OCT Devices in Multiple Sclerosis Patients and Healthy Controls: Implications for Clinical Trials.

Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3-Independent T Cells with Suppressive Properties.

Optical coherence tomography reflects brain atrophy in multiple sclerosis: A four-year study.

Association of Cortical Lesion Burden on 7-T Magnetic Resonance Imaging With Cognition and Disability in Multiple Sclerosis.

Relation of quantitative visual and neurologic outcomes to fatigue in multiple sclerosis.

Differentiating neuromyelitis optica from other causes of longitudinally extensive transverse myelitis on spinal magnetic resonance imaging.

Outer retinal changes following acute optic neuritis.

Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination.

Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis.

Metabolomics in multiple sclerosis.