School of Pharmacy
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GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1.
Scientific reports , 2012 | Pubmed ID: 23019516
Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2013 | Pubmed ID: 23682122
Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases.
Neurobiology of disease Oct, 2013 | Pubmed ID: 23747310
Inhibition of LRRK2 kinase activity stimulates macroautophagy.
Biochimica et biophysica acta Dec, 2013 | Pubmed ID: 23916833
Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation.
Biochemical and biophysical research communications Nov, 2013 | Pubmed ID: 24211199
Rare variants in LRRK1 and Parkinson's disease.
Neurogenetics Mar, 2014 | Pubmed ID: 24241507
Computational analysis of the LRRK2 interactome.
PeerJ , 2015 | Pubmed ID: 25737818
Cellular processes associated with LRRK2 function and dysfunction.
The FEBS journal Aug, 2015 | Pubmed ID: 25899482
Genetic and phenotypic characterization of complex hereditary spastic paraplegia.
Brain : a journal of neurology 07, 2016 | Pubmed ID: 27217339
mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1.
Scientific reports 10, 2016 | Pubmed ID: 27731364
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences.
Briefings in bioinformatics Mar, 2018 | Pubmed ID: 27881428
Weighted Protein Interaction Network Analysis of Frontotemporal Dementia.
Journal of proteome research 02, 2017 | Pubmed ID: 28004582
The LRRK2-macroautophagy axis and its relevance to Parkinson's disease.
Biochemical Society transactions 02, 2017 | Pubmed ID: 28202669
LRRK2 and Autophagy.
Advances in neurobiology , 2017 | Pubmed ID: 28353280
The LRRK2 signalling system.
Cell and tissue research Jul, 2018 | Pubmed ID: 29308544
Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.
Proteomics May, 2018 | Pubmed ID: 29513927
mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.
Bioscience reports Apr, 2018 | Pubmed ID: 29563162
Tau Mutations Serve as a Novel Risk Factor for Cancer.
Cancer research Jul, 2018 | Pubmed ID: 29794074
Stratification of candidate genes for Parkinson's disease using weighted protein-protein interaction network analysis.
BMC genomics Jun, 2018 | Pubmed ID: 29898659
Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology.
Brain research Jul, 2018 | Pubmed ID: 30055128
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