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Department of Nuclear Medicine and Radiobiology
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Prion protein aggresomes are poly(A)+ ribonucleoprotein complexes that induce a PKR-mediated deficient cell stress response.
Biochimica et biophysica acta Mar, 2008 | Pubmed ID: 18023289
Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells.
BMC cell biology Oct, 2008 | Pubmed ID: 18937858
A large ribonucleoprotein particle induced by cytoplasmic PrP shares striking similarities with the chromatoid body, an RNA granule predicted to function in posttranscriptional gene regulation.
Biochimica et biophysica acta Feb, 2009 | Pubmed ID: 19014979
Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization.
Molecular neurodegeneration Jan, 2013 | Pubmed ID: 23339399
ChAcNLS, a Novel Modification to Antibody-Conjugates Permitting Target Cell-Specific Endosomal Escape, Localization to the Nucleus, and Enhanced Total Intracellular Accumulation.
Molecular pharmaceutics Jun, 2016 | Pubmed ID: 27112376
Development of a Novel Covalent Folate-Albumin-Photosensitizer Conjugate.
Photochemistry and photobiology 07, 2016 | Pubmed ID: 27221219
BODIPY-17α-ethynylestradiol conjugates: Synthesis, fluorescence properties and receptor binding affinities.
Bioorganic & medicinal chemistry letters Feb, 2017 | Pubmed ID: 28049591
Targeting IL-5Rα with antibody-conjugates reveals a strategy for imaging and therapy for invasive bladder cancer.
Oncoimmunology , 2017 | Pubmed ID: 29123949
Université de Sherbrooke
Simon Beaudoin1,
Michel Paquette1,
Laurent Fafard-Couture1,
Mylene A. Tremblay1,
Roger Lecomte1,2,3,
Brigitte Guérin1,2,3,
Jeffrey V. Leyton1,2,3
1Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke,
2Sherbrooke Molecular Imaging Center (CIMS), Université de Sherbrooke,
3, Sherbrooke Institute of Pharmacology
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