Confocal Microscopy for Intracellular Accumulation Evaluation
4:49
Radiolabeled AC Construction and Cellular Fractionation for the Evaluation of 64Cu Intracellular Delivery Efficiency
8:23
PET Imaging Evaluation of Tumor Targeting
9:22
Results: Evaluation of Intracellular Accumulation of Antibody Conjugates
11:30
Conclusion
필기록
The overall goal of these procedures is to evaluate the specificity and effectiveness of antibody conjugates for accumulating inside target cells and tumors during the initial development stages so that they can ultimately be used in the clinic. T
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Viral-derived peptides coupled to antibody-conjugates (ACs) is an approach gaining momentum due to the potential of delivering molecular payloads with increased tumor cell accumulation. Utilizing common methods to evaluate peptide conjugation, AC and payload intracellular accumulation, and tumor targeting, this protocol helps researchers during the key initial development phases.