Ulf Dittmer

Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication.

Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.

Modification of one epitope-flanking amino acid allows for the induction of friend retrovirus-specific CD8+ T cells by Adenovirus-based immunization.

Interleukin 21 augments the hepatitis B virus-specific CD8+ T-cell response in vitro in patients coinfected with HIV-1.

CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells.

Overcoming drug-resistant herpes simplex virus (HSV) infection by a humanized antibody.

Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loads.

Interleukin-encoding adenoviral vectors as genetic adjuvant for vaccination against retroviral infection.

The phenotype and activation status of regulatory T cells during Friend retrovirus infection.

CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice.

Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.

Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection.

Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.

Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice.

Friend retrovirus drives cytotoxic effectors through Toll-like receptor 3.

Prevention of herpes simplex virus induced stromal keratitis by a glycoprotein B-specific monoclonal antibody.

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.

Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia.

Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection.

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses.

Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms.

CD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor Activity.

No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts.

Circulating HIV-Specific Interleukin-21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions.

Inhibition of catecholamine degradation ameliorates while chemical sympathectomy aggravates the severity of acute Friend retrovirus infection in mice.

Reduced Frequencies and Activation of Regulatory T Cells After the Treatment of HIV-1-Infected Individuals with the CCR5 Antagonist Maraviroc Are Associated with a Reduction in Viral Loads Rather Than a Direct Effect of the Drug on Regulatory T Cells.

Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection.

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo.

The V1 region of gp120 is preferentially selected during SIV/HIV transmission and is indispensable for envelope function and virus infection.

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.

CD169 macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection.

Different antiviral effects of IFNα and IFNβ in an HBV mouse model.

Pre-exposure prophylaxis failure with tenofovir disoproxil.

Filariae-Retrovirus Co-infection in Mice is Associated with Suppressed Virus-Specific IgG Immune Response and Higher Viral Loads.

Natural killer T cells contribute to the control of acute retroviral infection.

Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.

Interference of retroviral envelope with vaccine-induced CD8 T cell responses is relieved by co-administration of cytokine-encoding vectors.

Immunodominance of Adenovirus-Derived CD8 T Cell Epitopes Interferes with the Induction of Transgene-Specific Immunity in Adenovirus-Based Immunization.

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.

Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8 T cell responses during acute Friend retrovirus infection.

Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses.

Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection.

Antibody-based immunotherapy of aciclovir resistant ocular herpes simplex virus infections.

Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis.

Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotype.

An advanced BLT-humanized mouse model for extended HIV-1 cure studies.

Impact of low-level BK polyomavirus viremia on intermediate-term renal allograft function.

Expression Pattern of Individual IFNA Subtypes in Chronic HIV Infection.

Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells.

Regulatory T cells in retroviral infections.

Imaging of cytotoxic antiviral immunity while considering the 3R principle of animal research.

Interferon α subtypes in HIV infection.

Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8 T Cell Responses During Chronic Retroviral Infection.

Recent advances in the discovery and development of TLR ligands as novel therapeutics for chronic HBV and HIV infections.

Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodies.

The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10 Regulatory T Cells During Acute Retroviral Infection.

Impact of immune suppressive agents on the BK-Polyomavirus non coding control region.

Corrigendum to "Antibody-based immunotherapy of acyclovir resistant ocular herpes simplex virus infection" [Virology 512 (2017) 194-200].

Friend retrovirus infection induces the development of memory-like natural killer cells.

PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice.

Induction of herpes simplex virus type 1 cell-to-cell spread inhibiting antibodies by a calcium phosphate nanoparticle-based vaccine.

Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance.

Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells.

The detection of BKPyV genotypes II and IV after renal transplantation as a simple tool for risk assessment for PyVAN and transplant outcome already at early stages of BKPyV reactivation.

Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral Persistence.

The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8 T Cells During an Acute Retroviral Infection.

Plasmacytoid dendritic cells respond to Epstein-Barr virus infection with a distinct type I interferon subtype profile.

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.