Department of Pathology,
Microbiology and Immunology,
Department of Pathology, Microbiology and Immunology
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Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.
Journal of virology May, 2002 | Pubmed ID: 11932428
Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication.
Journal of virology Jun, 2002 | Pubmed ID: 11991995
Disassembly of human immunodeficiency virus type 1 cores in vitro reveals association of Nef with the subviral ribonucleoprotein complex.
Journal of virology Apr, 2003 | Pubmed ID: 12634398
Nef does not affect the efficiency of human immunodeficiency virus type 1 fusion with target cells.
Journal of virology Oct, 2003 | Pubmed ID: 12970449
Small-molecule inhibition of human immunodeficiency virus type 1 replication by specific targeting of the final step of virion maturation.
Journal of virology Jan, 2004 | Pubmed ID: 14694123
Bifunctional anti-human immunodeficiency virus type 1 small molecules with two novel mechanisms of action.
Antimicrobial agents and chemotherapy Feb, 2004 | Pubmed ID: 14742233
Assembly properties of the human immunodeficiency virus type 1 CA protein.
Journal of virology Mar, 2004 | Pubmed ID: 14963157
Coupling of human immunodeficiency virus type 1 fusion to virion maturation: a novel role of the gp41 cytoplasmic tail.
Journal of virology Apr, 2004 | Pubmed ID: 15016865
Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.
Journal of virology Jun, 2004 | Pubmed ID: 15163722
The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid.
Retrovirology , 2004 | Pubmed ID: 15225375
Structural requirements for recognition of the human immunodeficiency virus type 1 core during host restriction in owl monkey cells.
Journal of virology Jan, 2005 | Pubmed ID: 15613315
Betulinic acid derivatives as HIV-1 antivirals.
Trends in molecular medicine Jan, 2005 | Pubmed ID: 15649820
Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.
Journal of virology Sep, 2005 | Pubmed ID: 16140737
Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles.
The Journal of biological chemistry Dec, 2005 | Pubmed ID: 16251182
Maturation of the viral core enhances the fusion of HIV-1 particles with primary human T cells and monocyte-derived macrophages.
Virology Mar, 2006 | Pubmed ID: 16375941
A mutation in the human immunodeficiency virus type 1 Gag protein destabilizes the interaction of the envelope protein subunits gp120 and gp41.
Journal of virology Mar, 2006 | Pubmed ID: 16474147
Evidence for a functional link between uncoating of the human immunodeficiency virus type 1 core and nuclear import of the viral preintegration complex.
Journal of virology Apr, 2006 | Pubmed ID: 16571788
Saturation of TRIM5 alpha-mediated restriction of HIV-1 infection depends on the stability of the incoming viral capsid.
Virology Jul, 2006 | Pubmed ID: 16624363
Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels.
The Journal of investigative dermatology Feb, 2007 | Pubmed ID: 16917492
Human immunodeficiency virus type 1 resistance to the small molecule maturation inhibitor 3-O-(3',3'-dimethylsuccinyl)-betulinic acid is conferred by a variety of single amino acid substitutions at the CA-SP1 cleavage site in Gag.
Journal of virology Dec, 2006 | Pubmed ID: 17035324
Selective restriction of Nef-defective human immunodeficiency virus type 1 by a proteasome-dependent mechanism.
Journal of virology Feb, 2007 | Pubmed ID: 17108041
A mutation in alpha helix 3 of CA renders human immunodeficiency virus type 1 cyclosporin A resistant and dependent: rescue by a second-site substitution in a distal region of CA.
Journal of virology Apr, 2007 | Pubmed ID: 17267487
Maturation-dependent human immunodeficiency virus type 1 particle fusion requires a carboxyl-terminal region of the gp41 cytoplasmic tail.
Journal of virology Sep, 2007 | Pubmed ID: 17609279
Analysis of human cell heterokaryons demonstrates that target cell restriction of cyclosporine-resistant human immunodeficiency virus type 1 mutants is genetically dominant.
Journal of virology Nov, 2007 | Pubmed ID: 17715216
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.
Journal of virology Nov, 2007 | Pubmed ID: 17804494
Nef enhances HIV-1 infectivity via association with the virus assembly complex.
Virology Apr, 2008 | Pubmed ID: 18191978
Proteasomal degradation of TRIM5alpha during retrovirus restriction.
PLoS pathogens May, 2008 | Pubmed ID: 18497858
Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication.
Journal of virology Dec, 2008 | Pubmed ID: 18799573
Cyclophilin A-dependent restriction of human immunodeficiency virus type 1 capsid mutants for infection of nondividing cells.
Journal of virology Dec, 2008 | Pubmed ID: 18829762
Cell-free assays for HIV-1 uncoating.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19020817
Viral and cellular factors that regulate HIV-1 uncoating.
Current opinion in HIV and AIDS May, 2006 | Pubmed ID: 19372808
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.
Cell Nov, 2009 | Pubmed ID: 19914170
Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization.
The Journal of biological chemistry Apr, 2010 | Pubmed ID: 20147291
TRIM5alpha disrupts the structure of assembled HIV-1 capsid complexes in vitro.
Journal of virology Jul, 2010 | Pubmed ID: 20410272
Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.
Journal of virology Jan, 2011 | Pubmed ID: 20962083
Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding.
Journal of molecular biology Feb, 2011 | Pubmed ID: 21146540
Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.
PLoS pathogens Mar, 2011 | Pubmed ID: 21455494
免疫学: TRIM5 没有双重职责。
Nature Apr, 2011 | Pubmed ID: 21512569
Maturation-induced cloaking of neutralization epitopes on HIV-1 particles.
PLoS pathogens Sep, 2011 | Pubmed ID: 21931551
HIV Nuclear Entry: Clearing the Fog.
Viruses May, 2010 | Pubmed ID: 21994675
RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating.
Journal of virology Feb, 2012 | Pubmed ID: 22114335
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