Beijing Institute of Ophthalmology,
Beijing Tongren Eye Center,
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center
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Molecular diagnosis of putative Stargardt disease by capture next generation sequencing.
PloS one , 2014 | Pubmed ID: 24763286
A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family.
Scientific reports Nov, 2014 | Pubmed ID: 25374051
The Association between Maternal Reproductive Age and Progression of Refractive Error in Urban Students in Beijing.
PloS one , 2015 | Pubmed ID: 26421841
Molecular genetic analysis and phenotypic characteristics of a consanguineous family with glycogen storage disease type Ia.
Molecular medicine reports Oct, 2016 | Pubmed ID: 27511118
ATP1A3 mutation as a candidate cause of autosomal dominant cone-rod dystrophy.
Human genetics Nov, 2020 | Pubmed ID: 32440726
Emerging roles of non-coding RNAs in retinal diseases: A review.
Clinical & experimental ophthalmology 11, 2020 | Pubmed ID: 32519377
Bioenergetic Crosstalk between Mesenchymal Stem Cells and various Ocular Cells through the intercellular trafficking of Mitochondria.
Theranostics , 2020 | Pubmed ID: 32641991
COCO enhances the efficiency of photoreceptor precursor differentiation in early human embryonic stem cell-derived retinal organoids.
Stem cell research & therapy 08, 2020 | Pubmed ID: 32831148
Generation of Nonhuman Primate Model of Cone Dysfunction through AAV-Mediated Ablation.
Molecular therapy. Methods & clinical development Sep, 2020 | Pubmed ID: 32953936
Towards stem cell-based neuronal regeneration for glaucoma.
Progress in brain research , 2020 | Pubmed ID: 32988476
The road to restore vision with photoreceptor regeneration.
Experimental eye research 01, 2021 | Pubmed ID: 33010290
Generation of three human iPSC lines from a retinitis pigmentosa family with SLC7A14 mutation.
Stem cell research 12, 2020 | Pubmed ID: 33207307
Abundant Neural circRNA Cdr1as Is Not Indispensable for Retina Maintenance.
Frontiers in cell and developmental biology , 2020 | Pubmed ID: 33240875
Human embryonic stem cell-derived organoid retinoblastoma reveals a cancerous origin.
Proceedings of the National Academy of Sciences of the United States of America 12, 2020 | Pubmed ID: 33318192
Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish.
Histology and histopathology Jan, 2021 | Pubmed ID: 33491763
Eyes on coronavirus.
Stem cell research 03, 2021 | Pubmed ID: 33535156
Variant Profiling of a Large Cohort of 138 Chinese Families With Autosomal Dominant Retinitis Pigmentosa.
Frontiers in cell and developmental biology , 2020 | Pubmed ID: 33598457
Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China.
Annals of translational medicine Feb, 2021 | Pubmed ID: 33708872
Genotype-Phenotype Analysis and Mutation Spectrum in a Cohort of Chinese Patients With Congenital Nystagmus.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 33732697
Circular RNAs in the Central Nervous System.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 33816552
Modeling retinitis pigmentosa through patient-derived retinal organoids.
STAR protocols 06, 2021 | Pubmed ID: 33899019
Modeling human retinoblastoma using embryonic stem cell-derived retinal organoids.
STAR protocols 06, 2021 | Pubmed ID: 33899024
Investigation of Macular Choroidal Thickness and Blood Flow Change by Optical Coherence Tomography Angiography After Posterior Scleral Reinforcement.
Frontiers in medicine , 2021 | Pubmed ID: 34017847
Conversion of mouse embryonic fibroblasts into neural crest cells and functional corneal endothelia by defined small molecules.
Science advances 06, 2021 | Pubmed ID: 34088673
Consanguinity-based analysis of exome sequencing yields likely genetic causes in patients with inherited retinal dystrophy.
Orphanet journal of rare diseases 06, 2021 | Pubmed ID: 34130719
Genetic Screening Revealed Latent Keratoconus in Asymptomatic Individuals.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34136477
Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis.
Annals of the rheumatic diseases Apr, 2021 | Pubmed ID: 34161253
Genotype Profile of Global EYS-Associated Inherited Retinal Dystrophy and Clinical Findings in a Large Chinese Cohort.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34178978
Whole-Exome Sequencing in a Cohort of High Myopia Patients in Northwest China.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34222226
Stem Cell-Based Regeneration and Restoration for Retinal Ganglion Cell: Recent Advancements and Current Challenges.
Biomolecules 07, 2021 | Pubmed ID: 34356611
The association of myopia progression with the morphological changes of optic disc and β-peripapillary atrophy in primary school students.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Feb, 2022 | Pubmed ID: 34357418
miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle.
EMBO reports 09, 2021 | Pubmed ID: 34358402
Retinal Degeneration Caused by Ago2 Disruption.
Investigative ophthalmology & visual science 09, 2021 | Pubmed ID: 34529004
Mitochondrial Mutations in Ethambutol-Induced Optic Neuropathy.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34676220
Retinal organoids as models for development and diseases.
Cell regeneration (London, England) Nov, 2021 | Pubmed ID: 34719743
Clinical Features and Natural History in a Cohort of Chinese Patients with RPE65-Associated Inherited Retinal Dystrophy.
Journal of clinical medicine Nov, 2021 | Pubmed ID: 34830511
Implantable collamer lens versus small incision lenticule extraction for high myopia correction: A systematic review and meta-analysis.
BMC ophthalmology Dec, 2021 | Pubmed ID: 34961514
The Impact of Study-at-Home During the COVID-19 Pandemic on Myopia Progression in Chinese Children.
Frontiers in public health , 2021 | Pubmed ID: 35071149
Requirements for human-induced pluripotent stem cells.
Cell proliferation Apr, 2022 | Pubmed ID: 35083805
Association Between Color Vision Deficiency and Myopia in Chinese Children Over a Five-Year Period.
Investigative ophthalmology & visual science 02, 2022 | Pubmed ID: 35103751
miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 02, 2022 | Pubmed ID: 35105806
New loci for refractive errors and ocular biometric parameters in young Chinese Han adults.
Science China. Life sciences Mar, 2022 | Pubmed ID: 35301706
CLEC3B is a novel causative gene for macular-retinal dystrophy.
Genetics in medicine : official journal of the American College of Medical Genetics Jun, 2022 | Pubmed ID: 35331648
MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation.
iScience Apr, 2022 | Pubmed ID: 35359806
Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction.
Science advances 04, 2022 | Pubmed ID: 35394837
Functional microglia derived from human pluripotent stem cells empower retinal organ.
Science China. Life sciences Jun, 2022 | Pubmed ID: 35451725
Identification of a New Mutation p.P88L in Connexin 50 Associated with Dominant Congenital Cataract.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35531093
Therapeutic Effects of Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells on a Murine Model of Acute Type-2-Dominated Airway Inflammation.
Stem cell reviews and reports May, 2022 | Pubmed ID: 35622293
Phenotype-Based Genetic Analysis Reveals Missing Heritability of ABCA4-Related Retinopathy: Deep Intronic Variants and Copy Number Variations.
Investigative ophthalmology & visual science 06, 2022 | Pubmed ID: 35657619
'RetinoGenetics': a comprehensive mutation database for genes related to inherited retinal degeneration.
Database : the journal of biological databases and curation , 2014 | Pubmed ID: 24939193
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
American journal of human genetics Aug, 2022 | Pubmed ID: 35931049
Global spectrum of mutation in inherited retinal dystrophies: Prompt message for development of base editing therapy.
Frontiers in aging neuroscience , 2022 | Pubmed ID: 36034145
Effects and Prognosis of Cataract Surgery in Patients with Retinitis Pigmentosa.
Ophthalmology and therapy Dec, 2022 | Pubmed ID: 36057888
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance.
Nature metabolism Oct, 2022 | Pubmed ID: 36203054
A saturated map of common genetic variants associated with human height.
Nature Oct, 2022 | Pubmed ID: 36224396
Author Correction: Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance.
Nature metabolism Oct, 2022 | Pubmed ID: 36241712
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Genome biology Dec, 2022 | Pubmed ID: 36575460
Mechanosensitive channel Piezo1 is an essential regulator in cell cycle progression of optic nerve head astrocytes.
Glia May, 2023 | Pubmed ID: 36598105
Second hit impels oncogenesis of retinoblastoma in patient-induced pluripotent stem cell-derived retinal organoids: direct evidence for Knudson's theory.
PNAS nexus Sep, 2022 | Pubmed ID: 36714839
SLAMF7/STAT6 Pathway Inhibits Innate Immune Response in Late-Stage Human Keratitis: A Comparative Transcriptome Analysis.
Microorganisms Feb, 2023 | Pubmed ID: 36838330
Time-Course Transcriptomic Analysis Reveals the Crucial Roles of PANoptosis in Fungal Keratitis.
Investigative ophthalmology & visual science Mar, 2023 | Pubmed ID: 36867131
Prevalence and Characteristics of Myopia in Adult Rhesus Macaques in Southwest China.
Translational vision science & technology Mar, 2023 | Pubmed ID: 36947048
Mutational investigation of 17 causative genes in a cohort of 113 families with nonsyndromic early-onset high myopia in northwestern China.
Molecular genetics and genomics : MGG May, 2023 | Pubmed ID: 36964802
Immunomodulatory properties of mesenchymal stem cells: A potential therapeutic strategy for allergic rhinitis.
Allergy Jun, 2023 | Pubmed ID: 36975714
IMI-Management and Investigation of High Myopia in Infants and Young Children.
Investigative ophthalmology & visual science May, 2023 | Pubmed ID: 37126360
Generation of the induced pluripotent stem cell line SFMUi001-A from a patient with usher syndrome type 2 caused by biallelic variants in the USH2A gene.
Stem cell research Jun, 2023 | Pubmed ID: 37126974
A rational consideration of the genomic instability of human-induced pluripotent stem cells for clinical applications.
Science China. Life sciences Sep, 2023 | Pubmed ID: 37296348
Retinal organoid and gene editing for basic and translational research.
Vision research Sep, 2023 | Pubmed ID: 37307693
Six-month repeated irradiation of 650 nm low-level red light reduces the risk of myopia in children: a randomized controlled trial.
International ophthalmology Oct, 2023 | Pubmed ID: 37318667
Evaluation of Limbal Stem Cells in Patients With Type 2 Diabetes: An In Vivo Confocal Microscopy Study.
Cornea Jan, 2024 | Pubmed ID: 37399570
Implementing a digital comprehensive myopia prevention and control strategy for children and adolescents in China: a cost-effectiveness analysis.
The Lancet regional health. Western Pacific Sep, 2023 | Pubmed ID: 37520278
REG1A protects retinal photoreceptors from blue light damage.
Annals of the New York Academy of Sciences Sep, 2023 | Pubmed ID: 37531162
Deep phenotyping of 11,880 highlanders reveals novel adaptive traits in native Tibetans.
iScience Sep, 2023 | Pubmed ID: 37680474
Clinical Features of Fundus Tessellation and Its Relationship with Myopia: A Systematic Review and Meta-analysis.
Ophthalmology and therapy Dec, 2023 | Pubmed ID: 37733224
Comprehensive Genetic Analysis Unraveled the Missing Heritability and a Founder Variant of BEST1 in a Chinese Cohort With Autosomal Recessive Bestrophinopathy.
Investigative ophthalmology & visual science Sep, 2023 | Pubmed ID: 37747403
Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway.
Investigative ophthalmology & visual science Sep, 2023 | Pubmed ID: 37768272
Comprehensive genetic analysis reveals the mutational landscape of ABCA4-associated retinal dystrophy in a Chinese cohort.
Gene Jan, 2024 | Pubmed ID: 37774808
The Evolution and Visual Prognosis of Glial Proliferation with Different Grades after Macular Hole Surgery: An Optical Coherence Tomography-Based Study.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde , 2023 | Pubmed ID: 37788659
Exome sequencing in retinal dystrophy patients reveals a novel candidate gene ER membrane protein complex subunit 3.
Heliyon Sep, 2023 | Pubmed ID: 37809982
Acute onset of decreased vision after violently vomiting: A case report.
European journal of ophthalmology Mar, 2024 | Pubmed ID: 37844619
Bietti's crystalline dystrophy: genotyping and deep qualitative and quantitative phenotyping in preparation for clinical trials.
The British journal of ophthalmology Jul, 2024 | Pubmed ID: 37963713
Genetic detection of two novel LRP5 pathogenic variants in patients with familial exudative vitreoretinopathy.
BMC ophthalmology Nov, 2023 | Pubmed ID: 38030997
CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids.
Stem cell research & therapy Dec, 2023 | Pubmed ID: 38049871
Fundus Tessellated Density of Pathologic Myopia.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) Nov-Dec 01, 2023 | Pubmed ID: 38079255
Timp1 Deletion Induces Anxiety-like Behavior in Mice.
Neuroscience bulletin Jun, 2024 | Pubmed ID: 38113013
Initiation of China Alliance of Research in High Myopia (CHARM): protocol for an AI-based multimodal high myopia research biobank.
BMJ open Dec, 2023 | Pubmed ID: 38151272
RNA fusion in human retinal development.
eLife Jan, 2024 | Pubmed ID: 38165397
Rationale and protocol paper for the Asia Pacific Network for inherited eye diseases.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) , 2024 | Pubmed ID: 38233300
Foveal Microstructure and Visual Outcomes after Pars Plana Vitrectomy in Patients with Different Types of Epiretinal Membrane Foveoschisis.
Ophthalmic research , 2024 | Pubmed ID: 38246146
Closure Grading and Visual Outcome in Patients with Large Idiopathic Macular Holes: A Spectral-Domain Optical Coherence Tomography Observation.
Ophthalmic research , 2024 | Pubmed ID: 38253044
Enhanced innate responses in microglia derived from retinoblastoma patient-specific iPSCs.
Glia May, 2024 | Pubmed ID: 38258347
Turning point of organoid transplantation: first-in-human trial of iPSC-derived retinal organoid grafting in patients with retinitis pigmentosa.
Science China. Life sciences May, 2024 | Pubmed ID: 38332215
A Novel Grading System for Diffuse Chorioretinal Atrophy in Pathologic Myopia.
Ophthalmology and therapy May, 2024 | Pubmed ID: 38441856
Modeling autosomal dominant retinitis pigmentosa by using patient-specific retinal organoids with a class-3 RHO mutation.
Experimental eye research Apr, 2024 | Pubmed ID: 38479725
Genetic control of DNA methylation is largely shared across European and East Asian populations.
Nature communications Mar, 2024 | Pubmed ID: 38548728
Daily Low-Level Red Light for Spherical Equivalent Error and Axial Length in Children With Myopia: A Randomized Clinical Trial.
JAMA ophthalmology Jun, 2024 | Pubmed ID: 38662345
Effects of fluorescent protein tdTomato on mouse retina.
Experimental eye research Jun, 2024 | Pubmed ID: 38663720
Patient-derived induced pluripotent stem cells with a mutation exhibit cell junction abnormalities and aberrant cellular differentiation potential.
World journal of stem cells May, 2024 | Pubmed ID: 38817331
Parallel comparison of ocular metrics in non-human primates with high myopia by LS900, ultrasonography and MRI-based 3D reconstruction.
Experimental eye research Jul, 2024 | Pubmed ID: 39029552
Deep Learning-Enabled Vasculometry Depicts Phased Lesion Patterns in High Myopia Progression.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) Jul, 2024 | Pubmed ID: 39053733
Trio-based whole-exome sequencing of 200 Chinese patients with keratoconus.
Experimental eye research Sep, 2024 | Pubmed ID: 39326774
ROCK inhibitor enhances mitochondrial transfer via tunneling nanotubes in retinal pigment epithelium.
Theranostics , 2024 | Pubmed ID: 39346535
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