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A Link between cholesterol levels and phenobarbital induction of cytochromes P450.
Biochemical and biophysical research communications Feb, 2002 | Pubmed ID: 11846416
NUBIScan, an in silico approach for prediction of nuclear receptor response elements.
Molecular endocrinology (Baltimore, Md.) Jun, 2002 | Pubmed ID: 12040014
Cholesterol and bile acids regulate xenosensor signaling in drug-mediated induction of cytochromes P450.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12045201
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2003 | Pubmed ID: 12764228
Induction of drug metabolism: the role of nuclear receptors.
Pharmacological reviews Dec, 2003 | Pubmed ID: 14657421
In silico approaches, and in vitro and in vivo experiments to predict induction of drug metabolism.
Drug news & perspectives Sep, 2003 | Pubmed ID: 14668938
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.
Genes & development Feb, 2004 | Pubmed ID: 14744933
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2004 | Pubmed ID: 15100410
Identification of the xenosensors regulating human 5-aminolevulinate synthase.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15178759
The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals.
Nuclear receptor 10, 2004 | Pubmed ID: 15479477
Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR.
Archives of biochemistry and biophysics Jan, 2005 | Pubmed ID: 15581595
Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids.
Archives of biochemistry and biophysics Feb, 2005 | Pubmed ID: 15629111
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.
Cell Jan, 2005 | Pubmed ID: 15680331
LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver.
Journal of lipid research Aug, 2005 | Pubmed ID: 15930522
Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.
Cell metabolism Apr, 2005 | Pubmed ID: 16054070
Metabolic control through the PGC-1 family of transcription coactivators.
Cell metabolism Jun, 2005 | Pubmed ID: 16054085
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha.
Cell Aug, 2005 | Pubmed ID: 16122419
Partnership of PGC-1alpha and HNF4alpha in the regulation of lipoprotein metabolism.
The Journal of biological chemistry May, 2006 | Pubmed ID: 16574644
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2006 | Pubmed ID: 16980408
PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17053067
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators.
Cell Oct, 2006 | Pubmed ID: 17055439
RANTES (regulated on activation, normal T cell expressed and secreted), inflammation, obesity, and the metabolic syndrome.
Circulation Feb, 2007 | Pubmed ID: 17325252
PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.
Genes & development Apr, 2007 | Pubmed ID: 17403779
A fundamental system of cellular energy homeostasis regulated by PGC-1alpha.
Proceedings of the National Academy of Sciences of the United States of America May, 2007 | Pubmed ID: 17470778
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17609368
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals.
The Journal of biological chemistry Oct, 2007 | Pubmed ID: 17702743
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.
The Journal of clinical investigation Nov, 2007 | Pubmed ID: 17932564
The role of exercise and PGC1alpha in inflammation and chronic disease.
Nature Jul, 2008 | Pubmed ID: 18650917
A high-mobility, low-cost phenotype defines human effector-memory CD8+ T cells.
Blood Jan, 2009 | Pubmed ID: 18845792
Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2008 | Pubmed ID: 19066218
The biology of PGC-1α and its therapeutic potential.
Trends in pharmacological sciences Jun, 2009 | Pubmed ID: 19446346
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha in muscle links metabolism to inflammation.
Clinical and experimental pharmacology & physiology Dec, 2009 | Pubmed ID: 19671064
For a pragmatic approach to exercise studies.
Journal of applied physiology (Bethesda, Md. : 1985) Jan, 2010 | Pubmed ID: 20066760
PGC-1α and myokines in the aging muscle - a mini-review.
Gerontology , 2011 | Pubmed ID: 20134150
Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α.
Journal of receptor and signal transduction research Dec, 2010 | Pubmed ID: 20178454
Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscle.
PloS one , 2010 | Pubmed ID: 20532042
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
Aging Jun, 2010 | Pubmed ID: 20606253
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.
The Journal of biological chemistry Oct, 2010 | Pubmed ID: 20716531
ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis.
PloS one , 2010 | Pubmed ID: 21042583
PGC-1 coactivators and the regulation of skeletal muscle fiber-type determination.
Cell metabolism Apr, 2011 | Pubmed ID: 21459315
Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity.
Biochemical and biophysical research communications Apr, 2011 | Pubmed ID: 21501593
Remodeling of calcium handling in skeletal muscle through PGC-1α: impact on force, fatigability, and fiber type.
American journal of physiology. Cell physiology Jan, 2012 | Pubmed ID: 21918181
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2011 | Pubmed ID: 22143799
PGC-1α determines light damage susceptibility of the murine retina.
PloS one , 2012 | Pubmed ID: 22348062
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