Vipul C. Chitalia

Jade-1, a candidate renal tumor suppressor that promotes apoptosis.

Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex.

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL.

Stromal endothelial cells directly influence cancer progression.

Matrix-embedded endothelial cells are protected from the uremic milieu.

Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1.

Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor.

Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis.

c-Cbl, a ubiquitin E3 ligase that targets active β-catenin: a novel layer of Wnt signaling regulation.

The c-Cbl ubiquitin ligase regulates nuclear β-catenin and angiogenesis by its tyrosine phosphorylation mediated through the Wnt signaling pathway.

The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia.

Racial differences in colorectal cancer survival at a safety net hospital.

Thrombotic Microangiopathy: A Multidisciplinary Team Approach.

Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.

Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans.

Association of Pathological Fibrosis With Renal Survival Using Deep Neural Networks.

Matrix-Embedded Endothelial Cells Attain a Progenitor-Like Phenotype.

c-Cbl Expression Correlates with Human Colorectal Cancer Survival and Its Wnt/β-Catenin Suppressor Function Is Regulated by Tyr371 Phosphorylation.

Unique aspects of peripheral artery disease in patients with chronic kidney disease.

Intrinsic coating morphology modulates acute drug transfer in drug-coated balloon therapy.

Towards minimally-invasive, quantitative assessment of chronic kidney disease using optical spectroscopy.

c-Cbl: An Important Regulator and a Target in Angiogenesis and Tumorigenesis.

Segmentation of Glomeruli Within Trichrome Images Using Deep Learning.

Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor-tissue factor axis.

c-Cbl targets PD-1 in immune cells for proteasomal degradation and modulates colorectal tumor growth.

Temporal and tissue-specific activation of aryl hydrocarbon receptor in discrete mouse models of kidney disease.

Haploinsufficiency of Casitas B-Lineage Lymphoma Augments the Progression of Colon Cancer in the Background of Adenomatous Polyposis Coli Inactivation.

Platelet Dysfunction and Thrombosis in JAK2-Mutated Primary Myelofibrotic Mice.

Molecular Mechanisms Underlying the Cardiovascular Toxicity of Specific Uremic Solutes.

Hyperthrombotic Milieu in COVID-19 Patients.

Uraemic solutes as therapeutic targets in CKD-associated cardiovascular disease.

Deep-Learning-Driven Quantification of Interstitial Fibrosis in Digitized Kidney Biopsies.

Machine Learning Applications in Nephrology: A Bibliometric Analysis Comparing Kidney Studies to Other Medicine Subspecialities.

Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD.

Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease.

Determinants of Hemodialysis Performance: Modeling Fluid and Solute Transport in Hollow-Fiber Dialyzers.

Janus Kinase Signaling Pathway and Its Role in COVID-19 Inflammatory, Vascular, and Thrombotic Manifestations.

Pharmacologic Manipulation of Late SV40 Factor Suppresses Wnt Signaling and Inhibits Growth of Allogeneic and Syngeneic Colon Cancer Xenografts.