Department of Plastic and Hand Surgery
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Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents.
Blood Apr, 2007 | Pubmed ID: 17164347
A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2007 | Pubmed ID: 17170374
Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation.
Arteriosclerosis, thrombosis, and vascular biology May, 2007 | Pubmed ID: 17322097
Subtractive single-chain antibody (scFv) phage-display: tailoring phage-display for high specificity against function-specific conformations of cell membrane molecules.
Nature protocols , 2007 | Pubmed ID: 18079705
Pathophysiological levels of soluble P-selectin mediate adhesion of leukocytes to the endothelium through Mac-1 activation.
Circulation research Nov, 2008 | Pubmed ID: 18818407
Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques.
Circulation research Jul, 2009 | Pubmed ID: 19520972
The aging lip: a comparative histological analysis of age-related changes in the upper lip complex.
Plastic and reconstructive surgery Aug, 2009 | Pubmed ID: 19644283
C-reactive protein: how conformational changes influence inflammatory properties.
Cell cycle (Georgetown, Tex.) Dec, 2009 | Pubmed ID: 19887916
A new evaluation tool for monitoring devices and its application to evaluate the implantable Doppler probe.
Journal of reconstructive microsurgery May, 2010 | Pubmed ID: 20143302
Monomeric C-reactive protein generation on activated platelets: the missing link between inflammation and atherothrombotic risk.
Trends in cardiovascular medicine Oct, 2009 | Pubmed ID: 20382347
Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage.
Journal of cellular and molecular medicine Jan, 2010 | Pubmed ID: 20414973
An algorithm for oncologic scalp reconstruction.
Plastic and reconstructive surgery Aug, 2010 | Pubmed ID: 20679829
The use of the vacuum-assisted closure in microsurgical reconstruction revisited: application in the reconstruction of the posttraumatic lower extremity.
Journal of reconstructive microsurgery Nov, 2010 | Pubmed ID: 20922656
A proteomic analysis of C-reactive protein stimulated THP-1 monocytes.
Proteome science , 2011 | Pubmed ID: 21219634
The diagnosis and treatment of soft tissue sarcomas of the limbs.
Deutsches Ärzteblatt international Jan, 2011 | Pubmed ID: 21286000
Retrospective analysis of 242 patients whose carpal tunnels were released using a one-port endoscopic procedure: superior results of early intervention.
Journal of plastic surgery and hand surgery Dec, 2010 | Pubmed ID: 21446811
Monitoring molecular changes induced by ischemia/reperfusion in human free muscle flap tissue samples.
Annals of plastic surgery Feb, 2012 | Pubmed ID: 21508818
Amyloid plaques dissociate pentameric to monomeric C-reactive protein: a novel pathomechanism driving cortical inflammation in Alzheimer's disease?
Brain pathology (Zurich, Switzerland) May, 2012 | Pubmed ID: 21951392
An integrated therapy concept for reduction of postoperative complications after resection of a panniculus morbidus.
Obesity surgery Apr, 2012 | Pubmed ID: 22108809
Ischemia-reperfusion injury leads to significant tissue damage in free flap surgery.
Plastic and reconstructive surgery Jan, 2012 | Pubmed ID: 22186547
Correspondence (letter to the editor): Body contouring surgery.
Deutsches Ärzteblatt international Feb, 2012 | Pubmed ID: 22368714
Technical facilitation of the fleur-de-lis abdominoplasty for symmetrical resection patterns in massive weight loss patients.
Plastic and reconstructive surgery Mar, 2012 | Pubmed ID: 22374036
Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction.
Cardiovascular research Jul, 2012 | Pubmed ID: 22798388
Pentameric CRP attenuates inflammatory effects of mmLDL by inhibiting mmLDL--monocyte interactions.
Atherosclerosis Oct, 2012 | Pubmed ID: 22901456
MicroRNAs in ischemia-reperfusion injury.
American journal of cardiovascular disease , 2012 | Pubmed ID: 22937493
Invited commentary.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Dec, 2011 | Pubmed ID: 21795131
Negative pressure wound therapy reduces the ischaemia/reperfusion-associated inflammatory response in free muscle flaps.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS May, 2012 | Pubmed ID: 22137686
A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties.
International immunology Aug, 2014 | Pubmed ID: 24844702
Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy.
Circulation Jul, 2014 | Pubmed ID: 24982116
Salvage procedures after failed facial reanimation surgery using the masseteric nerve as the motor nerve for free functional gracilis muscle transfer.
JAMA facial plastic surgery Sep-Oct, 2014 | Pubmed ID: 24994013
Comment on "Lengthening temporalis myoplasty and congenital facial paralysis".
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Apr, 2015 | Pubmed ID: 25661799
MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst.
Basic research in cardiology May, 2015 | Pubmed ID: 25916938
Identification of a blood-borne miRNA signature of synovial sarcoma.
Molecular cancer Aug, 2015 | Pubmed ID: 26250552
Microsurgical reconstruction of oncological scalp defects in the elderly.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Jul, 2016 | Pubmed ID: 27133193
Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7.
International journal of molecular sciences Oct, 2016 | Pubmed ID: 27783056
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
Nature communications Jan, 2017 | Pubmed ID: 28112148
Analysis of the ideal muscle weight of gracilis muscle transplants for facial reanimation surgery with regard to the donor nerve and outcome.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Apr, 2017 | Pubmed ID: 28159544
Levels of activated platelet-derived microvesicles in patients with soft tissue sarcoma correlate with an increased risk of venous thromboembolism.
BMC cancer Aug, 2017 | Pubmed ID: 28784104
Pedicled and free flaps for intrathoracic fistula management.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery Dec, 2017 | Pubmed ID: 29106507
Evaluation of the Implantable Doppler Probe for Free Flap Monitoring in Lower Limb Reconstruction.
Journal of reconstructive microsurgery Mar, 2018 | Pubmed ID: 29179224
Comparison of symmetry after smile reconstruction for flaccid facial paralysis with combined fascia lata grafts and functional gracilis transfer for static suspension or gracilis transfer alone.
Microsurgery Sep, 2018 | Pubmed ID: 29603352
Extracellular Vesicles: Packages Sent With Complement.
Frontiers in immunology , 2018 | Pubmed ID: 29696020
A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury.
Frontiers in immunology , 2018 | Pubmed ID: 29713320
Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes.
Frontiers in immunology , 2018 | Pubmed ID: 29946323
Pre-operative masseter muscle EMG activation during smile predicts synchronicity of smile development in facial palsy patients undergoing reanimation with the masseter nerve: A prospective cohort study.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Mar, 2019 | Pubmed ID: 30509736
Genotyping of circulating cell-free DNA enables noninvasive tumor detection in myxoid liposarcomas.
International journal of cancer 08, 2019 | Pubmed ID: 30779112
Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability.
Thrombosis and haemostasis Aug, 2019 | Pubmed ID: 31378855
Retrospective evaluation of diagnostic accuracy of free flap monitoring with the Cook-Swartz-Doppler probe in head and neck reconstruction.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery Dec, 2019 | Pubmed ID: 31810844
Efficacy and Safety of Microsurgery in Interdisciplinary Treatment of Sarcoma Affecting the Bone.
Frontiers in oncology , 2019 | Pubmed ID: 31850204
Combination of Static and Dynamic Techniques for Smile Reconstruction in Patients with Flaccid Facial Paralysis.
Plastic and reconstructive surgery. Global open Jul, 2019 | Pubmed ID: 31942352
C-Reactive Protein and Its Structural Isoforms: An Evolutionary Conserved Marker and Central Player in Inflammatory Diseases and Beyond.
Sub-cellular biochemistry , 2020 | Pubmed ID: 32189313
Reconstruction of Perineal Defects: A Comparison of the Myocutaneous Gracilis and the Gluteal Fold Flap in Interdisciplinary Anorectal Tumor Resection.
Frontiers in oncology , 2020 | Pubmed ID: 32435617
An Unbiased Flow Cytometry-Based Approach to Assess Subset-Specific Circulating Monocyte Activation and Cytokine Profile in Whole Blood.
Frontiers in immunology , 2021 | Pubmed ID: 33981302
Artificial Intelligence-Driven Video Analysis for Novel Outcome Measures After Smile Reanimation Surgery.
Facial plastic surgery & aesthetic medicine , 2022 | Pubmed ID: 34166082
Genetic Deficiency of TRAF5 Promotes Adipose Tissue Inflammation and Aggravates Diet-Induced Obesity in Mice.
Arteriosclerosis, thrombosis, and vascular biology 10, 2021 | Pubmed ID: 34348490
CRP Enhances the Innate Killing Mechanisms Phagocytosis and ROS Formation in a Conformation and Complement-Dependent Manner.
Frontiers in immunology , 2021 | Pubmed ID: 34447388
PY receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells.
Scientific reports Aug, 2021 | Pubmed ID: 34465804
Pharmacokinetic study of the novel phosphocholine derivative 3-dibutylaminopropylphosphonic acid by LC-MS coupling.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Dec, 2021 | Pubmed ID: 34798417
Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases.
Pharmacology & therapeutics Jul, 2022 | Pubmed ID: 35247517
Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas.
Cancers Apr, 2022 | Pubmed ID: 35565213
Age-related outcome of facial reanimation surgery using cross face nerve graft and gracilis free functional muscle transfer-A retrospective cohort study.
Microsurgery Sep, 2022 | Pubmed ID: 35579294
Oncological Safety and Recurrence in the Surgical Treatment of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma of the Scalp.
Cancers Jun, 2022 | Pubmed ID: 35740535
Autologous free tissue transfer in paediatric patient with a univentricular heart.
Interactive cardiovascular and thoracic surgery Jul, 2022 | Pubmed ID: 35792870
An Analysis of the Implantable Doppler Probe for Postoperative Free-Flap Monitoring and Risk Factor Analysis for Revision Surgery in Facial Reanimation Surgery.
Facial plastic surgery & aesthetic medicine , 2022 | Pubmed ID: 35998234
Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas.
International journal of molecular sciences Sep, 2022 | Pubmed ID: 36142126
C-reactive protein, immunothrombosis and venous thromboembolism.
Frontiers in immunology , 2022 | Pubmed ID: 36177015
A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
EMBO molecular medicine Jan, 2023 | Pubmed ID: 36468184
Newly identified axon types of the facial nerve unveil supplemental neural pathways in the innervation of the face.
Journal of advanced research Feb, 2023 | Pubmed ID: 36725185
Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.
Surgery Jun, 2023 | Pubmed ID: 37012145
Multiparametric magnetic resonance imaging for radiation therapy response monitoring in soft tissue sarcomas: a histology and MRI co-registration algorithm.
Theranostics , 2023 | Pubmed ID: 37056570
Correlation between facial vascularized composite allotransplantation rejection and laboratory markers: Insights from a retrospective study of eight patients.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Aug, 2023 | Pubmed ID: 37276734
Functional Outcome of Dual Reinnervation with Cross-Facial Nerve Graft and Masseteric Nerve Transfer for Facial Paralysis.
Plastic and reconstructive surgery Jun, 2024 | Pubmed ID: 37384874
Age-related outcomes of facial reanimation surgery using gracilis free functional muscle transfer innervated by the masseteric nerve: A retrospective cohort study.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Oct, 2023 | Pubmed ID: 37586310
Intravital Imaging of Leukocyte-Endothelial Interaction in Hindlimb Ischemia/Reperfusion Injury by Intravital Multiphoton Microscopy.
Methods in molecular biology (Clifton, N.J.) , 2024 | Pubmed ID: 37776451
Special Issue: Evidence-Based Diagnosis and Management of Facial Nerve Disorders.
Diagnostics (Basel, Switzerland) Sep, 2023 | Pubmed ID: 37835799
Non-invasive monitoring of neoadjuvant radiation therapy response in soft tissue sarcomas by multiparametric MRI and quantification of circulating tumor DNA-A study protocol.
PloS one , 2023 | Pubmed ID: 37910565
Secondary dynamic midface reanimation with gracilis free muscle transfer after failed reconstruction attempt: A 15-year experience.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS Dec, 2023 | Pubmed ID: 37925922
C-reactive protein orchestrates acute allograft rejection in vascularized composite allotransplantation via selective activation of monocyte subsets.
Journal of advanced research Jul, 2024 | Pubmed ID: 38992424
Shear-Sensing by C-Reactive Protein: Linking Aortic Stenosis and Inflammation.
Circulation research Nov, 2024 | Pubmed ID: 39421928
Antithrombotic Agents after Free Tissue Transfer in the Pediatric and Adolescent Population.
Journal of reconstructive microsurgery Nov, 2024 | Pubmed ID: 39496320
A conformational change of C-reactive protein drives neutrophil extracellular trap formation in inflammation.
BMC biology Jan, 2025 | Pubmed ID: 39773175
Microsurgical versus complex physical decongestive therapy for chronic breast cancer-related lymphoedema.
The Cochrane database of systematic reviews Feb, 2025 | Pubmed ID: 39945379
Artificial Intelligence in Facial Palsy Treatment: A Systematic Review and Recommendations.
Plastic and reconstructive surgery Mar, 2025 | Pubmed ID: 40099668
Birte Ohm*,1,
Julia Thomé*,2,
Thierry Christmann2,
Maike Lind2,
Yoshito Yamada3,
Andreas Spörlein4,
Laura Anna Schneider2,
Steffen U. Eisenhardt2,
Wolfgang Jungraithmayr1
1Department of Thoracic Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg,
2Department of Plastic and Hand Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg,
3Department of Thoracic Surgery, Kyoto University Hospital,
4Department of Otolaryngology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg
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