Department of Biochemistry
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Mammalian transcription factors in yeast: strangers in a familiar land.
Nature reviews. Molecular cell biology Jan, 2002 | Pubmed ID: 11823797
LMNA mutations in atypical Werner's syndrome.
Lancet Aug, 2003 | Pubmed ID: 12927431
Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit.
Molecular and cellular biology Jan, 2004 | Pubmed ID: 14701733
A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15210943
Sir2-independent life span extension by calorie restriction in yeast.
PLoS biology Sep, 2004 | Pubmed ID: 15328540
Large-scale identification in yeast of conserved ageing genes.
Mechanisms of ageing and development Jan, 2005 | Pubmed ID: 15610758
Substrate-specific activation of sirtuins by resveratrol.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15684413
A-type nuclear lamins, progerias and other degenerative disorders.
Mechanisms of ageing and development Apr, 2005 | Pubmed ID: 15722103
Genes determining yeast replicative life span in a long-lived genetic background.
Mechanisms of ageing and development Apr, 2005 | Pubmed ID: 15722108
LMNA mutations in progeroid syndromes.
Novartis Foundation symposium , 2005 | Pubmed ID: 15773755
Nuclear tumor suppressors in space and time.
Trends in cell biology Jul, 2005 | Pubmed ID: 15936946
HIV protease inhibitors block adipocyte differentiation independently of lamin A/C.
AIDS (London, England) Oct, 2005 | Pubmed ID: 16184025
The enigmatic role of Sir2 in aging.
Cell Nov, 2005 | Pubmed ID: 16286003
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science (New York, N.Y.) Nov, 2005 | Pubmed ID: 16293764
Increased life span due to calorie restriction in respiratory-deficient yeast.
PLoS genetics Nov, 2005 | Pubmed ID: 16311627
Extension of chronological life span in yeast by decreased TOR pathway signaling.
Genes & development Jan, 2006 | Pubmed ID: 16418483
Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation.
Genes & development Feb, 2006 | Pubmed ID: 16481476
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction".
Science (New York, N.Y.) Jun, 2006 | Pubmed ID: 16741098
Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrest.
Molecular and cellular biology Jul, 2006 | Pubmed ID: 16809772
Sirtuins in aging and age-related disease.
Cell Jul, 2006 | Pubmed ID: 16873059
Aging: progeria and the lamin connection.
Current biology : CB Aug, 2006 | Pubmed ID: 16920618
Lifespan extension in Caenorhabditis elegans by complete removal of food.
Aging cell Dec, 2006 | Pubmed ID: 17081160
Genome-wide identification of conserved longevity genes in yeast and worms.
Mechanisms of ageing and development Jan, 2007 | Pubmed ID: 17126379
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.
Aging cell Dec, 2006 | Pubmed ID: 17129213
The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function.
Genetics Jan, 2007 | Pubmed ID: 17151231
Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.
Nature reviews. Molecular cell biology May, 2007 | Pubmed ID: 17450177
Recent developments in yeast aging.
PLoS genetics May, 2007 | Pubmed ID: 17530929
Does resveratrol activate yeast Sir2 in vivo?
Aging cell Aug, 2007 | Pubmed ID: 17635418
Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2.
PloS one , 2007 | Pubmed ID: 17896003
Protein translation, 2007.
Aging cell Dec, 2007 | Pubmed ID: 17941970
Single-gene deletions that restore mating competence to diploid yeast.
FEMS yeast research Mar, 2008 | Pubmed ID: 17995956
A method for high-throughput quantitative analysis of yeast chronological life span.
The journals of gerontology. Series A, Biological sciences and medical sciences Feb, 2008 | Pubmed ID: 18314444
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.
Aging cell Jun, 2008 | Pubmed ID: 18331616
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome research Apr, 2008 | Pubmed ID: 18340043
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Cell Apr, 2008 | Pubmed ID: 18423200
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.
BMC developmental biology , 2008 | Pubmed ID: 18457595
Protein translation, 2008.
Aging cell Dec, 2008 | Pubmed ID: 18782345
Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53.
Molecular biology of the cell Dec, 2008 | Pubmed ID: 18843043
Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.
PloS one , 2008 | Pubmed ID: 19030232
A-type nuclear lamins act as transcriptional repressors when targeted to promoters.
Experimental cell research Apr, 2009 | Pubmed ID: 19272320
A molecular mechanism of chronological aging in yeast.
Cell cycle (Georgetown, Tex.) Apr, 2009 | Pubmed ID: 19305133
Histone H4 lysine 16 acetylation regulates cellular lifespan.
Nature Jun, 2009 | Pubmed ID: 19516333
The TOR pathway comes of age.
Biochimica et biophysica acta Oct, 2009 | Pubmed ID: 19539012
Ageing: A midlife longevity drug?
Nature Jul, 2009 | Pubmed ID: 19606132
Hot topics in aging research: protein translation, 2009.
Aging cell Dec, 2009 | Pubmed ID: 19747234
Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.
Biophysical journal Sep, 2009 | Pubmed ID: 19751676
Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.
The journals of gerontology. Series A, Biological sciences and medical sciences Dec, 2009 | Pubmed ID: 19776218
Translate this ... during dietary restriction.
Cell metabolism Oct, 2009 | Pubmed ID: 19808017
Cell-extrinsic defective lymphocyte development in Lmna(-/-) mice.
PloS one , 2010 | Pubmed ID: 20405040
Progeria syndromes and ageing: what is the connection?
Nature reviews. Molecular cell biology Aug, 2010 | Pubmed ID: 20651707
Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice.
Aging cell Oct, 2010 | Pubmed ID: 20726853
Old yeast can't handle the noise.
Molecular cell Sep, 2010 | Pubmed ID: 20832716
TOR on the brain.
Experimental gerontology Feb-Mar, 2011 | Pubmed ID: 20849946
TOR and ageing: a complex pathway for a complex process.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jan, 2011 | Pubmed ID: 21115526
Hot topics in aging research: protein translation and TOR signaling, 2010.
Aging cell Apr, 2011 | Pubmed ID: 21176090
Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast.
Cell cycle (Georgetown, Tex.) Jan, 2011 | Pubmed ID: 21191185
Asymmetric segregation: the shape of things to come?
Current biology : CB Feb, 2011 | Pubmed ID: 21334292
A genomic analysis of chronological longevity factors in budding yeast.
Cell cycle (Georgetown, Tex.) May, 2011 | Pubmed ID: 21447998
Decreased proliferation kinetics of mouse myoblasts overexpressing FRG1.
PloS one , 2011 | Pubmed ID: 21603621
Trinations aging symposium.
Mechanisms of ageing and development Jun-Jul, 2011 | Pubmed ID: 21771608
Aged worms erase epigenetic history.
Cell metabolism Aug, 2011 | Pubmed ID: 21803283
Sir2 deletion prevents lifespan extension in 32 long-lived mutants.
Aging cell Dec, 2011 | Pubmed ID: 21902802
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae.
PLoS genetics Sep, 2011 | Pubmed ID: 21931558
Genome-wide analysis of yeast aging.
Sub-cellular biochemistry , 2012 | Pubmed ID: 22094426
The Buck Institute: An inside look.
Cell cycle (Georgetown, Tex.) Dec, 2011 | Pubmed ID: 22157188
A new chronological survival assay in mammalian cell culture.
Cell cycle (Georgetown, Tex.) Jan, 2012 | Pubmed ID: 22214665
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