Department of Medicine,
Division of Diabetes,
Endocrinology & Metabolism,
Diabetes & Endocrinology Research Center,
Department of Molecular & Cellular Biology,
Division of Diabetes, Endocrinology & Metabolism, Diabetes & Endocrinology Research Center
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Recent advances in liver-directed gene therapy for dyslipidemia.
Current atherosclerosis reports May, 2002 | Pubmed ID: 11931717
Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia.
Circulation Jun, 2003 | Pubmed ID: 12742997
Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice.
Gene Mar, 2004 | Pubmed ID: 14980712
Liver-directed gene therapy for dyslipidemia and diabetes.
Current atherosclerosis reports May, 2004 | Pubmed ID: 15068745
Targeting site-specific chromosome integration.
Acta biochimica Polonica , 2005 | Pubmed ID: 15940345
Inhibition and regression of atherosclerotic lesions.
Acta biochimica Polonica , 2005 | Pubmed ID: 15940346
Construction and characterization of helper-dependent adenoviral vectors for sustained in vivo gene therapy.
Methods in molecular medicine , 2005 | Pubmed ID: 16028693
Regulatable atrial natriuretic peptide gene therapy for hypertension.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2005 | Pubmed ID: 16162668
Essential role of Smad3 in angiotensin II-induced vascular fibrosis.
Circulation research Apr, 2006 | Pubmed ID: 16556868
Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis.
Circulation May, 2006 | Pubmed ID: 16702468
Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice.
The American journal of pathology Jun, 2006 | Pubmed ID: 16723719
Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18252823
Helper-dependent adenoviral vectors.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] Feb, 2005 | Pubmed ID: 18265354
Helper-dependent adenoviral vectors.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] Nov, 2005 | Pubmed ID: 18428374
Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2008 | Pubmed ID: 18781141
Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity.
Arteriosclerosis, thrombosis, and vascular biology Jun, 2009 | Pubmed ID: 19286630
Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes.
Developmental cell Mar, 2009 | Pubmed ID: 19289082
A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.
Brain research Jun, 2009 | Pubmed ID: 19393635
Direct observation of Gouy phase shift in a propagating optical vortex.
Optics express Sep, 2006 | Pubmed ID: 19529215
DRG-targeted helper-dependent adenoviruses mediate selective gene delivery for therapeutic rescue of sensory neuronopathies in mice.
The Journal of clinical investigation Jul, 2009 | Pubmed ID: 19603551
ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene.
Journal of the American College of Cardiology Jul, 2009 | Pubmed ID: 19608030
Liver-specific expression of an exogenous gene controlled by human apolipoprotein A-I promoter.
International journal of pharmaceutics Oct, 2010 | Pubmed ID: 20656001
Interleukin-7 induces recruitment of monocytes/macrophages to endothelium.
European heart journal Jul, 2011 | Pubmed ID: 21804111
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy.
Human molecular genetics Jan, 2012 | Pubmed ID: 22027994
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