Department of Biomedical Engineering,
Vanderbilt Institute for Nanoscale Science & Engineering,
School of Engineering
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Quantitative microcomputed tomography analysis of collateral vessel development after ischemic injury.
American journal of physiology. Heart and circulatory physiology Jul, 2004 | Pubmed ID: 15016633
Impaired angiogenesis, early callus formation, and late stage remodeling in fracture healing of osteopontin-deficient mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Feb, 2007 | Pubmed ID: 17087627
Host immune competence and local ischemia affects the functionality of engineered vasculature.
Microcirculation (New York, N.Y. : 1994) Feb, 2007 | Pubmed ID: 17365663
The role of osteopontin in recovery from hind limb ischemia.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2008 | Pubmed ID: 18006856
3D imaging of tissue integration with porous biomaterials.
Biomaterials Oct, 2008 | Pubmed ID: 18635260
Development of a novel endosomolytic diblock copolymer for siRNA delivery.
Journal of controlled release : official journal of the Controlled Release Society Feb, 2009 | Pubmed ID: 18973780
Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Oct, 2009 | Pubmed ID: 19338032
Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer.
Molecular pharmaceutics Apr, 2010 | Pubmed ID: 19968323
Sustained VEGF delivery via PLGA nanoparticles promotes vascular growth.
American journal of physiology. Heart and circulatory physiology Jun, 2010 | Pubmed ID: 20228260
Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy.
Bioconjugate chemistry Dec, 2010 | Pubmed ID: 21043513
Delivery of intracellular-acting biologics in pro-apoptotic therapies.
Current pharmaceutical design , 2011 | Pubmed ID: 21348831
RAFT-synthesized graft copolymers that enhance pH-dependent membrane destabilization and protein circulation times.
Journal of controlled release : official journal of the Controlled Release Society Oct, 2011 | Pubmed ID: 21699931
Sustained local delivery of siRNA from an injectable scaffold.
Biomaterials Feb, 2012 | Pubmed ID: 22061489
Poly(PS-b-DMA) micelles for reactive oxygen species triggered drug release.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2012 | Pubmed ID: 22889714
Intracellular Delivery and Trafficking Dynamics of a Lymphoma-Targeting Antibody-Polymer Conjugate.
Molecular pharmaceutics Nov, 2012 | Pubmed ID: 23075320
Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status.
Journal of biomedical optics Nov, 2012 | Pubmed ID: 23117810
Macrophage-Specific RNA Interference Targeting via "Click", Mannosylated Polymeric Micelles.
Molecular pharmaceutics Mar, 2013 | Pubmed ID: 23331322
Dual pH- and temperature-responsive microparticles for protein delivery to ischemic tissues.
Acta biomaterialia Feb, 2013 | Pubmed ID: 23402764
Nanocarriers for dual delivery of doxorubicin and siRNA to overcome multidrug resistance.
Nanomedicine (London, England) Mar, 2013 | Pubmed ID: 23477333
Quantitative optical imaging of vascular response in vivo in a model of peripheral arterial disease.
American journal of physiology. Heart and circulatory physiology Oct, 2013 | Pubmed ID: 23955718
Balancing cationic and hydrophobic content of PEGylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo.
ACS nano Oct, 2013 | Pubmed ID: 24041122
Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo.
Advanced materials (Deerfield Beach, Fla.) Jan, 2014 | Pubmed ID: 24338842
A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species.
Biomaterials Apr, 2014 | Pubmed ID: 24491510
siRNA Delivery from an Injectable Scaffold for Wound Therapy.
Advances in wound care Apr, 2013 | Pubmed ID: 24527332
In vivo imaging of nanoparticle delivery and tumor microvasculature with multimodal optical coherence tomography.
Biomedical optics express Jun, 2014 | Pubmed ID: 24940536
In situ synthesis of peptide nucleic acids in porous silicon for drug delivery and biosensing.
Bioconjugate chemistry Jul, 2014 | Pubmed ID: 24949894
Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery.
Advanced functional materials Jun, 2013 | Pubmed ID: 25214828
Cell protective, ABC triblock polymer-based thermoresponsive hydrogels with ROS-triggered degradation and drug release.
Journal of the American Chemical Society Oct, 2014 | Pubmed ID: 25254509
Future nanomedicine for the diagnosis and treatment of osteoarthritis.
Nanomedicine (London, England) Jul, 2014 | Pubmed ID: 25405797
Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery.
Biomacromolecules Jan, 2015 | Pubmed ID: 25414930
Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers.
Biomaterials Jan, 2015 | Pubmed ID: 25453977
ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.
Biomaterials Feb, 2015 | Pubmed ID: 25522975
Enhanced Performance of Plasmid DNA Polyplexes Stabilized by a Combination of Core Hydrophobicity and Surface PEGylation.
Journal of materials chemistry. B, Materials for biology and medicine Dec, 2014 | Pubmed ID: 25530856
MiRNA inhibition in tissue engineering and regenerative medicine.
Advanced drug delivery reviews Jul, 2015 | Pubmed ID: 25553957
Quantifying the vascular response to ischemia with speckle variance optical coherence tomography.
Biomedical optics express Dec, 2014 | Pubmed ID: 25574425
Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles.
Journal of biomedical materials research. Part A Sep, 2015 | Pubmed ID: 25641816
A transient cell-shielding method for viable MSC delivery within hydrophobic scaffolds polymerized in situ.
Biomaterials Jun, 2015 | Pubmed ID: 25907036
Particle-based technologies for osteoarthritis detection and therapy.
Drug delivery and translational research Apr, 2016 | Pubmed ID: 25990835
Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.
ACS nano Jun, 2015 | Pubmed ID: 26004140
MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.
Science translational medicine Jun, 2015 | Pubmed ID: 26062847
Shape-engineered multifunctional porous silicon nanoparticles by direct imprinting.
Nanotechnology Jul, 2015 | Pubmed ID: 26081802
Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.
The Journal of clinical investigation Aug, 2015 | Pubmed ID: 26214526
Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.
The Journal of clinical investigation Sep, 2015 | Pubmed ID: 26325037
Technologies for controlled, local delivery of siRNA.
Journal of controlled release : official journal of the Controlled Release Society Nov, 2015 | Pubmed ID: 26476177
High conversion of HAuCl4 into gold nanorods: A re-seeding approach.
Journal of colloid and interface science Feb, 2016 | Pubmed ID: 26550780
Hydrolytic charge-reversal of PEGylated polyplexes enhances intracellular un-packaging and activity of siRNA.
Journal of biomedical materials research. Part A Apr, 2016 | Pubmed ID: 26691570
Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer.
Biomaterials Jun, 2016 | Pubmed ID: 27043768
Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.
Biomaterials Aug, 2016 | Pubmed ID: 27163624
Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti-MicroRNA Therapies.
Advanced materials (Deerfield Beach, Fla.) Sep, 2016 | Pubmed ID: 27383910
Local Delivery of PHD2 siRNA from ROS-Degradable Scaffolds to Promote Diabetic Wound Healing.
Advanced healthcare materials Sep, 2016 | Pubmed ID: 27717176
Subfailure Overstretch Injury Leads to Reversible Functional Impairment and Purinergic P2X7 Receptor Activation in Intact Vascular Tissue.
Frontiers in bioengineering and biotechnology , 2016 | Pubmed ID: 27747211
Brian C. Evans*,1,2,
Christopher E. Nelson*,1,2,
Shann S. Yu*,1,2,
Kelsey R. Beavers2,3,
Arnold J. Kim1,
Hongmei Li1,2,
Heather M. Nelson4,
Todd D. Giorgio1,2,5,6,
Craig L. Duvall1,2
1Department of Biomedical Engineering, Vanderbilt University,
2Vanderbilt Institute for Nanoscale Science & Engineering, Vanderbilt University,
3Interdisciplinary Materials Science Program, Vanderbilt University,
4Monroe Carell Jr. Children's Hospital, Vanderbilt University Medical Center,
5Department of Chemical & Biomolecular Engineering, Vanderbilt University,
6Department of Cancer Biology, Vanderbilt University
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