Institute of Bio- and Geosciences,
IBG-1: Biotechnology,
Institute of Bio- and Geosciences, IBG-1: Biotechnology
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Modeling and simulation: tools for metabolic engineering.
Journal of biotechnology Mar, 2002 | Pubmed ID: 11792451
An introduction to 13C metabolic flux analysis.
Genetic engineering , 2002 | Pubmed ID: 12416307
MMT--a pathway modeling tool for data from rapid sampling experiments.
In silico biology , 2002 | Pubmed ID: 12611627
Metabolic isotopomer labeling systems. Part II: structural flux identifiability analysis.
Mathematical biosciences Jun, 2003 | Pubmed ID: 12711410
New tools for mass isotopomer data evaluation in (13)C flux analysis: mass isotope correction, data consistency checking, and precursor relationships.
Biotechnology and bioengineering Feb, 2004 | Pubmed ID: 14748080
Serial 13C-based flux analysis of an L-phenylalanine-producing E. coli strain using the sensor reactor.
Biotechnology progress May-Jun, 2004 | Pubmed ID: 15176872
Investigating the dynamic behavior of biochemical networks using model families.
Bioinformatics (Oxford, England) Apr, 2005 | Pubmed ID: 15604106
From stationary to instationary metabolic flux analysis.
Advances in biochemical engineering/biotechnology , 2005 | Pubmed ID: 15791936
Emerging Corynebacterium glutamicum systems biology.
Journal of biotechnology Jun, 2006 | Pubmed ID: 16406159
Interpretation of metabolic flux maps by limitation potentials and constrained limitation sensitivities.
Biotechnology and bioengineering Jun, 2006 | Pubmed ID: 16596665
Experimental design principles for isotopically instationary 13C labeling experiments.
Biotechnology and bioengineering Jun, 2006 | Pubmed ID: 16598793
Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions.
Metabolic engineering Nov, 2006 | Pubmed ID: 16890470
Metabolic flux analysis at ultra short time scale: isotopically non-stationary 13C labeling experiments.
Journal of biotechnology Apr, 2007 | Pubmed ID: 17207877
Nondestructive and noncontact method for determining the spring constant of rectangular cantilevers.
The Review of scientific instruments Apr, 2007 | Pubmed ID: 17477668
Fluxomics: mass spectrometry versus quantitative imaging.
Current opinion in plant biology Jun, 2007 | Pubmed ID: 17481942
The thermodynamic meaning of metabolic exchange fluxes.
Biophysical journal Sep, 2007 | Pubmed ID: 17526563
The topology of metabolic isotope labeling networks.
BMC bioinformatics , 2007 | Pubmed ID: 17727715
Visualizing regulatory interactions in metabolic networks.
BMC biology , 2007 | Pubmed ID: 17939866
13C labeling experiments at metabolic nonstationary conditions: an exploratory study.
BMC bioinformatics , 2008 | Pubmed ID: 18366666
Translating biochemical network models between different kinetic formats.
Metabolic engineering Mar, 2009 | Pubmed ID: 19013536
Modeling Languages for Biochemical Network Simulation: Reaction vs Equation Based Approaches.
Advances in biochemical engineering/biotechnology , 2010 | Pubmed ID: 20309675
Stationary versus non-stationary (13)C-MFA: a comparison using a consistent dataset.
Journal of biotechnology Jul, 2011 | Pubmed ID: 20638432
Mechanistic pathway modeling for industrial biotechnology: challenging but worthwhile.
Current opinion in biotechnology Oct, 2011 | Pubmed ID: 21353523
Visualizing multi-omics data in metabolic networks with the software Omix: a case study.
Bio Systems Aug, 2011 | Pubmed ID: 21575673
The benefits of being transient: isotope-based metabolic flux analysis at the short time scale.
Applied microbiology and biotechnology Sep, 2011 | Pubmed ID: 21732247
Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum.
Applied and environmental microbiology Sep, 2011 | Pubmed ID: 21784914
Collisional fragmentation of central carbon metabolites in LC-MS/MS increases precision of ¹³C metabolic flux analysis.
Biotechnology and bioengineering Mar, 2012 | Pubmed ID: 22012626
Optical sensors for monitoring dynamic changes of intracellular metabolite levels in mammalian cells.
Nature protocols Nov, 2011 | Pubmed ID: 22036884
Tailoring a stabilized variant of hydroxynitrile lyase from Arabidopsis thaliana.
Chembiochem : a European journal of chemical biology Apr, 2012 | Pubmed ID: 22378361
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.
Lab on a chip May, 2012 | Pubmed ID: 22511122
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.
Biotechnology and bioengineering Jan, 2013 | Pubmed ID: 22890752
Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms.
Microbial cell factories , 2012 | Pubmed ID: 22963408
13CFLUX2--high-performance software suite for (13)C-metabolic flux analysis.
Bioinformatics (Oxford, England) Jan, 2013 | Pubmed ID: 23110970
Influence of Organic Solvents on Enzymatic Asymmetric Carboligations.
Advanced synthesis & catalysis Oct, 2012 | Pubmed ID: 23349644
Combined fluxomics and transcriptomics analysis of glucose catabolism via a partially cyclic pentose phosphate pathway in Gluconobacter oxydans 621H.
Applied and environmental microbiology Apr, 2013 | Pubmed ID: 23377928
Metabolic isotopomer labeling systems. Part III: path tracing.
Mathematical biosciences Jul, 2013 | Pubmed ID: 23507460
Isotopically non-stationary metabolic flux analysis: complex yet highly informative.
Current opinion in biotechnology Dec, 2013 | Pubmed ID: 23623747
Simultaneous utilization of glucose and gluconate in Penicillium chrysogenum during overflow metabolism.
Biotechnology and bioengineering Dec, 2013 | Pubmed ID: 23775209
13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis.
Chemistry & biology Aug, 2013 | Pubmed ID: 23911587
Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium.
Biotechnology and bioengineering Aug, 2013 | Pubmed ID: 23996851
Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes.
Journal of microbiological methods Sep, 2013 | Pubmed ID: 24041615
Assessment of robustness against dissolved oxygen/substrate oscillations for C. glutamicum DM1933 in two-compartment bioreactor.
Bioprocess and biosystems engineering Nov, 2013 | Pubmed ID: 24218302
Process inhomogeneity leads to rapid side product turnover in cultivation of Corynebacterium glutamicum.
Microbial cell factories Jan, 2014 | Pubmed ID: 24410842
Single-cell microfluidics: opportunity for bioprocess development.
Current opinion in biotechnology Oct, 2014 | Pubmed ID: 24642389
Developing a new production host from a blueprint: Bacillus pumilus as an industrial enzyme producer.
Microbial cell factories Mar, 2014 | Pubmed ID: 24661794
Quantitative metabolomics: a phantom?
Trends in biotechnology May, 2014 | Pubmed ID: 24708998
Error propagation analysis for quantitative intracellular metabolomics.
Metabolites Nov, 2012 | Pubmed ID: 24957773
Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum.
Bioprocess and biosystems engineering Dec, 2014 | Pubmed ID: 24981020
An evaluation of genetically encoded FRET-based biosensors for quantitative metabolite analyses in vivo.
Journal of biotechnology Dec, 2014 | Pubmed ID: 25107505
Chassis organism from Corynebacterium glutamicum--a top-down approach to identify and delete irrelevant gene clusters.
Biotechnology journal Feb, 2015 | Pubmed ID: 25139579
Visual workflows for 13C-metabolic flux analysis.
Bioinformatics (Oxford, England) Feb, 2015 | Pubmed ID: 25297067
Engineering of Corynebacterium glutamicum for minimized carbon loss during utilization of D-xylose containing substrates.
Journal of biotechnology Dec, 2014 | Pubmed ID: 25304460
Absolute quantification of Corynebacterium glutamicum glycolytic and anaplerotic enzymes by QconCAT.
Journal of proteomics Jan, 2015 | Pubmed ID: 25451015
How to measure metabolic fluxes: a taxonomic guide for (13)C fluxomics.
Current opinion in biotechnology Aug, 2015 | Pubmed ID: 25531408
Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping.
Microbial cell factories Mar, 2015 | Pubmed ID: 25888907
The effect of composition on diffusion of macromolecules in a crowded environment.
Physical biology May, 2015 | Pubmed ID: 26020120
Live cell imaging of SOS and prophage dynamics in isogenic bacterial populations.
Molecular microbiology Nov, 2015 | Pubmed ID: 26235130
Vizardous: interactive analysis of microbial populations with single cell resolution.
Bioinformatics (Oxford, England) Dec, 2015 | Pubmed ID: 26261223
Modeling and CFD simulation of nutrient distribution in picoliter bioreactors for bacterial growth studies on single-cell level.
Lab on a chip Nov, 2015 | Pubmed ID: 26345659
Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Dec, 2015 | Pubmed ID: 26348020
Cutting the Gordian Knot: Identifiability of anaplerotic reactions in Corynebacterium glutamicum by means of (13) C-metabolic flux analysis.
Biotechnology and bioengineering Mar, 2016 | Pubmed ID: 26375179
(13)C Tracers for Glucose Degrading Pathway Discrimination in Gluconobacter oxydans 621H.
Metabolites Sep, 2015 | Pubmed ID: 26404385
Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester.
PloS one , 2015 | Pubmed ID: 26513257
Photocaged Arabinose: A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression.
Chembiochem : a European journal of chemical biology Feb, 2016 | Pubmed ID: 26677142
A scientific workflow framework for (13)C metabolic flux analysis.
Journal of biotechnology Aug, 2016 | Pubmed ID: 26721184
Discrete-continuous reaction-diffusion model with mobile point-like sources and sinks.
The European physical journal. E, Soft matter Jan, 2016 | Pubmed ID: 26830760
Automation of a Nile red staining assay enables high throughput quantification of microalgal lipid production.
Microbial cell factories Feb, 2016 | Pubmed ID: 26861538
μMORE: A microfluidic magnetic oscillation reactor for accelerated parameter optimization in biocatalysis.
Journal of biotechnology Aug, 2016 | Pubmed ID: 27288595
Design and validation of a parallelized micro-photobioreactor enabling phototrophic bioprocess development at elevated throughput.
Biotechnology and bioengineering Jan, 2017 | Pubmed ID: 27424867
Time-resolved, single-cell analysis of induced and programmed cell death via non-invasive propidium iodide and counterstain perfusion.
Scientific reports Sep, 2016 | Pubmed ID: 27580964
Metabolic profile of 1,5-diaminopentane producing Corynebacterium glutamicum under scale-down conditions: Blueprint for robustness to bioreactor inhomogeneities.
Biotechnology and bioengineering Mar, 2017 | Pubmed ID: 27641904
Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments.
PloS one , 2016 | Pubmed ID: 27661996
A Toolbox of Genetically Encoded FRET-Based Biosensors for Rapid l-Lysine Analysis.
Sensors (Basel, Switzerland) Sep, 2016 | Pubmed ID: 27690044
Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum.
Microbial cell factories Dec, 2016 | Pubmed ID: 27927208
Comparative evaluation of phototrophic microtiter plate cultivation against laboratory-scale photobioreactors.
Bioprocess and biosystems engineering May, 2017 | Pubmed ID: 28101644
A framework for accelerated phototrophic bioprocess development: integration of parallelized microscale cultivation, laboratory automation and Kriging-assisted experimental design.
Biotechnology for biofuels , 2017 | Pubmed ID: 28163783
Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level.
Microbial biotechnology Jul, 2017 | Pubmed ID: 28371389
Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation.
Biotechnology and bioengineering Sep, 2017 | Pubmed ID: 28436005
Miniaturized and automated adaptive laboratory evolution: Evolving Corynebacterium glutamicum towards an improved d-xylose utilization.
Bioresource technology Dec, 2017 | Pubmed ID: 28552568
Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity.
Metabolic engineering Jul, 2017 | Pubmed ID: 28645641
To be certain about the uncertainty: Bayesian statistics for 13 C metabolic flux analysis.
Biotechnology and bioengineering Nov, 2017 | Pubmed ID: 28695999
Corynebacterium glutamicum Chassis C1*: Building and Testing a Novel Platform Host for Synthetic Biology and Industrial Biotechnology.
ACS synthetic biology Aug, 2017 | Pubmed ID: 28803482
pH fluctuations imperil the robustness of C. glutamicum to short term oxygen limitation.
Journal of biotechnology Oct, 2017 | Pubmed ID: 28837821
Laboratory scale photobiotechnology - Current trends and future perspectives.
FEMS microbiology letters Nov, 2017 | Pubmed ID: 29126108
Automated growth rate determination in high-throughput microbioreactor systems.
BMC research notes Nov, 2017 | Pubmed ID: 29178966
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