BioMarin Pharmaceutical Inc

1 ARTICLES PUBLISHED IN JoVE

image

Immunology and Infection

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
Ruby Cheung 1, Gregory W. deHart 1, Lynne Jesaitis 1, Stephen J. Zoog 1, Andrew C. Melton 1
1BioMarin Pharmaceutical Inc

Here we present a cell-based flow cytometry method to detect neutralizing antibodies or other factors that interfere with the cellular uptake of enzyme replacement therapies in a human matrix, such as cerebral spinal fluid (CSF) or human serum.

JoVE Logo

개인 정보 보호

이용 약관

정책

연구

교육

JoVE 소개

Copyright © 2025 MyJoVE Corporation. 판권 소유