A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue

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1.9K Views

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13:45 min

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November 11th, 2022

DOI :

10.3791/64334-v

November 11th, 2022

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Hanneke Crielaard¹, Su Guvenir Torun¹, Tamar B. Wissing¹^,², Pablo de Miguel Muñoz¹^,³, Gert-Jan Kremers⁴, Frank J. H. Gijsen¹^,³, Kim Van Der Heiden¹^,², Ali C. Akyildiz¹^,³

¹Department of Biomedical Engineering, Erasmus Medical Center, ²Department of Biomedical Engineering, Eindhoven University of Technology, ³Department of Biomechanical Engineering, Delft University of Technology, ⁴Erasmus Optical Imaging Center, Erasmus Medical Center

Samenvatting

Meer video's verkennen

Collagen Structure

Mechanical Properties

Atherosclerotic Plaque

Tissue Assessment

Mechanical Testing

Imaging Technique

Sample Geometry

Tensile Testing Device

Sample Preparation

Multiphoton Microscopy

Clinical Events

Hoofdstukken in deze video

0:05

Introduction

0:46

Tissue Sample Preparation and Multiphoton Microscopy (MPM) Imaging

6:04

Mechanical Testing

7:55

Data Analysis

11:22

Results: Studying Heterogeneous Structural and Mechanical Atherosclerotic Plaque Properties

13:06

Conclusion

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