Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors
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6.1K Views
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08:45 min
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July 17th, 2020
DOI :
July 17th, 2020
•Rozdziały w tym wideo
0:04
Introduction
1:04
Transfection of HEK293T Cells
2:36
Incubation of Cells with SHP2 Inhibitors
5:11
Isothermal or Thermal Profile Gradient Heat Pulse
6:01
Results: Cellular Target Engagement of Allosteric SHP2 Inhibitors with SHP2-WT and SHP2-E76K Proteins
8:03
Conclusion
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