A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes

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2.8K Views

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07:37 min

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October 28th, 2021

DOI :

10.3791/62445-v

October 28th, 2021

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Yong Gyu Lee¹^,², Jung-Lye Kim¹^,², Andre F. Palmer³, Brenda F. Reader⁴, Jianjie Ma¹, Sylvester M. Black²^,⁴, Bryan A. Whitson¹^,²

¹Department of Surgery Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, ²The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory, The Ohio State University College of Medicine, ³William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University, ⁴Comprehensive Transplant Center, The Ohio State University Wexner Medical Center

Podsumowanie

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Rat Lung Transplantation

Surgical Device Setup

Isoflurane

Anesthesia Machine

Angio catheter

Midline Skin Incision

Endotracheal Intubation

Rozdziały w tym wideo

0:04

Introduction

0:45

Initial Setup

2:53

Donor Lung Warm Ischemia and Procurement

4:14

Recipient Rat Preparation and Anastomoses

6:12

Reperfusion

6:35

Results: The Wet‐To‐Dry Weight Ratio of The Lobes

6:55

Conclusion

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