Department of Obstetrics and Gynaecology
After medical education and training with honors, Ronald devoted his career to medical research in Department of Obstetrics and Gynaecology at The Chinese University of Hong Kong (CUHK). Ronald conducted clinical and medical research in Prince of Wales Hospital, CUHK, Hong Kong and Westmead Hospital, University of Sydney, Australia, and was awarded PhD degree in Surgical Science with distinction.
Ronald held international scholarships and awards from Deutscher Akademischer Austausch Dienst and Japan Society for the Promotion of Science for his postdoctoral training in molecular biology, genetics and bioinformatics at Humboldt University zü Berlin in Germany, National Institute of Genetics in Japan, and University of Oxford in UK; and also from Roche, International Federation of Clinical Chemistry and Laboratory Medicine, American Association for Clinical Chemistry, Human Genome Organisation, Asian-Pacific Federation of Clinical Biochemists, European Societies for Clinical Chemistry and Laboratory Medicine, International Society for Immunology of Reproduction, International Federation of Placental Associations and Society for Gynecologic Investigation for his professional development in clinical biochemistry and molecular pathology in preeclampsia. Ronald also received visiting professorship to Children’s Medical Research Institute at University of Sydney in Australia for embryology research; Jackson Laboratory in United State and The 21st Century COE Programme, Chromosome Engineering Technology in Japan for stem cell research; Cochrane Pregnancy and Childbirth Group in Oxford for systematic reviews; and University of Oxford in Oxford and Harvard Medical School in Boston for endometriosis research. Lately Ronald develop his interest in medical genetics, establish Prenatal Genetics Diagnosis Centre, and was honored with a Ronpaku Fellowship to obtain his second PhD degree in Genetics with distinction.
Ronald had published over 25 book chapters, 120 peer-reviewed papers and 250 conference abstracts on many acclaimed journals including Gene Dev, Proc Natl Acad Sci U S A, Hum Reprod Update, Angiogenesis, Cell Research, J Biol Chem, Free Radical Biol Med, Mol Hum Reprod, Hum Reprod, and Fertil Steril. His success in fetal medicine research has earned him multiple local and international scholarships and awards. He was appointed to the editorial boards and review panels of many important research funding agents and journals.
Innate immune response by ficolin binding in apoptotic placenta is associated with the clinical syndrome of preeclampsia.
Clinical chemistry Jan, 2007 | Pubmed ID: 17202497
Tea epigallocatechin-3-gallate increases 8-isoprostane level and induces caudal regression in developing rat embryos.
Free radical biology & medicine Aug, 2007 | Pubmed ID: 17640562
Safety evaluation of commonly used Chinese herbal medicines during pregnancy in mice.
Human reproduction (Oxford, England) Aug, 2012 | Pubmed ID: 22647451
Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice.
Angiogenesis Jan, 2013 | Pubmed ID: 22948799
A review of pinealectomy-induced melatonin-deficient animal models for the study of etiopathogenesis of adolescent idiopathic scoliosis.
International journal of molecular sciences Sep, 2014 | Pubmed ID: 25238413
Correction: wai, m.g.C., et Al. A review of pinealectomy-induced melatonin-deficient animal models for the study of etiopathogenesis of adolescent idiopathic scoliosis. Int. J. Mol. Sci. 2014, 15, 16484-16499.
International journal of molecular sciences Jan, 2015 | Pubmed ID: 25642756
A prodrug of green tea polyphenol (-)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer.
Cancer letters 01, 2018 | Pubmed ID: 29024813
Long non-coding RNA HAND2-AS1 inhibits invasion and metastasis in endometrioid endometrial carcinoma through inactivating neuromedin U.
Cancer letters 01, 2018 | Pubmed ID: 29107108
Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis.
Archives of gynecology and obstetrics 03, 2018 | Pubmed ID: 29327157
Efficacy, safety and recurrence of new progestins and selective progesterone receptor modulator for the treatment of endometriosis: a comparison study in mice.
Reproductive biology and endocrinology : RB&E Apr, 2018 | Pubmed ID: 29615065
Morphology-Based Whole Embryo Culture for Developmental Toxicity of Drugs.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29896692
Decreased MUC1 in endometrium is an independent receptivity marker in recurrent implantation failure during implantation window.
Reproductive biology and endocrinology : RB&E Jun, 2018 | Pubmed ID: 29929546
The link between immunity, autoimmunity and endometriosis: a literature update.
Autoimmunity reviews Oct, 2018 | Pubmed ID: 30107265
Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment.
Medicina (Kaunas, Lithuania) Mar, 2019 | Pubmed ID: 30934763
Evaluation of in vitro embryotoxicity tests for Chinese herbal medicines.
Reproductive toxicology (Elmsford, N.Y.) 10, 2019 | Pubmed ID: 31228572
Localization of Mucin 1 in endometrial luminal epithelium and its expression in women with reproductive failure during implantation window.
Journal of molecular histology Dec, 2019 | Pubmed ID: 31555952
Effects of high progesterone in in-vitro fertilization cycle on DNA methylation and gene expression of adhesion molecules on endometrium during implantation window.
Journal of assisted reproduction and genetics Jan, 2020 | Pubmed ID: 31758513
Whole genome miRNA profiling revealed miR-199a as potential placental pathogenesis of selective fetal growth restriction in monochorionic twin pregnancies.
Placenta 03, 2020 | Pubmed ID: 32063549
Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer.
BMC cancer Oct, 2020 | Pubmed ID: 33023525
Autophagy signals orchestrate chemoresistance of gynecological cancers.
Biochimica et biophysica acta. Reviews on cancer 04, 2021 | Pubmed ID: 33600824
Diclofenac-induced embryotoxicity is associated with increased embryonic 8-isoprostaglandin F2alpha level in rat whole embryo culture.
Reproductive toxicology (Elmsford, N.Y.) , 2002 | Pubmed ID: 12401513
Quantifying F2-isoprostanes in umbilical cord blood of newborn by gas chromatography-mass spectrometry.
Analytical biochemistry May, 2003 | Pubmed ID: 12694733
The effect of intra-abdominal pressure on the generation of 8-iso prostaglandin F2alpha during laparoscopy in rabbits.
Human reproduction (Oxford, England) Oct, 2003 | Pubmed ID: 14507842
Molecular hierarchy in neurons differentiated from mouse ES cells containing a single human chromosome 21.
Biochemical and biophysical research communications Feb, 2004 | Pubmed ID: 14733910
Trolox-equivalent antioxidant capacity assay versus oxygen radical absorbance capacity assay in plasma.
Clinical chemistry May, 2004 | Pubmed ID: 15105359
In vitro exposure to carbon dioxide induces oxidative stress in human peritoneal mesothelial cells.
Human reproduction (Oxford, England) Jun, 2004 | Pubmed ID: 15105394
Determination of catechins and catechin gallates in tissues by liquid chromatography with coulometric array detection and selective solid phase extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Oct, 2004 | Pubmed ID: 15380714
Meconium-stained liquor during labor is associated with raised neonatal cord blood 8-iso-prostaglandin F2alpha concentration.
American journal of obstetrics and gynecology Jan, 2005 | Pubmed ID: 15672038
Relationship between isoprostane concentrations, metabolic acidosis, and morbid neonatal outcome.
Clinical chemistry Jul, 2005 | Pubmed ID: 15976110
Partial neuroprotective effect of pretreatment with tanshinone IIA on neonatal hypoxia-ischemia brain damage.
Pediatric research Oct, 2005 | Pubmed ID: 16189210
Metabolomic and bioinformatic analyses in asphyxiated neonates.
Clinical biochemistry Mar, 2006 | Pubmed ID: 16460720
Determination of ofloxacin and moxifloxacin and their penetration in human aqueous and vitreous humor by using high-performance liquid chromatography fluorescence detection.
Analytical biochemistry Jun, 2006 | Pubmed ID: 16620758
Pharmacokinetic studies of green tea catechins in maternal plasma and fetuses in rats.
Journal of pharmaceutical sciences Jun, 2006 | Pubmed ID: 16625654
Pro-oxidative effects of tea and polyphenols, epigallocatechin-3-gallate and epigallocatechin, on G6PD-deficient erythrocytes in vitro.
International journal of molecular medicine Nov, 2006 | Pubmed ID: 17016632
Measuring triamcinolone acetonide in aqueous humor by gas chromatography-electron-capture negative-ion mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Mar, 2007 | Pubmed ID: 17097356
Differential aqueous and vitreous concentrations of moxifloxacin and ofloxacin after topical administration one hour before vitrectomy.
American journal of ophthalmology Aug, 2007 | Pubmed ID: 17659971
Method to determine stability and recovery of carboprost and misoprostol in infusion preparations.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Sep, 2007 | Pubmed ID: 17692579
Mutations of t-complex testis expressed gene 5 transcripts in the testis of sterile t-haplotype mutant mouse.
Asian journal of andrology Mar, 2008 | Pubmed ID: 18286210
Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development.
Genes & development Jul, 2008 | Pubmed ID: 18593884
Human normal tear proteome.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Jun, 2009 | Pubmed ID: 18953555
Green tea catechins and their oxidative protection in the rat eye.
Journal of agricultural and food chemistry Feb, 2010 | Pubmed ID: 20085274
Fetal stromal niches enhance human embryonic stem cell-derived hematopoietic differentiation and globin switch.
Stem cells and development Jan, 2011 | Pubmed ID: 20715903
Stem cell-like properties of human umbilical cord lining epithelial cells and the potential for epidermal reconstitution.
Cytotherapy Feb, 2011 | Pubmed ID: 20735166
Classification of pathogenic or benign status of CNVs detected by microarray analysis.
Expert review of molecular diagnostics Sep, 2010 | Pubmed ID: 20843196
Thrombopoietin protects against doxorubicin-induced cardiomyopathy, improves cardiac function, and reversely alters specific signalling networks.
European journal of heart failure Apr, 2011 | Pubmed ID: 21330293
Gestational and lactational transfer of melamine following gavage administration of a single dose to rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Jul, 2011 | Pubmed ID: 21457748
Association of hemopexin in tear film and conjunctival macrophages with vernal keratoconjunctivitis.
Archives of ophthalmology (Chicago, Ill. : 1960) Apr, 2011 | Pubmed ID: 21482871
Gene dosage imbalance of human chromosome 21 in mouse embryonic stem cells differentiating to neurons.
Gene Aug, 2011 | Pubmed ID: 21549184
Monoamine oxidase a expression is vital for embryonic brain development by modulating developmental apoptosis.
The Journal of biological chemistry Aug, 2011 | Pubmed ID: 21697081
Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo.
Fertility and sterility Oct, 2011 | Pubmed ID: 21821246
The Roles of Glutathione Peroxidases during Embryo Development.
Frontiers in molecular neuroscience , 2011 | Pubmed ID: 21847368
Chinese herbal medicines for threatened miscarriage.
The Cochrane database of systematic reviews May, 2012 | Pubmed ID: 22592730
Adverse outcomes of Chinese medicines used for threatened miscarriage: a systematic review and meta-analysis.
Human reproduction update , 2012 | Pubmed ID: 22661551
Thrombopoietin improved ventricular function and regulated remodeling genes in a rat model of myocardial infarction.
International journal of cardiology Jul, 2012 | Pubmed ID: 22770769
Monoamine oxidases in development.
Cellular and molecular life sciences : CMLS Feb, 2013 | Pubmed ID: 22782111
A paradoxical teratogenic mechanism for retinoic acid.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2012 | Pubmed ID: 22869719
A randomized, double-blind, multiple-dose escalation study of a Chinese herbal medicine preparation (Dang Gui Buxue Tang) for moderate to severe menopausal symptoms and quality of life in postmenopausal women.
Menopause (New York, N.Y.) Sep, 2012 | Pubmed ID: 22990757
MicroRNA-182 plays an onco-miRNA role in cervical cancer.
Gynecologic oncology Apr, 2013 | Pubmed ID: 23313739
Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis.
Angiogenesis Jan, 2013 | Pubmed ID: 23334337
Suppression of malignancy by Smad3 in mouse embryonic stem cell formed teratoma.
Stem cell reviews and reports Oct, 2013 | Pubmed ID: 23794057
Functional role of Mst1/Mst2 in embryonic stem cell differentiation.
PloS one , 2013 | Pubmed ID: 24224013
Pregnancy outcomes, embryonic and fetal development in maternal exposure to Chinese medicines.
Birth defects research. Part C, Embryo today : reviews Dec, 2013 | Pubmed ID: 24339038
Human fetal liver stromal cell co-culture enhances the differentiation of pancreatic progenitor cells into islet-like cell clusters.
Stem cell reviews and reports Apr, 2014 | Pubmed ID: 24395006
Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies.
Gene Apr, 2014 | Pubmed ID: 24406620
Serotonin receptor 6 mediates defective brain development in monoamine oxidase A-deficient mouse embryos.
The Journal of biological chemistry Mar, 2014 | Pubmed ID: 24497636
Systematic Review of Chinese Medicine for Miscarriage during Early Pregnancy.
Evidence-based complementary and alternative medicine : eCAM , 2014 | Pubmed ID: 24648851
Pro-oxidative and antioxidative controls and signaling modification of polyphenolic phytochemicals: contribution to health promotion and disease prevention?
Journal of agricultural and food chemistry May, 2014 | Pubmed ID: 24779775
Performance of chromosomal microarray for patients with intellectual disabilities/developmental delay, autism, and multiple congenital anomalies in a Chinese cohort.
Molecular cytogenetics , 2014 | Pubmed ID: 24926319
Cryptotanshinone reverses ovarian insulin resistance in mice through activation of insulin signaling and the regulation of glucose transporters and hormone synthesizing enzymes.
Fertility and sterility Aug, 2014 | Pubmed ID: 24973798
Determination of exogenous epigallocatechin gallate peracetate in mouse plasma using liquid chromatography with quadrupole time-of-flight mass spectrometry.
Journal of separation science Dec, 2014 | Pubmed ID: 25250898
Safety of Chinese herbal medicines during pregnancy.
Journal of applied toxicology : JAT May, 2015 | Pubmed ID: 25663446
Differential expression of vascular endothelial growth factor angiogenic factors in different endometrial compartments in women who have an elevated progesterone level before oocyte retrieval, during in vitro fertilization-embryo transfer treatment.
Fertility and sterility Oct, 2015 | Pubmed ID: 26143364
Effects of EGCG content in green tea extract on pharmacokinetics, oxidative status and expression of inflammatory and apoptotic genes in the rat ocular tissues.
The Journal of nutritional biochemistry Nov, 2015 | Pubmed ID: 26362107
Adverse reproductive effects of maternal low-dose melamine exposure during pregnancy in rats.
Environmental toxicology Jan, 2017 | Pubmed ID: 26589250
Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1.
Nature communications Dec, 2015 | Pubmed ID: 26658965
Chinese herbal medicines for unexplained recurrent miscarriage.
The Cochrane database of systematic reviews Jan, 2016 | Pubmed ID: 26760986
Hypoxia inducible factor and microvessels in peri-implantation endometrium of women with recurrent miscarriage.
Fertility and sterility Jun, 2016 | Pubmed ID: 27018158
Local administration of siRNA through Microneedle: Optimization, Bio-distribution, Tumor Suppression and Toxicity.
Scientific reports 07, 2016 | Pubmed ID: 27457182
Genetic variants associated with gestational diabetes mellitus: a meta-analysis and subgroup analysis.
Scientific reports Jul, 2016 | Pubmed ID: 27468700
Secretome of Human Fetal Mesenchymal Stem Cell Ameliorates Replicative Senescen.
Stem cells and development Nov, 2016 | Pubmed ID: 27539404
Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes.
Diabetes Apr, 2017 | Pubmed ID: 28087565
The flame retardant 2,2',4,4'-Tetrabromodiphenyl ether enhances the expression of corticotropin-releasing hormone in the placental cell model JEG-3.
Chemosphere May, 2017 | Pubmed ID: 28189027
Correlation between three-dimensional power Doppler and morphometric measurement of endometrial vascularity at the time of embryo implantation in women with unexplained recurrent miscarriage.
Journal of molecular histology Jun, 2017 | Pubmed ID: 28451773
Physiological and pathological angiogenesis in endometrium at the time of embryo implantation.
American journal of reproductive immunology (New York, N.Y. : 1989) Aug, 2017 | Pubmed ID: 28466568
Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin.
Nature communications May, 2017 | Pubmed ID: 28516904
The regulations and role of circadian clock and melatonin in uterine receptivity and pregnancy-An immunological perspective.
American journal of reproductive immunology (New York, N.Y. : 1989) Aug, 2017 | Pubmed ID: 28585704
Effect of Acupuncture and Clomiphene in Chinese Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial.
JAMA 06, 2017 | Pubmed ID: 28655015
Effects of high progesterone level on the day of human chorionic gonadotrophin administration in in vitro fertilization cycles on epigenetic modification of endometrium in the peri-implantation period.
Fertility and sterility Aug, 2017 | Pubmed ID: 28778281
Transcriptomic profiles in peripheral blood between women with unexplained recurrent implantation failure and recurrent miscarriage and the correlation with endometrium: A pilot study.
PloS one , 2017 | Pubmed ID: 29216287
Inhibition of coiled coil domain containing protein 69 enhances platinum-induced apoptosis in ovarian cancer cells.
Oncotarget Nov, 2017 | Pubmed ID: 29254192
Effects of low-dose melamine exposure during pregnancy on maternal and fetal kidneys in rats.
Environmental toxicology Mar, 2018 | Pubmed ID: 29265596
Increased expression of angiogenic cytokines in CD56+ uterine natural killer cells from women with recurrent miscarriage.
Cytokine 10, 2018 | Pubmed ID: 29396049
MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target.
European journal of immunology Jun, 2018 | Pubmed ID: 29460338
Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction.
Human reproduction (Oxford, England) 04, 2018 | Pubmed ID: 29471520
The Therapeutic Effects of a Traditional Chinese Medicine Formula Wuzi Yanzong Pill for the Treatment of Oligoasthenozoospermia: A Meta-Analysis of Randomized Controlled Trials.
Evidence-based complementary and alternative medicine : eCAM , 2018 | Pubmed ID: 29576794
Comparison of the prevalence of chronic endometritis as determined by means of different diagnostic methods in women with and without reproductive failure.
Fertility and sterility 05, 2018 | Pubmed ID: 29778382
Corrigendum to "The Therapeutic Effects of a Traditional Chinese Medicine Formula Wuzi Yanzong Pill for the Treatment of Oligoasthenozoospermia: A Meta-Analysis of Randomized Controlled Trials".
Evidence-based complementary and alternative medicine : eCAM , 2018 | Pubmed ID: 30034499
Metabolomics of Green-Tea Catechins on Vascular-Endothelial-Growth-Factor-Stimulated Human-Endothelial-Cell Survival.
Journal of agricultural and food chemistry Dec, 2018 | Pubmed ID: 30406651
Intrauterine infusion of human chorionic gonadotropin before embryo transfer in IVF/ET cycle: The critical review.
American journal of reproductive immunology (New York, N.Y. : 1989) Feb, 2019 | Pubmed ID: 30589989
Homology-independent multiallelic disruption via CRISPR/Cas9-based knock-in yields distinct functional outcomes in human cells.
BMC biology Dec, 2018 | Pubmed ID: 30593266
Overexpression of CCDC69 activates p14/MDM2/p53 pathway and confers cisplatin sensitivity.
Journal of ovarian research Jan, 2019 | Pubmed ID: 30651135
Genetic variants in promoter regions associated with type 2 diabetes mellitus: A large-scale meta-analysis and subgroup analysis.
Journal of cellular biochemistry Aug, 2019 | Pubmed ID: 30860284
Effects of hyperhomocysteinaemia and metabolic syndrome on reproduction in women with polycystic ovary syndrome: a secondary analysis.
Reproductive biomedicine online Jun, 2019 | Pubmed ID: 30979610
YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells.
The EMBO journal May, 2019 | Pubmed ID: 30979776
The high-risk HPV oncogene E7 upregulates miR-182 expression through the TGF-β/Smad pathway in cervical cancer.
Cancer letters Sep, 2019 | Pubmed ID: 31247272
Endocrine characteristics, body mass index and metabolic syndrome in women with polycystic ovary syndrome.
Reproductive biomedicine online Nov, 2019 | Pubmed ID: 31444050
Efficacy and Safety of Chinese Herbal Medicine on Ovarian Cancer After Reduction Surgery and Adjuvant Chemotherapy: A Systematic Review and Meta-Analysis.
Frontiers in oncology , 2019 | Pubmed ID: 31475101
EDNRB isoform 3 confers Temozolomide resistance in A375 melanoma cells by modulating membrane potential, reactive oxygen species and mitochondrial Ca.
Cancer management and research , 2019 | Pubmed ID: 31496797
Endometrium imaging using real-time rotational optical coherence tomography imaging system: A pilot, prospective and ex-vivo study.
Medicine Nov, 2019 | Pubmed ID: 31689821
The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials.
Evidence-based complementary and alternative medicine : eCAM , 2019 | Pubmed ID: 31915452
Association between chronic endometritis and uterine natural killer cell density in women with recurrent miscarriage: clinical implications.
The journal of obstetrics and gynaecology research Jun, 2020 | Pubmed ID: 32189458
Placental microRNA dataset of monochorionic twin pregnancies with and without selective fetal growth restriction.
Data in brief Jun, 2020 | Pubmed ID: 32274407
Monochorionic twins with selective fetal growth restriction: insight from placental whole-transcriptome analysis.
American journal of obstetrics and gynecology Nov, 2020 | Pubmed ID: 32437666
MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells.
Molecular therapy. Nucleic acids Sep, 2020 | Pubmed ID: 32599451
Characteristics of Circular RNA Expression Profiles of Porcine Granulosa Cells in Healthy and Atretic Antral Follicles.
International journal of molecular sciences Jul, 2020 | Pubmed ID: 32717899
An Innovative Artificial Intelligence-Based App for the Diagnosis of Gestational Diabetes Mellitus (GDM-AI): Development Study.
Journal of medical Internet research Sep, 2020 | Pubmed ID: 32930674
Uterine CD56 cell density and euploid miscarriage in women with a history of recurrent miscarriage: A clinical descriptive study.
European journal of immunology 02, 2021 | Pubmed ID: 32976648
Single-Cell RNA-Seq Reveals that CD9 Is a Negative Marker of Glucose-Responsive Pancreatic β-like Cells Derived from Human Pluripotent Stem Cells.
Stem cell reports Nov, 2020 | Pubmed ID: 33096048
Successful implantation is associated with a transient increase in serum pro-inflammatory cytokine profile followed by a switch to anti-inflammatory cytokine profile prior to confirmation of pregnancy.
Fertility and sterility 04, 2021 | Pubmed ID: 33272613
Transcriptome Analysis of Porcine Granulosa Cells in Healthy and Atretic Follicles: Role of Steroidogenesis and Oxidative Stress.
Antioxidants (Basel, Switzerland) Dec, 2020 | Pubmed ID: 33379347
Novel Genetic Variants of Promoter in Gestational Diabetes Mellitus and its Molecular Regulation in Adipogenesis.
Frontiers in endocrinology , 2020 | Pubmed ID: 33551986
Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study.
EBioMedicine Mar, 2021 | Pubmed ID: 33684886
Characterization of Long Non-Coding RNA Profiles in Porcine Granulosa Cells of Healthy and Atretic Antral Follicles: Implications for a Potential Role in Apoptosis.
International journal of molecular sciences Mar, 2021 | Pubmed ID: 33800928
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review.
Medicinal research reviews Jul, 2021 | Pubmed ID: 33948974
Effective Aspirin Treatment of Women at Risk for Preeclampsia Delays the Metabolic Clock of Gestation.
Hypertension (Dallas, Tex. : 1979) Nov, 2021 | Pubmed ID: 34225470
Evidence on Efficacy and Safety of Chinese Medicines Combined Western Medicines Treatment for Breast Cancer With Endocrine Therapy.
Frontiers in oncology , 2021 | Pubmed ID: 34235077
Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.
Frontiers in immunology , 2021 | Pubmed ID: 34367125
R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling.
Blood advances Nov, 2021 | Pubmed ID: 34500454
Molecular Mechanism and Pathways of Normal Human Parturition in Different Gestational Tissues: A Systematic Review of Transcriptome Studies.
Frontiers in physiology , 2021 | Pubmed ID: 34566691
Therapeutic effects of green tea on endometriosis.
Critical reviews in food science and nutrition , 2023 | Pubmed ID: 34620005
The identification of endometrial immune cell densities and clustering analysis in the mid-luteal phase as predictor for pregnancy outcomes after IVF-ET treatment.
Journal of reproductive immunology Nov, 2021 | Pubmed ID: 34627075
An , and Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis.
Frontiers in pharmacology , 2021 | Pubmed ID: 34721014
Associations of maternal weight status with the risk of offspring atopic dermatitis and wheezing by 1 year of age.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Jan, 2022 | Pubmed ID: 34806795
Maternal and Neonatal 3-epi-25-hydroxyvitamin D Concentration and Factors Influencing Their Concentrations.
Journal of the Endocrine Society Jan, 2022 | Pubmed ID: 34909515
A new Hypoxic Ischemic Encephalopathy model in neonatal rats.
Heliyon Dec, 2021 | Pubmed ID: 35024484
Single Cell Proteomics Profiling Reveals That Embryo-Secreted TNF-α Plays a Critical Role During Embryo Implantation to the Endometrium.
Reproductive sciences (Thousand Oaks, Calif.) May, 2022 | Pubmed ID: 35084714
YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells.
Diabetes May, 2022 | Pubmed ID: 35113157
Gestational weight gain rates in the first and second trimesters are associated with small for gestational age among underweight women: a prospective birth cohort study.
BMC pregnancy and childbirth Feb, 2022 | Pubmed ID: 35123424
Serial changes in two immune checkpoint receptors and ligands, Tim-3/Gal-9 and PD-1/PD-L1 in peripheral blood prior to miscarriage: Comparison with pregnancies resulting in a live birth.
American journal of reproductive immunology (New York, N.Y. : 1989) May, 2022 | Pubmed ID: 35130363
The Key Role of Peroxisomes in Follicular Growth, Oocyte Maturation, Ovulation, and Steroid Biosynthesis.
Oxidative medicine and cellular longevity , 2022 | Pubmed ID: 35154572
Risk factors associated with breakdown of perineal laceration repair after vaginal birth.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Jul, 2022 | Pubmed ID: 35166164
Correction: Single Cell Proteomics Profiling Reveals That Embryo-Secreted TNF-α Plays a Critical Role During Embryo Implantation to the Endometrium.
Reproductive sciences (Thousand Oaks, Calif.) May, 2022 | Pubmed ID: 35174472
A human pluripotent stem cell-based model of SARS-CoV-2 infection reveals an ACE2-independent inflammatory activation of vascular endothelial cells through TLR4.
Stem cell reports Mar, 2022 | Pubmed ID: 35180397
Aspirin Repurposing in Folate-Decorated Nanoparticles: Another Way to Target Breast Cancer.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 35187067
Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors.
Nature communications Feb, 2022 | Pubmed ID: 35210419
Metabolomic markers of biological fluid in women with reproductive failure: a systematic review of current literatures.
Biology of reproduction Jun, 2022 | Pubmed ID: 35226730
Expression of vascular endothelial growth factor A (VEGFA), placental growth factor (PlGF) and insulin-like growth factor 1 (IGF-1) in serum from women undergoing frozen embryo transfer.
Human fertility (Cambridge, England) Dec, 2023 | Pubmed ID: 35243939
Umbilical Cord Blood Mononuclear Cell Treatment for Neonatal Rats With Hypoxic Ischemia.
Frontiers in cellular neuroscience , 2022 | Pubmed ID: 35308119
Systematic review update and meta-analysis of randomized and non-randomized controlled trials of ovarian stimulation versus artificial cycle for endometrial preparation prior to frozen embryo transfer in women with polycystic ovary syndrome.
Reproductive biology and endocrinology : RB&E Apr, 2022 | Pubmed ID: 35366912
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Frontiers in endocrinology , 2022 | Pubmed ID: 35370991
Efficacy and Safety of Chinese Herbal Medicine for Endometriosis Associated Pain.
The American journal of Chinese medicine , 2022 | Pubmed ID: 35475975
Vitamin D Levels During Pregnancy Are Associated With Offspring Telomere Length: A Longitudinal Mother-Child Study.
The Journal of clinical endocrinology and metabolism Aug, 2022 | Pubmed ID: 35588001
Dynamic changes in maternal immune biomarkers during labor in nulliparous vs multiparous women.
American journal of obstetrics and gynecology Oct, 2022 | Pubmed ID: 35609644
Developmental Neuropathology and Neurodegeneration of Down Syndrome: Current Knowledge in Humans.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35676933
Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro.
Cell biology and toxicology Feb, 2023 | Pubmed ID: 35701726
The efficacy and safety of combined chinese herbal medicine and western medicine therapy for COVID-19: a systematic review and meta-analysis.
Chinese medicine Jun, 2022 | Pubmed ID: 35729581
Green Tea Epigallocatechin-3-Gallate Regulates Autophagy in Male and Female Reproductive Cancer.
Frontiers in pharmacology , 2022 | Pubmed ID: 35860020
Prenatal and Postnatal Therapies for Down's Syndrome and Associated Developmental Anomalies and Degenerative Deficits: A Systematic Review of Guidelines and Trials.
Frontiers in medicine , 2022 | Pubmed ID: 35865169
What We Have Learned from Animal Models to Understand the Etiology and Pathology of Endometrioma-Related Infertility.
Biomedicines Jun, 2022 | Pubmed ID: 35884788
Systemic and Ocular Anti-Inflammatory Mechanisms of Green Tea Extract on Endotoxin-Induced Ocular Inflammation.
Frontiers in endocrinology , 2022 | Pubmed ID: 35909558
Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine.
Blood cancer discovery Nov, 2022 | Pubmed ID: 35960210
Is polycystic ovary syndrome undervalued in China?
The Lancet regional health. Western Pacific Aug, 2022 | Pubmed ID: 36091882
Melatonin in Endometriosis: Mechanistic Understanding and Clinical Insight.
Nutrients Oct, 2022 | Pubmed ID: 36235740
A prospective study comparing the inflammation-related cytokine and chemokine profile from the day of blastocyst transfer to 7 weeks of gestation between pregnancies that did or did not result in a miscarriage.
Journal of reproductive immunology Dec, 2022 | Pubmed ID: 36272272
Untargeted metabolomic analysis of aqueous humor in diabetic macular edema.
Molecular vision , 2022 | Pubmed ID: 36284671
Determination of (-)-epigallocatechin-3-gallate octaacetate and its metabolites in plasma of rats for pharmacokinetic study by ultra-performance-liquid-chromatography coupled to quadrupole-time-of-flight-mass-spectrometry.
Frontiers in pharmacology , 2022 | Pubmed ID: 36304154
Re-evaluation of mouse models of endometriosis for pathological and immunological research.
Frontiers in immunology , 2022 | Pubmed ID: 36466829
Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children's glucose metabolism-a longitudinal study.
BMC medicine Dec, 2022 | Pubmed ID: 36536359
In vitro tests to evaluate embryotoxicity and irritation of Chinese herbal medicine (Pentaherbs formulation) for atopic dermatitis.
Journal of ethnopharmacology Apr, 2023 | Pubmed ID: 36632857
Impacts of endometrioma on ovarian aging from basic science to clinical management.
Frontiers in endocrinology , 2022 | Pubmed ID: 36686440
Efficacy of acupuncture for endometriosis-associated pain: a multicenter randomized single-blind placebo-controlled trial.
Fertility and sterility May, 2023 | Pubmed ID: 36716811
Chinese herbal medicine for threatened miscarriage: An updated systematic review and meta-analysis.
Frontiers in pharmacology , 2023 | Pubmed ID: 36865912
Myeloid-derived suppressor cells: A new emerging player in endometriosis.
International review of cell and molecular biology , 2023 | Pubmed ID: 36967153
The impact of endometrial scratch performed in mid-luteal phase on the endometrium whole genome transcriptomic profiles in following menstrual cycle.
Human fertility (Cambridge, England) Oct, 2023 | Pubmed ID: 37029627
Platelet count in preeclampsia: a systematic review and meta-analysis.
American journal of obstetrics & gynecology MFM Jul, 2023 | Pubmed ID: 37098392
Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis.
The American journal of Chinese medicine , 2023 | Pubmed ID: 37120704
Acupuncture and Doxylamine-Pyridoxine for Nausea and Vomiting in Pregnancy : A Randomized, Controlled, 2 2 Factorial Trial.
Annals of internal medicine Jul, 2023 | Pubmed ID: 37335994
Anti-HPV16 oncoproteins siRNA therapy for cervical cancer using a novel transdermal peptide PKU12.
Frontiers in oncology , 2023 | Pubmed ID: 37350944
Single-cell analysis reveals transcriptomic and epigenomic impacts on the maternal-fetal interface following SARS-CoV-2 infection.
Nature cell biology Jul, 2023 | Pubmed ID: 37400500
Green Tea Catechins as Therapeutic Antioxidants for Glaucoma Treatment.
Antioxidants (Basel, Switzerland) Jun, 2023 | Pubmed ID: 37507860
Pathophysiological Insight into Fatty Acid-Binding Protein-4: Multifaced Roles in Reproduction, Pregnancy, and Offspring Health.
International journal of molecular sciences Aug, 2023 | Pubmed ID: 37628833
Effects of maternal probiotic supplementation on breast milk microbiome and infant gut microbiome and health: a systematic review and meta-analysis of randomized controlled trials.
American journal of obstetrics & gynecology MFM Nov, 2023 | Pubmed ID: 37660760
Decreased serum soluble programmed cell death ligand-1 level as a potential biomarker for missed miscarriage.
Human reproduction (Oxford, England) Nov, 2023 | Pubmed ID: 37671597
Association of angiotensin II and receptors in peri-implantation endometrium with microvessel density and pregnancy outcomes of women with recurrent implantation failure after embryo transfer.
Frontiers in endocrinology , 2023 | Pubmed ID: 37711897
Acupuncture improves the emotion domain and lipid profiles in women with polycystic ovarian syndrome: a secondary analysis of a randomized clinical trial.
Frontiers in endocrinology , 2023 | Pubmed ID: 37711905
Comprehensive molecular expression profiling of SARS-CoV-associated factors in the endometrium across the menstrual cycle and elevated susceptibility in women with recurrent pregnancy loss.
Frontiers in genetics , 2023 | Pubmed ID: 37854057
Is elevated baseline SHBG associated with increased ovulation?
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Dec, 2023 | Pubmed ID: 37913814
Chinese herbal medicines as complementary therapy to in vitro fertilization-embryo transfer in women with infertility: protocols and applications.
Human fertility (Cambridge, England) Oct, 2023 | Pubmed ID: 37937818
Diminished Ovarian Reserve in Endometriosis: Insights from In Vitro, In Vivo, and Human Studies-A Systematic Review.
International journal of molecular sciences Nov, 2023 | Pubmed ID: 37958954
The Association of Prenatal Vitamin D Status With Pregnancy and Neonatal Outcomes.
Journal of the Endocrine Society Dec, 2023 | Pubmed ID: 38075561
Antiviral Effects and Mechanisms of Green Tea Catechins on Influenza: A Perception on Combating Symptoms from COVID-19.
Current topics in medicinal chemistry , 2024 | Pubmed ID: 38291871
Interplay of Ferroptosis and Cuproptosis in Cancer: Dissecting Metal-Driven Mechanisms for Therapeutic Potentials.
Cancers Jan, 2024 | Pubmed ID: 38339263
Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis.
Journal of pharmaceutical analysis Jan, 2024 | Pubmed ID: 38352946
Acupuncture and Doxylamine-Pyridoxine for Nausea and Vomiting in Pregnancy.
Annals of internal medicine Feb, 2024 | Pubmed ID: 38373319
Amelioration of Functional, Metabolic, and Morphological Deterioration in the Retina following Retinal Detachment by Green Tea Extract.
Antioxidants (Basel, Switzerland) Feb, 2024 | Pubmed ID: 38397833
Isolation of myeloid-derived suppressor cells (MDSC) from endometriotic mice model and their immunomodulatory functions.
Methods in cell biology , 2024 | Pubmed ID: 38555157
Thrombospondin-1 Regulates Trophoblast Necroptosis via NEDD4-Mediated Ubiquitination of TAK1 in Preeclampsia.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Apr, 2024 | Pubmed ID: 38569496
Cycasin derivative: a potential embryotoxic component of rhizome for limb malformation.
Toxicology research Apr, 2024 | Pubmed ID: 38623091
The Nrf2/ARE pathway as a potential target to ameliorate atrazine-induced endocrine disruption in granulosa cells.
Poultry science Jun, 2024 | Pubmed ID: 38631229
Aspirin versus metformin in pregnancies at high risk of preterm pre-eclampsia in China (AVERT): protocol for a multicentre, double-blind, 3-arm randomised controlled trial.
BMJ open Apr, 2024 | Pubmed ID: 38631826
Lycopene Protects against Atrazine-Induced Kidney STING-Dependent PANoptosis through Stabilizing mtDNA via Interaction with Sam50/PHB1.
Journal of agricultural and food chemistry Jul, 2024 | Pubmed ID: 38820047
Preventive effect of prenatal maternal oral probiotic supplementation on neonatal jaundice (POPS Study): A protocol for the randomised double-blind placebo-controlled clinical trial.
BMJ open Jun, 2024 | Pubmed ID: 38851232
Unique anti-angiogenic effects, pharmacological targets and therapeutic mechanisms of Chinese herbal medicines for endometriosis.
Genes & diseases Sep, 2024 | Pubmed ID: 38882012
Proteomics approach to discovering non-invasive diagnostic biomarkers and understanding the pathogenesis of endometriosis: a systematic review and meta-analysis.
Journal of translational medicine Jul, 2024 | Pubmed ID: 39061077
Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation.
American journal of reproductive immunology (New York, N.Y. : 1989) Aug, 2024 | Pubmed ID: 39158962
Microbiota-targeted interventions and clinical implications for maternal-offspring health: An umbrella review of systematic reviews and meta-analyses of randomised controlled trials.
Journal of global health Sep, 2024 | Pubmed ID: 39269153
Identification and Potential Clinical Utility of Common Genetic Variants in Gestational Diabetes among Chinese Pregnant Women.
Diabetes & metabolism journal Sep, 2024 | Pubmed ID: 39301664
Yiwei Zhao1,
Gene Chi Wai Man1,2,
Loucia Kit Ying Chan1,
Xi Guo1,
Yingyu Liu3,
Tao Zhang1,
Joseph Kwong1,4,
Chi Chiu Wang1,5,
Xiaoyan Chen3,
Tin Chiu Li1
1Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital,
2Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Prince of Wales Hospital,
3Department of Obstetrics and Gynaecology, Shenzhen Baoan Women’s and Children’s Hospital, Shenzhen University,
4School of Medicine, Faculty of Medicine and Health Sciences, Keele University,
5Li Ka Shing Institute of Health Sciences; School of Biomedical Sciences, The Chinese University of Hong Kong
1Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong,
2Reproduction and Development, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong,
3School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong,
4Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine, The Chinese University of Hong Kong
Lu Chen1,
Loucia Kit Ying Chan1,
Stacey Chui Yiu Wong1,
Joshua Jing Xi Li2,
Jacqueline Pui Wah Chung1,
Chi Chiu Wang1,3,4,5,
Mingqing Li6,7,8,
Tao Zhang1
1Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong,
2Department of Pathology, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital,
3Reproduction and Development Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong,
4School of Biomedical Sciences, Prince of Wales Hospital, The Chinese University of Hong Kong,
5Chinese University of Hong Kong - Sichuan University Joint Laboratory in Reproductive Medicine, The Chinese University of Hong Kong,
6Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University,
7NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Fudan University,
8Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Hospital of Obstetrics and Gynecology, Fudan University
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